Details for gene: TMEM127


This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2010]


Symbol
TMEM127
Name
transmembrane protein 127
Entrez ID
55654
Ensembl ID
ENSG00000135956    (more details)
KEGG ID
hsa:55654    (more details)
OMIM ID
613403
Uniprot ID
O75204  
GO ID
hsa:55654    (more details)
Chromosome
2
Strand
-1
Start
96248514
End
96265997
miRNA Interactions
hsa-miR-15a-5p (RPM: 139.425) / hsa-miR-1277-5p (RPM: 3.0234) / hsa-miR-29b-3p (RPM: 118.8178) / hsa-miR-20a-5p (RPM: 55.9816) / hsa-miR-195-5p (RPM: 125.6474) / hsa-miR-29c-3p (RPM: 661.3514) / hsa-miR-15b-5p (RPM: 133.5752) / hsa-miR-29a-3p (RPM: 1246.9046) / hsa-miR-423-5p (RPM: 976.289) / hsa-miR-4739 (RPM: 0.01) / hsa-miR-124-3p (RPM: 4110.4386) / hsa-miR-34a-5p (RPM: 81.3502) / hsa-miR-16-5p (RPM: 2473.4704) / hsa-miR-106b-5p (RPM: 35.4204) / hsa-miR-424-5p (RPM: 9.04) / hsa-miR-27b-3p (RPM: 22876.2392) / hsa-miR-2276-3p (RPM: 0.6192) / hsa-miR-106a-5p (RPM: 7.9736) / hsa-miR-183-5p (RPM: 37556.6894) / hsa-miR-27a-3p (RPM: 980.3062) / hsa-miR-3613-3p (RPM: 0.8106) / hsa-miR-450b-5p (RPM: 4.6184) / hsa-miR-548c-3p (RPM: 0.0894) / hsa-miR-19b-3p (RPM: 197.0578) / hsa-miR-19a-3p (RPM: 25.4064) / hsa-miR-544a (RPM: 0.082) / hsa-miR-497-5p (RPM: 49.4968) / hsa-miR-3926 (RPM: 0.0072) / hsa-miR-5006-3p (RPM: 0.4468) / hsa-miR-5010-5p (RPM: 0.3386) / hsa-miR-18b-3p (RPM: 0.2006) / hsa-miR-4731-5p (RPM: 0.185) / hsa-miR-5699-3p (RPM: 0.4822) / hsa-miR-129-2-3p (RPM: 79.8688) / hsa-miR-520c-3p (RPM: 0.0046) / hsa-miR-582-3p (RPM: 12.5308) / hsa-miR-4510 (RPM: 7.6222) / hsa-miR-23b-5p (RPM: 1.333) / hsa-miR-589-5p (RPM: 54.2348) / hsa-miR-186-5p (RPM: 1645.2832) / hsa-miR-130b-3p (RPM: 68.2014) / hsa-miR-150-5p (RPM: 64.1654) / hsa-miR-429 (RPM: 100.5032) / hsa-miR-449b-3p (RPM: 0.0876) / hsa-miR-519d-3p (RPM: 0.0042) / hsa-miR-221-3p (RPM: 758.7978) / hsa-miR-449a (RPM: 1.3118) / hsa-miR-7-1-3p (RPM: 13.9534) / hsa-miR-3619-5p (RPM: 0.0804) / hsa-miR-520d-3p (RPM: 0.0042) / hsa-miR-372-3p (RPM: 0.0034) / hsa-miR-3190-5p (RPM: 0.0008) / hsa-miR-455-3p (RPM: 82.7264) / hsa-miR-7-5p (RPM: 19.3682) / hsa-miR-373-3p (RPM: 0.0958) / hsa-miR-548s (RPM: 0.1718) / hsa-miR-323a-3p (RPM: 23.6866) / hsa-miR-1226-5p (RPM: 0.426) / hsa-miR-214-3p (RPM: 21.2784) / hsa-miR-520a-3p (RPM: 0.0858) / hsa-miR-519b-3p (RPM: 0.0036) / hsa-miR-3126-5p (RPM: 0.6218) / hsa-miR-4753-5p (RPM: 0.097) / hsa-miR-4796-3p (RPM: 0.125) / hsa-miR-204-5p (RPM: 265062.0076) / hsa-miR-3158-5p (RPM: 0.0624) / hsa-miR-302d-3p (RPM: 0.0012) / hsa-miR-548ah-5p (RPM: 1.0636) / hsa-miR-519a-3p (RPM: 0.0036) / hsa-miR-4728-5p (RPM: 0.1204) / hsa-miR-3678-3p (RPM: 0.0274) / hsa-miR-142-5p (RPM: 245.4844) / hsa-miR-2467-3p (RPM: 0.0206) / hsa-miR-519c-3p (RPM: 0.0096) / hsa-miR-181d-5p (RPM: 168.2728) / hsa-miR-181b-5p (RPM: 3069.8278) / hsa-miR-4476 (RPM: 0.0016) / hsa-miR-138-2-3p (RPM: 0.1862) / hsa-miR-181c-5p (RPM: 1285.07) / hsa-miR-181a-5p (RPM: 52364.6344) / hsa-miR-4421 (RPM: 0.2216) / hsa-miR-302c-3p (RPM: 0.0012) / hsa-miR-185-5p (RPM: 29.191) / hsa-miR-139-5p (RPM: 36.887) / hsa-miR-449b-5p (RPM: 1.2108) / hsa-miR-21-3p (RPM: 238.3548) / hsa-miR-1-3p (RPM: 26.3428) / hsa-miR-486-3p (RPM: 65.2834) / hsa-miR-302b-3p (RPM: 0.006) / hsa-miR-34c-5p (RPM: 46.7356) / hsa-miR-30c-2-3p (RPM: 52.8714) / hsa-miR-149-3p (RPM: 0.3876) / hsa-miR-185-3p (RPM: 4.0636) / hsa-miR-5589-5p (RPM: 0.0034) / hsa-miR-1224-5p (RPM: 1.6668) / hsa-miR-642a-5p (RPM: 0.7748) / hsa-miR-769-3p (RPM: 3.6276) / hsa-miR-1238-3p (RPM: 0.0018) / hsa-miR-30c-1-3p (RPM: 36.5546) / hsa-miR-222-3p (RPM: 1699.0194) / hsa-miR-219a-1-3p (RPM: 2.3152) / hsa-miR-574-5p (RPM: 176.4618) / hsa-miR-512-3p (RPM: 0.4192) / hsa-miR-1976 (RPM: 0.0434) / hsa-miR-330-3p (RPM: 21.3424) / hsa-miR-874-3p (RPM: 170.3494) / hsa-miR-425-5p (RPM: 187.631) / hsa-miR-28-5p (RPM: 190.0872) / hsa-miR-93-5p (RPM: 357.1536) / hsa-miR-1914-3p (RPM: 0.0102) / hsa-miR-5094 (RPM: 0.1872) / hsa-miR-324-3p (RPM: 32.0094) / hsa-miR-93-3p (RPM: 9.5402) / hsa-miR-17-5p (RPM: 83.6404) / hsa-miR-20b-5p (RPM: 24.4036) / hsa-miR-609 (RPM: 0.0286) / hsa-miR-3125 (RPM: 1.2126) / hsa-miR-3916 (RPM: 0.1044) / hsa-miR-335-5p (RPM: 265.7294) / hsa-miR-1913 (RPM: 0.4166) / hsa-miR-877-5p (RPM: 44.6348) / hsa-miR-548ax (RPM: 0.008) / hsa-miR-4684-5p (RPM: 0.0056) / hsa-miR-624-3p (RPM: 0.1456) / hsa-miR-186-3p (RPM: 0.0884) / hsa-miR-2114-5p (RPM: 6.6774) / hsa-miR-194-3p (RPM: 0.633) / hsa-miR-3609 (RPM: 6.639) / hsa-miR-520g-3p (RPM: 0.0022) / hsa-miR-520h (RPM: 0.0012) / hsa-miR-10b-5p (RPM: 14052.6542) / hsa-miR-10a-5p (RPM: 408.7974) / hsa-miR-99b-5p (RPM: 14318.7458) / hsa-miR-6785-5p (RPM: 0.0412) / hsa-miR-6883-5p (RPM: 0.0016) / hsa-miR-670-3p (RPM: 1.3964) / hsa-miR-6849-3p (RPM: 0.0148) / hsa-miR-6732-3p (RPM: 0.1666) / hsa-miR-6733-5p (RPM: 0.449) / hsa-miR-6739-5p (RPM: 0.0102) / hsa-miR-619-5p (RPM: 1.5814) / hsa-miR-6856-3p (RPM: 0.0388) / hsa-miR-6506-5p (RPM: 0.1086) / hsa-miR-6733-3p (RPM: 0.0034) / hsa-miR-6876-5p (RPM: 0.0624) / hsa-miR-6130 (RPM: 0.0054) / hsa-miR-6129 (RPM: 0.0292) / hsa-miR-6834-5p (RPM: 0.0274) / hsa-miR-6873-5p (RPM: 0.0094) / hsa-miR-6829-5p (RPM: 0.0126) / hsa-miR-6813-5p (RPM: 0.011) / hsa-miR-6859-5p (RPM: 0.856) / hsa-miR-2392 (RPM: 0.0324) / hsa-miR-5587-3p (RPM: 0.089) / hsa-miR-6875-5p (RPM: 0.643) / hsa-miR-6734-5p (RPM: 0.3692) / hsa-miR-6763-3p (RPM: 0.0492) / hsa-miR-4707-5p (RPM: 0.0074) /
Involved Diseases
retinoblastoma /
Involved Pathways
Sequence
GGAAGTGCATCGGCCCCGGGTCTGTCCGGGCGTTGCGGGATTGGGGCCTGGGAACGCTCGGCCCCCGGCAGCCGAGAAGCCCGTGACTGGGCTGAGCAGCACCATCCCAGCCCTGGGGCCTGCTGACTGGTGAGGAACAGTGGGCGGCGTGGGGAGGGTCTTTTCTGCGCACAGGTCGCACCCCAAACCGCCGGTCCCAGATCACGGGTCCCCGATCCCCGCGGCCCAGCCCGGTCCTCCGCCCCTCGGCATCCTCTGGCTGAGACCCTGACTCCGGGTCTTTGCTCTAGCAGTAGCCGATCCCCGATCCCTCCGCCCCCCACTCGAGTCTGCCCAGACCCCATCTGGCCCCTGGCCCTCTTCGGTTGTCGTCCCGCAGTCCCATTCCGGAGTCTCCTGTCTCCGCCCCCCGAATTCCCGCAGCCCTCCCCGTCTCCGTCAGCCCCGGGTCCCACCCCCCTATCCTCTGGTGTCAACCCTGACAGCCCAGTCCCGGCTTCACCTGCAGCGAACCCGGAGCGTTGCTATCCTCCACCGGACTGTCAGGCTCTGCGCGCCCCGCGGAGGTCGGCGGCGACCAGCAGCGACTGCGGAGCGACGGCGGGCGGCCCCGGGCATGTACGCCCCCGGAGGCGCAGGGCTGCCCGGCGGGCGCCGGCGGAGGAGCCCGGGAGGCAGCGCTCTGCCCAAGCAGCCGGAGCGTAGCCTGGCCTCGGCCCTGCCTGGCGCCCTGTCTATCACGGCGCTGTGCACTGCCCTCGCCGAGCCCGCCTGGTTGCACATCCACGGAGGCACCTGTTCGCGCCAGGAGCTGGGGGTCTCCGACGTGTTGGGCTATGTGCACCCGGACCTGCTGAAAGGTGAGGGTGCTGCGCGCTGGCCCTTAAAGCCTCGGTGGGGGACAGAATGTGTTCTGGCTGAAGCAGAGATAGCCAGGGACCAGACACTTGGTTGAAGGAAACGGCCCCATAACTGCCTGGTGTTCATGCCCACCAGGTGGCTCTGTTTGGGGTCCGGCCCCTCATTAATTCTGATGTTATTCAGCTAAGCACCTACTCCTCACAGCCATGTTAATCCGGACTGCTGCTATTTTAGGATTCTGCTGGAGGAAGGACGCTGTGTATCGAGAAAAGATAAGGGTGCTAGGTATCACAGTTAGCTGGCCTCTTCTAAGGATCCTGTGAAATACGGAAAAGCTTCTTTGGGGCAGACTGATTAATGGAGAAAAAGGAACTTTTAATATGACTAGGTTTTAAAAGATATCTTAGAGTTCTATGGTAATCGGATGCGTATTAGAGAAGAAGGGAATCTGTGGCATTTTAGGTAATCGGAAGACCGTTCCATTGCCACCCGCAGTACAACAGTCGGAATGTGGCTCTTGGAACCATTATAGGTGTGCCTGACAGAGGCAAGGTTGCTTTGTTCATCATCATGCTTTCCGGCCAGATAGACAGCAGACGATGGGAGGGTCCTATGGGCCCCATAGTTTATCCTGCCCATTCTTGTCTCCAGTAAAAATTGTGAAGTGTGAGGACAGGACTGGACTGTATCACCTGCTTTTTACCCTAACAATGATCAATGTACCCCAAACAGTCCTTAGTAACAGCATAGTTCATCAACCCCAAGGTCTTTTGAGCCATCTTGAAGGTCTTATATCCTCTCTGTGCTATCCTGTCTGTGCTATTCCCTGGCTGTGATGCATTCCAGATGTTTACTGCACCGCCTATCAGAAGCACTTCCTGTTAGATATCTGCGTGTTACCTCCTGAAGAATTCAGGCACTGGGATTTGGTGAAAAGGTCCAAGTTCCCCGCTGTGCATCGGACCATACTCTGCTTCTGCAGGTCTAGGCTGAAAAGCCTCATCCTTGTGGCCAAATGTTGCCTTTCTCTGAGTGTTCTCTTACTGTTTTGCATCTCTCTTGAGTTTTAGAAGCTGTAGGGTGATTTTGTAGAAGGTTGGGGACAACTGGTTGTTTCCAGATTTCACCTTAATGGTACTCTTTGCTGGGTTGGCTCATTAAAGCCAAAGTTATGCACACGACAGAGGCCTTATATGCAGCCTTTTCTCTGTCATGTTGCTAATGGCACAAAGAGCATTAAGCTTGAGTGAGTCTTGGTGGTTTTTCTTTTAGCACATTGCCCTGTACTTGCTTTCTTTGAAGCACACATACCACCTTCCCACCACTAGACCCATCAGATCTAGAAAGCTAGATCTCCGAAATCTAGCACTGCATGGGGTGTGCTTAGCTGTGGCTCAGAAAAATGAAGGATCTCCCCAAGGCTACCCAGTTTAGGGTGGCAGAGCTGGGACTACCCCACCTCTGTTGATGCCAATATAAAATGATGCCGTGTCATTTATAGTTTTTATCCTTTGTTTTACTTCAGCTGTCATAAGGAGCAATCTCATAATTATTTCACTTTGGTGTGCATCCTTGTCGAAGGCATGTTAAAAATAAAAGTAAATTTTTGAGCCGGGCGTGGTGGCAGGCATCTGTAATTCCAGCTACTTGGGAGGCTGAAGCAGGAGAATCGCTTGAACTTGGGAGGCCGAGGTTGCAGTGAGCTGAGATCGCGCCATTGCGCTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCAAAAAAAAAAAAAAAAAAAGAAAGGCCAGGAACTGGCTCACACTTCTGATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATTGCCTGAGGTCAAGAGTTGGAGACCAGCTTGGCTAACATGGTGAAAGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGATACTCTGAAGGCTGAGGCAGGCGAATCGCTTGAACCCAGGAAGTAGAGGAGTTGCAGTGAGCCCAAGATCACACCACTGCACTCCAGCCTGGGCAACAGAGCAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAGTAAATTCTTGGTGCAGGTTCTTCTTTGTTCACATGTGTATTTACCCTTTCTAAGAAATTATTCGGGCCAGGCCAGGCATGGAGGCTCACACCTGTAATCCCAGTACTTTGGGAGGCCAAGGCGGATGGATCACCTGAGGTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCAACTAAAAATACAAAAATTAGCCAGGCCTAGTGGCTGGTGCCTCAACTACCCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGAGGTTGCAGTGAGCCCAGATCACACTACTGCACTCCAGCCTGGGCTACAGAGTGAGACTCCATCTCAAAAATTAAAAAGAAAGAAATTATTCAGGCTCCGTTTTGTCTTTTGCAAAGCATGTTTTCTTAACCTTTACATTACATTTGCTCACATATTTAGAGACCTTAACCTGTGTATAGTTTCTACTTGCTTGCCTGTGGCCATCTCCTAAGAGCAGTTTGTGCCCATTAATAGGAGAGTTGGCAGTGGTGCCTCATGAGCTATCACAGAAGAATCAGTAAGGAATCCGGAAGTCCTTGATTGCATCTTCTCTCCCTTTTCTTTGTACCTACTGGTTTTTTGGTACCCAGTGGGCCTTCAGACATGTAGTATCCTGTGTGACTGTGCTGATCCTCAGGGCCTAACAGATATCCTGACCTGAGAGCCTGGAGTATTCCACATCTCAAGAGGGAGCAGAGCTGTCAAGCACAGATGTGGTGCATATAGAGTTTTTTTTTTTTTTTTTTTAAATGAGACAGACTCTTGCTCTGTCACCCAGGCTGGAGTGCAGCGGCGCCATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGTCTCAGCCTCACGAGTAGTTGGAATTACAGGTGCTCCACCATGCCCAGCTAATTTTTGTACTTTTCGTAGAGATGAGGTTTCACCTTGTTGACCAGGCTGATCTCAAACTCCTGACCTCAGGTGATCCACCCACCTTGGCTTCCTAAAGTGCTGAGATTACAGGCATGAGCCACCGCTCCTGGCCACATGTAGATACTTCCAGAGGGAGAACAGACCCTGCCAGGTCTCTGCCGGTGATGGGAGTTGGGCAGCCAGCAGGCCCTGGAGCAGCCTTACCATTTCTCAGCCCCTGCCTGAGTGCCACATTTTGACATTATGCTAAGCACACCCCATGCCTGCTTTTTTCCTCCTAAACAGCATCTTTATTTGGTAGGTACTGTTTCAGCCCCACTTCAAAAGGTCCCAGCTCAGGGAAGCTAGGTAGTTTGCTCAGCTAATCTGAGTGGACATTGACTCCAAAGTCCATACTCTTACTGCAACACCTTAGTGAGCTCCGAGTTTATTTCCCATCAAAGCTGCCTGAGGCTTATCACTTTCCTATTCTAGTTGAGTTTTATCATAAGCCCAGCCAAAGCTGTGCTTTTTGTCATAACTTCATCGCCTCAGTGTTGAGGCTTTAGTTGGTGATCCCAGGGCAAAGCCACTCTCCCATTGTCATTCACAAAGCTTCAGAGGCTTTAGCCAATGAAAGCTGGCTCCAAAGAACCCATCCTGGGCTGGGTGTGGTGGTTCACTCCTGTAATCTCAGCACTTTGGGAGGCTGAAGCAGGAGGCCAGCAGGATCACTTGAGTCCAGGAGTTCAAGGCTGCAGTGAACTATCGTCGTGCCTCTGCACTCCAGCCTGGGTGACAGAGTGAGACCCTTCCTTTAAAAAAAAAAAAAAAAGACCTCATCCTGGGTTTTCTCCACTGCCCCTGCAAGCGGTGCCTGCTTCTCACACAGCTCTCAACCTGGCCCTGGGTGGAGATAGACTCACACCTCTAGACCCCAGAAAGAGGGGCCGCAGATAGTCATTTCTTCTGAGCCTTTCTGCCTCTCAAGTGTGGCCACCAAAGGGCACTGGCAACAGCCCCAGGAAGCATCTTTGGAGAATGAGGAAGTTGGGGAGTAGAAGTCAGGTGAATCACAATTGACAGCAGCCACTGGAAGATCAAGGGCCTTCCAGGGAGAGCCTGTGTGCCTGATAGGTGGTGACTGGGGCAGCTGACACTGCCAGGCCCTGCGGGGCCTGTTGGTGTCTGTGGGATAACCTGGCTGGGCACTAGAGGGCTCTGTTAAGAGGCCTGTGTCGCAGGCCTGTCTGGAAGCTAAAAAGGTCACAGTGAGGAGACGCTGAGCAGGTTGCACAGATGCATAAAGAGGGATTGGGGCATTGGGGAAGTGTCTCTAATTCAGAGGGACTCCAGCAAGAAGGGAGGCGGGGTGGGACAGAAGTCCTTTTAAGCCTTTCTGCCTGCAGACTGTTTGGGTCAGGAGTGGTTAGAGCAATGGGCAGATAGACAGGAAGAGGCAGGACCTTCAAAACAAATCTAGCCTGGTGACTCACCAGTGACCTTGAGCAAAGTCAGTTCCATGGGATCCTATTACAGCTGCCTACTTCCCTGATGACTAGAGGGCACCGCCAAGCAGTGTTTACCAAAATCAACAGGCCAGAGCACAGCTGGAAGGTAGGAGGTGTTCTGTGTCTAGCCAGGGCATCGTGGACTGCACCACTGGCTTGAATTTCAAGTTAGGGTCCTGCGTTGCATGCCATTTCTCTCTCGAATAAAATCCTACATACATAACCTTCAGGGGTTTTCTTTAGCAATCCCCTCATGGGAGCAGGTGCTTGTTGCCTTCCCTGCTGTACCGACGTCTAGGAAGGGAGGAGAGAAAGACATTGAGATACTGACTCCAGAAGAGTCTCTGAGCTGGGCTCCAAGCCTGTCTAGGATAACTGCCTGTTCTTCCGGTGTGCTCTGAGACCCTCTGAGGAAAACCCACCTGTTACATGGGGCAGGCCCCTGGGGTATCTGTTAACGTTACCCAAAGGGAATTTCATATTTGGTTTTCTCACTAACCCTGAGGGTTTACTCACAGCTTTGGAGTGGGGAAAGGCAGTTATATTGAAACAAAACCTATTGGAGTTTTAGGTCAAAAGTCTCTTCTCTCTATCATATTGTCATACTTGTAGGGTAGGCCCTTAGTCTGGCTTTAGTAGGCCTTGGTCCACACGGGCTGACGTGTGGTCAAGGAAGTCTTGGTAGAAGAAGGAAAGGCATGCTGAGGTGACACACTGGCCCAGCTGAAACAGCCTCTGGTTAATAACAGCACAGGTGGCTGCTCTTTCATGGGCACGGTGTCAGCTGACCCAGCATGCCCTGGTGGTGGGTGGGGCAGATGTTATTGTTTTCATTTGATAGATGAGAGAACAGAGGTCCAGCGCACTCAAGGGACTTGCTCAAAGTAACACAGTCTCTGCTAGAGCTAGGATTCGGCGCCAGGTCCCAAGCCTTTCCGGTGTCCTGACCACTTCCTAGAGCAGGCTCTGATGGTTGCAATGCTGCAGGAGCTTAGACACCATGCCTGGCAGGTTTTGCCCAATAATTCCCCATGTGAGGACTTAATGACCCAAACCTTTTTTGCTTCTTAGAGAGATTTCATTGCTTCAAGCTGTTCCTCTAGTGAGCTTAGCAGCTGGCTCTGAGGATGGCTCCAACAGTATTCCTGTTAGCTTCTGACCCCTCATTCACGCACAACTCTTTAGGAATTGATTGATTATCTCCAGGGAAAAATACAGTGGCCGAGTCTGGTACTTAGTGATTCCGAGCAGCACAGTGTAGGGGAGCCTGATCATGGTTTGGAATCTAGCTCTGCAGCGTGTGGCCTGGAGGAAGCCACTTCACCTTCTGGAGCCCCCGACTCCTCATCTGAGCTGTGTGGTAAATCCCCCAGGGGGGCACTTCACCCATCTGTGTGCACAGGCTGTTCCAGGAGGGGTATACAAGGCCCCTCCAACAATATTTGCCTTTGGAGAGGAGCAGGTGGACATCCGCAAGGGGAGGGATGTCCTCTTGGAAGCTTTTTATCATGTGCATGTCTCCTTACTAGTAAAATTCATGTATAATGAAACATAAGACAATAGGAGTATATGTCATGGATGTACATTTTTAAGGATAATCAAATGAACATCCTTGTGCTCACCATCCAGCCAAAGAAACAATACAGGCTCCTTGAAGCCTGCACATATTACTTTTCTTACTCCAACTGCCTGGCCTCATCAGTAATGTGAGTGGAATCTGACACGGCCTACTGCAGAGCGGCATGTGACCTCTGGTAGGTTATTCTTGGAAGCACTATAAGAACACTGCCCCATCCCTGCCACATGCCACGTGGACCCCAAGAAGAACTCTCTTAGCTTTTAATAAGATTTAAAATACAGCCAGGAGATAGCCCCTGTCTCCTAGAGCTTTTCTTTCAGTGAGGCCCCATGCACTATGGCTCTGCAGGGCTGGGTTCAATGAAGGCTGGTCCCAGTTGCTGGCAGGGTTCACACACAGGCAGGCTTTCTGGCAGTAGACAGTTACCCAGGCTGGATGCTTGGGCCCAAAACAGATGGTCAGCAGACAAGAGATCATGACAGATAGTTCTGAGGGCTGCTTCGTGGGTGACCCAAAGCCAGACAGAGGTGTATGAGCCTTGTCTGGGCCCAGCCAGCCTCTGCTGGGCGAACTCTGAGCCTGAGGCAGGGTATGCGTGCTCAATCCTAGAGGCTCAGGGCTTCTCTCTACCCAGAACCTGTGATGCTGGCATCTGTTGGGCTGAGTCAGCTTTGCTGGGTTTAGGTCCCCTCCCCAGGTTCCTGGACTTTCCCCCATCAGTCCACCTTCCTCTGAGGTCTGGAACCAGTGTTTCTTGAAGTGTGGGGCTTGGATCACCTGCATGGGGATTACCTGGGCTGCTTGTTAAAATCCAGATTCCTAGGCCCTGCTCCAGACCTAGAACTCGGACTCTCTGGGGACCTGGGAACACGCTTTCAGCCAGTGCCACAGTGATTTGGGTATGCCCTAGAGATTGATGATCACACCCCACACCCTCTCAGCCTGAGATCAAGTTCAGGAAAGGACGCTATATAGCCTGAGTCTTGCCAGCCCTTTCCAAATTTTCCTAAATCACTTGGTGACCCATGGCCTAAATAAAAGAAGAACTTGCCAGTGGCTGTAACAGAAGAAGGAGAGGAAGTTAAGGCCCATTTCCTACTTTTTTTTTTGAGGCGGAGTCACTCTGTCACCAAGGCTGGAGTGCAGTGATGTGATCTTGGCTCACTGTAACCTCCACCTCCCAGGTTCAAGCAGTTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCACGCCACCATACCTGGCTGATTTTTTAAATTTTTAGTAGAGACAGGGTTTCACCATATTGGTCAGGCTGGTCTCAAACTGCTGACCTCAGGCGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCGACCCCATTTCTACTTTTTATGAAAGCTTAAAATACTTAATCATGGCCTGGTTTCTTTTTGGTTCAGCCTTTATTCTACCCTATGCTTCTGGGAGCTTTTGCAGTTTGCATAGTTATCAAAGGAGACAGACAGTATCATCTAGTTTTTTGTTTTTTTGTTTTGTTTTTTGTTTTTGAGATGGAGTCTCGCTCTGTCGCCAGGCTGGAGTGCAGTGACACGATGTCGGCTCACTGCAACCTCCGTCTCCAGGGTTCAAGCGATTCTCCTGCCTCAGCCCCCCGAGTAGCTGGGACTACAGGCGCGCGCCACCACGGCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCACGCTGATGTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCCAGGATTATAGGCGTGAGCCACTGTGCCTGGTAGTGTCGTCTAGTTGAAATGTTTTTTTAAAGAATGGCTAAAGTACTGGAGGGAAATACAAGTTGCTGTGTGTCTGCTGCGTGGTTGTTGTCATGGGCTCTCCCTGCACCATGACCCCCAGGAACCCCTTGAGTGCTGTGTCTTTTCTTTCAGCCTCTTCCTTTTCCTTCATTTATGCCCTTGACGTGTGCACGTTGGCACTGTCCAAGGCTTCTGGGGCTTTTGTGGTATAAATGTGGTGGCTTCCTAGCTTTTCCTGTTGATGGCTTGTCCCCAGCTCTGCCGAGTCTGCTGAGTCCCTTTTAGGTAGGTCTATTTCCCTTTACTTTCCAGTTTTTGGAACCTTGTTTTATACCTCCCTTTCTTTTTGTGTGGGTTGCCTTTTAAAAGAATTCTTTTGTTCTCGTAGAGTTCAGGGAGGGAGCTAAACTAAATGTGATATAGTCTACCAACTTTCCTAATCTATGTAATACTTTCTTGTAGCTGCACATTTCTCTAAACTGCCGCAACTTCCTTCTTCCTCTTTTCTTTATTTTACTTTTTTTTAAAATTGTGGTAAAATATACATAACATAAAACTTAGCATTTTAACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCTCTCTTGTTGCCCATGCTGGAGTGTGAAGGCGCAATCTCGGCTCACCGCAACCTCCATCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATCACAGGCATGCACCACCACGCCCGGCTAATTTTGTATTTTTAGTAGAGACAGGGTTTCCCCATGTTGGTCAGGCTTGTCTCAAACTCCTGACCTCAGGTGTTTTGCCCGCCTTGGCCTCCCAAAGTGTGGGATTACAGGTGTGAGCCACCGTGCCCTGCCAACATTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCAGGCTGGAGTGCAGGGGTGCAATCTCGGCTCACTGCAACCTCCACCTTCCGGGTTCAAGCAATTCTTCTGCCTCAGCCTCCAGAGTAGCTGGGACTACAGGCGCATGCGATCACACCCAGCTAATTTTTGTATTTTTGGTAGAGACGGGGTTTCACCATGTTGGCCAAGATGGTCTCGATCTTCTGACCTCGTGATCTGCCCGCCTCGGCCTCCCAAAGAGCTGGGATTACAGGCGTGAGCTACCATGCCTGGCCAATATTTTGTTTTTTTAAGAGACAGGGTCTCTCTCGGTCATCCAGGCTGGAGTGCAGTGGTGTGATTATAGCTTACAGTAACTCCTGGGCGCAAGCAGTCCTCTTGCCTCAGCCTCCTAAGGAGCTAAGACTATAGGCATGCGCCACCATGCCCAGCTAATTTTTTTTTTTTCCTCAAAGAGACGGGGTCTCACTATGTTGCCCAGGCTGATCTCAGACTCTTGGCCTCGAGCAATCCTCCTGCCTCAGCCACCCAAAGTATTAATAACCATTTTAAGTGTTGAGTTCATTGATATTAAGCACATGCATCATGACTATCTGTTTCCAAAACTATCATCATTTCAAACTGAACCTTTGTGCACATTAAATGATAACTTCCTGTTCTCCCCTCTCCCTACCTGCTGGCAACCACCATTATATTTTCTGTCTCTATAAACTGATTATTCTAGGTATCTCATATGAGTGGAATTATAAAATATTTGTCCTACATTTGGTTGATTTCACTTAGCATAGTATCTTCAAGTTCAACTTCTTTTTGGAACAAAAAGGGAATGAATGAGTGAGTAAATGGAGAATCAGCATTAATTGACCTGTATGGTCTTAGCCTCTCTGGCTGTCTCAGCTCCAAAGTCAGGCTTTTCCTGCCAGCTCAAAATATCCTTTAGCAGAATGCATTAACATGTCAGGTTAACTGTCAGTGTCTTTAAAAATGGTTAGAAGGGCATGGCATACACAGTGAAGTAGAATCCTGCACTTAGGCTAGTCCTGTTGGAAAGAGAAGGACTTGAGGTACAGGAGAGCAGTGGCCTCTGCTAATGTGGAATTTGCTCCAGCTACCCTGCAGACCACCCAGGAGCAGGGGCTAAGACAGCGTCCTCCAGAACTGCCCTGGCTCCCAGGACTGTGGTGGAGGGGAATCAAACTCCTTCTAGGTGGGGACTTCCTGCACCAAGTGTTACTTGGGGCCGTGAAAATTTGGTTCTCCCTCTACAGATTTCTGCATGAATCCCCAGACAGTGCTGCTCCTGCGGGTCATCGCCGCCTTCTGTTTCCTGGGCATCCTGTGTAGTCTCTCCGCTTTCCTTCTGGATGTCTTTGGGCCGAAGCATCCTGCTCTGAAGATCACTCGTCGCTATGCCTTCGCCCATATCCTAACGGGTAAGCCGTGAGCCTGCTCACAGTGGGAGAGGAACTGCTACAGGGTGGGGGCATCCTGTCTGAGTTGCCGGTGGGGGCTCTGGTTTCTCTGAGCAGGCACCCTTCCAGGAGCTCATGTGCCAAGCTCCAGTCTTTCCCAGAGTGTCAGGGTGTCAGCAGCCTGCTCCAGTCTAGCTGCTAACTTGCCAGGATCACAAACCCACTCAGCCCAGCTGTAGAGGGGAAATGTTGCTAGAAATTCCACAAGGAAGCTCACAGCTCTCTAAAATGGCATTTGAAGCTCAGACCTGACATGAGTGAAGAAGGAACCAGGCAGTCTCCCGTGTCTCCCCTGGAGCTCCTGGTCAGATTCTCTCCTCTCCACCTTCCTGCTTCCCTACAGACCCGCCTTTTCTTGTATGTAGCTGCTGTCCTCCCTCGTGCCTGCACTGCTGTGCTGGTTTGAATTGTGGTGTGCCTACTCCAGCTCCCAAGCTGCATGACCCTATTTGCTCCTTAAGACAGATGGAATCTGACTGGCCTAGATCAGGTCAGACTGCTGTCCCCAACCTCAGGCCAGGAATCCCATGGTCAAGAGAGCTCCTCCTTGCAGAGTCTGGGGCCAGGCAGGTTCTCTGAGAATGGGGTTTGGGTAGAGAGGCTGTGATTGGGTCCTCAAGCATCCTAGCTGTGGAGTGCTCACTAATTCCCCTTCTGTGCTGTCCCTCTGTCTCCTAGTTCTGCAGTGTGCCACCGTCATTGGCTTTTCTTATTGGGCTTCTGAACTCATCTTGGCCCAGCAGCAGCAGCATAAGAAGTACCATGGATCCCAGGTCTATGTCACCTTCGCCGTTAGCTTCTACCTGGTGGCAGGAGCTGGTGGAGCCTCAATCCTGGCCACGGCAGCCAACCTCCTGCGCCACTACCCCACAGAGGAAGAGGAGCAGGCGCTGGAGCTGCTCTCAGAGATGGAAGAGAACGAGCCCTACCCGGCGGAATATGAGGTCATCAACCAGTTCCAGCCACCCCCTGCTTACACACCCTAATGCCAGCCCTGGGCTCTCTTCCTCGGCAGCCCCTCCCTCAACTCTGCAGCTCCTCTCGCACCCAGAGGAGCTCCTTTCCCCAGCAGGCCTCACTGGTAGGATCCTGACCATCTTCTCCAAACCTTCCCCAGGAGAGACTCTGCCTTTAGGGTCATCCAAGTATCCCTGCTCTCAGAACCGGAGGTCCACTGGTTTTCTATAATGTACTCTTTCCCTCCTGCCACATCCTGCCCCCTTCACATTCACGAGTCATTACCAGCCAGGGAAGGTCATCCAAGTTTCCTCCAGCATGGGCGATATCTTTGGGACCGAGACTTTCCTTGGAGAGCTGCTGAGAGCGGACAGTCCCAAAAACAAGTGTCAAAGGGCCCAAGGGAAAGGGGACTGTGCCCTGGAGGCTCACTTCACAGGGATCAGTGTTTGCTCCACAGCTGTAGCTCTGGGCTGACGCCCCCCAGACCCCTTCCTTCTCGGAGTGACCCGCCCCCAGGCCACCTGCTCCGGGGAGTTCTGTGCACTTTACTCTTTGGACTTCTCCTCACGTGTGCCCTGGTTTTATGGGGAGAGGGAATCGCTGTTGGGAAGGCAGAGCAGTTGCAACCCTCTCTGCCCTTGCTTCATGTGGCTGGAGCCCAGGCAAGGAGAGCAGGAGCCAGCGTGAGACTGAGGCCCCCTGGTGCCTATCAAGGACCAGAGTGAAGGGGACTACATCTCCCAGCCCTTCACCTTTTAAATATGAGTGGTTTTAAAAGGAAAAAAATGAAACCAGGCAACAGCAACAATATTCTGTTTTTAAAATAGGGACAAGACTGTTGTCACTTTTTAGACATGTATCCCATTCCTTTTGGCTCTGCAATATTTGGGGCTGTAGCTCCTTCCAAGCCCATGGTAGTCCCTCCCCGAGTCTCTCCCAGTAGAATGCAGCCTCCCTTCCCTGGCCCCTTCCCTCTCAGTGACGGTGACTCCCTGGGGCCTTCTCGTGGAACCCAGAGGGGCTGAGGACTGTGGCCTGGCTGGCGGGCCAGCGTGGTGCTCCTCAGGACTGCAGCACTGAGATGGAACCTGGCCTCAGTTTAGGAACAGGGGCCACAACAGGGCAGGAACCCACCACCCTCCACATAGGAATACAACCAGTGGGGCCACATCATGTGAGGCATCAGACCCACACTGTCAGCCCAGCAGGCCGGGCTGTGTCCTTCAGACCCAGTGCTGCCCTAGACTCTGACTCGGGACTCCAGCTTGCCACGTGCCCTCTCCCCTCTTGAATGTACTCTGGTCTTGCAGTGTGCTGCTGGGACTTTCTTGCTCAGCCATCACTCTGGTCACCTTGTTTGCTCTGGGTCTGGCTGAATTTTCTGCCCTGAGATCTGGGCATAAAGTGGATGAAACTTGAAAGACCTTCAGTGTAGATCCAGATGGCCAACCTGTCCTTGTTAAGTTACTTGCTTCTTGGGAATCAGTGTCCCCTGCTGAGCTGAAAAGGAAATGGATTCCAATCTCTTCCAACCTTTAAGGTGATAGATAGTTTGAGCAAGACTGGAGAATGGACAACACTATGAAGCTGTGGCTAGAAAGGGACTGTCATGTCCCATCCTTTGGCCAGATTGACTGGGGATGTCCGGACAGATGCCTGCATGGGTGGTGAGGGCCACATCTGCACACGAGCCAGTGGCTGCTTGCAGTTCACTGCTGTGATGCCAGAGTGTGTTCAAAGGTGACTCTCCTGCTCTTCTGGACTCTTCTCTCAGGCAAGAAAGGCTGCAGGCTGCCTGCTATGTGATGCCTGAGCACAAAGCCAAGGAACTGAACTAAGTCTTTCTGTTAAGTCCTGAGTTTGTCATTGGCAGGTTTACTTGTGGCCAGCTCTCTCTGCCCTTGGGTGTCTGAGCAGGCAGACCAGAAGACCAGGCACTGGACCTGCATGCCAAAGGGACTGGTCATCTCCTGAGGACCTGTAAATGACCCTGTGGACTGTTCCGCACGATCCGGAACCCACTTTTTATTCACTCCCCATGTCTTTGGCCTTCCTCTTCTTTCTCTTTCCCTCTGCCATCCTGACACTGATAGTTTGTCATATAAATTCCCCGGGTTGTGTTTTTTTTTCTAGAAAAAAATTAAAAGGGAAAACAAAACCAAAAAAACCAGAAACCACGAATAAGAATGGAAATGACAATGGCTGCCTGTCATTTTTCTGTCACGATTTTCCTGATTTGGTTTGTTCCCTTTGTCTCAGAGAAGCAGGAGATGTTGATGAGGCTGTATTTTTTTTTCTTTTTCTTGTTTTTGAGACAAGAGTCTCGCTCTGTCACCCGGGCTGGAGTGTAACGTGGCATGATCTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTATCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCGCCACTATGCCCAGATAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTGGAACTCCTAACCTCAGGTTATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGCATGAACCACCGTGCCTGGCCAAAGATGTAATTTAAAATAGTTAGAAGGGACTTGGCATGGGCCAGCTCCGTGCATGGCATTTTCACCCCCAGAGCTTCCTAATCCTGTTTTCACACAGGAAGTTTCTAGGTCTTTCTAGAACAGCTAGAAATAGTAGCTGACTCCCGCCCAAGGCCCAACCTTCAAACCCTGAGCTCTTCAGGCTGCATCCTCTGGTGAGCTATAGAGGAGAACGTGGCTCCTAAACTCTAGCCATCCTGTGGGAGGAAATAGACTTCTTTGGGCTGTGGCTTGCAGAACAAACTACACTTTTTTTCCCTCTATTGTTTAAATTTTATTTAATAATTTGTGTGTTTTTCTGTCTTTATTTTCTGTATTTCACGTGTTCCTTCACTCCCTAGAAACTGCACTTTCTTTGAAACCATAGGTAATGAATCTTACTAGGAGAGGCATGGGGATAGAGACAGTTCTGGGAGTGTGACCTGTAAGCCTCCTGTAGGGCAGTGCCAGGCCTTGATTGCCCACGTTCTCTCCGTTCCTTCTTCCTTCATACATTTGATCACACAGCCTACACCCAGCCCCGAGTGTGCATCACGGTAAAAGAGCTGAGGGCTCTCTTCAGGGAGCAGCCCATTTAGGTCTCTTTTGTTGTTGTTAGGGAGAATACACATCTTTCTTGGAAGCTGGGAGTGTGTTCTCATTTCATGTCCATTCAGACAAAGCACCATTAGGCACCATGAAATATACAGTGACGGACAGGACCCTGTCTGCAAGGATTTTATGTCCTTAGTTCAGGAGATGGACTTGTCCACAGAAAGGCAGAGTGAAGTGGGCGGCCGGCTCGGAAAAGTCCTGTGCCCAGAAGGGAGCCAGTTCTGACCTGAGTGATAATGAAAGGCTTCCTGGAGGACGCAGCTTGAGCCACACTTGATGTGGGAGTGAACTGGGATAGGGACACTCCTGCTGAGAGAATGGCAAGAGCAAAAGCACACTGGTGGCCAGGAGGTGGTAAGAGCCGAGGTTAGAAAGGTGAGGGGTGCTCATTTAAGGCACTAACAGCAGAAGGAGCCCAGGAAGGATTTTCAGAAGGGAAGGGAGGGATGCAACCTTATTTTAATGACTGGTGACAGTAGGAAGGGTTCTGCCTGGCCTTAAGTGAGGGTGTTGAAAGTGGGAGACAGGACCTGCCAAAGGGGAAGAGGGCGGTCACAGTCAATCCCAGGGCCCAGTGTCTCAGCCAGGTGCTGGAGTTGGGAATGCGGGAGCCCCAGTCTCTGCCCACCTGTCACGTGGCAGCTGGAAGGTGGCATCAACTGCACAGGCGAAGAGGGGCCCGCACACGAGAAGCCATGGGATGTGAAGGGCCGCAAGGAGAGGACCCTGGGACACAGGAAGAGGTGGTGCATCTGGGGCAGGGCGGCTTTCCCAAGATGACTAGAGAATCTTCAGCTGGCATCTTGCCTGAAATATCCACGCTCTCAGCCACTACACTAATGGAACACAGATGCTATGGGGAGACAGAAGGGAACTGACAAACTTCATGCCCCTGTTTTCAAATAGCCTGCAATCTTACCTCTTCCTCTGCATTTTTTGGGGGGAGTGACATTTTAATGGGAGGCAGGAGGTTTGTGGAGAAGAGAAAATGTTTTTTTTGTGGGGGTGGGTAGAGACAGTCTCACCATGTTGCCCAGGCTGGTCTCAAACTACTGGCTTCAGGCAATCCTTCTGCCTCCCTTCCCAAAGGGTTGGGATTACAGGCTTGAGCCACTGCACCAAGCCTGAAAATGTCGTTTTGAATGAGCCCACCTGAAACGAAGACGCTTCATTAGGGTTACTGGTTTGAGAATTAAGATCAGTTCTGGCCGGGTGCGGTGGCTCACGCCTATTATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAAGGTCAGGAGATCGAGACCATTCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAACCAGGCATGGTGGCAGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCATGCCACTGGACTCCAGCCTGACAGAGTGAGACTCCATCTCAAACACACACACACACACACACACACACCACACACACACACACAGGTTCCTCACCATAAGCTTTGGGGAAAATTCTTGGCTTTTTTGCTGGGGGAGAGAGCAGTGCCCAGGGAAGATTGGCTGATCTCAGAGCTGGAGGGTTTATGCGGGACTGGCCAGCCCCTTCAGCTGAGTGGGACAGCAACACAGTGGGTGGTAAGGGGCTTCATAAGATGTACAAGATGAGGGAGAGGCCCCTCCAGCCAACCCTGTGTCTAAAGAGTCAGGTAACGAAGAACTTTCCAGAGACAGCTGTGAGTCCGTCTGGCTTAAGGGGTTGTACAGGTGTCTGAGAATGGGGCCTGAAGGTGCAGGGCCTGCAGGCTGCCCTGTTTGGAAGGTTCCTGTCCTTCTGTCTTGGTAGAAAATGGCAGCTAGCCTTGTAAAGGGCCTCCTTGTGTAGCGAGATAGACCATGTAGCCCCAGATGCCCCCATGGCTTCACTTCCCTCTTGGGGGTCTCTCAGTATATGTCTAGTGCCACCACTATTGGTGGAGAGTTTCCTTCTGGAATAACCTTGGGGTGGTGGATGGGTTTTATTTTAATAAAAGAAGAATGTCTCATTCA

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