Details for gene: RASSF1


This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]


Symbol
RASSF1
Name
Ras association domain family member 1
Entrez ID
11186
Ensembl ID
ENSG00000068028    (more details)
KEGG ID
hsa:11186    (more details)
OMIM ID
605082
Uniprot ID
Q9NS23  
GO ID
hsa:11186    (more details)
Chromosome
3
Strand
-1
Start
50329782
End
50340980
miRNA Interactions
hsa-miR-124-3p (RPM: 4110.4386) / hsa-miR-205-5p (RPM: 5027.3352) / hsa-miR-1291 (RPM: 2.2386) / hsa-miR-19b-3p (RPM: 197.0578) / hsa-miR-129-2-3p (RPM: 79.8688) / hsa-miR-186-5p (RPM: 1645.2832) / hsa-miR-130b-3p (RPM: 68.2014) / hsa-miR-497-3p (RPM: 0.4852) / hsa-miR-373-3p (RPM: 0.0958) / hsa-miR-203a-3p (RPM: 1346.5646) / hsa-miR-181b-5p (RPM: 3069.8278) / hsa-miR-181a-5p (RPM: 52364.6344) / hsa-miR-21-3p (RPM: 238.3548) / hsa-miR-1-3p (RPM: 26.3428) / hsa-miR-744-5p (RPM: 290.9362) / hsa-miR-27a-5p (RPM: 7.3838) / hsa-miR-126-3p (RPM: 494.5936) / hsa-miR-210-3p (RPM: 361.0562) / hsa-miR-191-5p (RPM: 12993.8088) /
Involved Diseases
retinoblastoma /
Involved Pathways
Ras signaling pathway / MicroRNAs in cancer / Pathways in cancer / Bladder cancer / Hippo signaling pathway / Non-small cell lung cancer /
Sequence
CTTCGGGCCCCACAGTCCCTGCACCCAGGTTTCCATTGCGCGGCTCTCCTCAGCTCCTTCCCGCCGCCCAGTCTGGATCCTGGGGGAGGCGCTGAAGTCGGGGCCCGCCCTGTGGCCCCGCCCGGCCCGCGCTTGCTAGCGCCCAAAGCCAGCGAAGCACGGGCCCAACCGGGCCATGTCGGGGGAGCCTGAGCTCATTGAGCTGCGGGAGCTGGCACCCGCTGGGCGCGCTGGGAAGGGCCGCACCCGGCTGGAGCGTGCCAACGCGCTGCGCATCGCGCGGGGCACCGCGTGCAACCCCACACGGCAGCTGGTCCCTGGCCGTGGCCACCGCTTCCAGCCCGCGGGGCCCGCCACGCACACGTGGTGCGACCTCTGTGGCGACTTCATCTGGGGCGTCGTGCGCAAAGGCCTGCAGTGCGCGCGTGAGTAGTGGCCCCGCGCGCCTACGAGAGCGGAAGGGGCAGCCAAGGGGCAGCGCAGTCGCCGCGGGTCAAGTCGCGGCAGAGGGGGTCGGCGGGGACAGCTCCCGAGGACTAGGTCCGTTACTTTCGCCCCATCGCTGAAGAGTGCGCGAAAATGGTTTATCCCTTGTCGCACTCCACTCGTATCTGGGCCACAGATGAGCAGAGGTGGCTGCTTATATGTAAAAATACGCTGATTTTAAGTTTCTTATCTTTAAAATGCCTTGGCCCTTCTTGAGAAAGGGTTTGTGCCTACTGTCCTCGGAGTCCATCTTCCCAGGCTTGCCTCTTCTCAAACACTCATGACCCCCTCCAGAACCTTTAGGGTGAAGGGAAATTACCACCTATGGGAGGGAGCCTGGAAAAATTTAGAACCTTTGGTGGGCCCCCTGCAAGCAGGAGTTTTGTTGAGTCTTTATTTAGCAAACACCCTTTTCTGACCCAGTGAATCAGATGCTAAAATATGCACGCAGCCACACACCCAGCAGTCCTTCTGCACCCCTGGGAATCGCCAGCAAGCAAAGGTTGCTCTCCCCTGGGTAGACACCAGCTGGAATCACCAGGGGTGCTTTTACAGTCCTCCCCGCTAGCCTGGATCCCACCGCAGACCTGTTGAATCAACTGCTGGGAGTGGACCCTAGGCATCAGTAAATTTTAAAAACTCCCCAAATTATTGTAACATGGAGTCTGGGTTGAGCATCACTGCTCTGGCCTATTTAGGAACTTGTGGATGGATAGTGTCCCAGGTCTGTGTGTGCATGGAGACCCTCTCATCCGGTACAAGAGGACATCACAAATTCAGCTGGGGGGAGCACAAAGTTGTGACAGAATGCAAAGAATGAACAAGGGGCCGAGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTCGGAAGGCGGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCTCATGTCTACTAAAAAATAAAAAAAAATGAGCCAGGCGTAGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATTGCTTGAACACAGGAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCCCTCCAGCCTTGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGAACAAGGCTGGGACATTGCAGCGTTCTCAAAGAGAAATAAAGTAGCCATGGAGATAAGAAGCAGGATGATTTGGGCATGTTTATCAGAGGTAGAGACAAGGGAGAAATCAAAGATAAGTTTGGGCTTTTGTCTCCAGTAACTGGGAGCCTAGTGGCCATTTTTGCTGCAAAGAGGAAGCTGGGCAAGTGTAGCAGTGAGGCTGAAGAAAAGGGAATTAAATTTTGGCCATGTTCACTTGAAACGTCTTTTAGACATCCTAGTGAAGGTACTGGCACGGAGGATCTAGTCTGAGGGTTTAGGTCAGTGTTTCAGCCGTGGATCTGGGGCAGATGAATGTAGACAGACCAGGCCAGTGATCAGGACTGAGCCCAGACTTCATCGTGAGATATGGAAGTTGAGTCAGAATCTGCAAAGGAGCTGAGCAGGAGCTGCAGGGGGTAGGAGGAAAACTGGGAGAGTGTAGCCCCTGGGAGTCAAAGGGAGCAAGCTTCAAATGATGCTGAGGGGGTGAGAATGGAGAATGGAACACTGGATTCCATTTGGTAGTACACAGATCGCTGAGGACCCTGTCCCGGGCAGTTTCCTGGAGGAAGAGGCAAGCCTGGCTGGAGTGGGTAGAGGGGAGAGTGAAGGCGAAGGATTAGAGTGTATAGAGACCAGTGTCTTGGTCTGAGGGGAGTAGAGACAGGTGACAACCACAGGGCAGACGTAGGTTAAAGGTGTTTAGTTTTTCCTTCAAGTAAATGGGCAGATGTATTCCATATACGTTCCCAGTGAAGGGCCGGGTGCGGTGGCTCAAGCCTGTAGTCCCAGCACTTTGGAAGGCCGAGGCGGGTGGATCACCTGAGATCAGGAGTTTGAGACCAGCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGCGGGCGCCTGTAATCCTAGGTACTCAGGAGGCTGAGGCAGAAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGCCGAAATCGCGCCATTGCACTCCAGCCTGGGTGACAAAAGCAAGACGCAGTTTTTTGTTGTTGTTTTTTTAATTGCCAATGAGGAAAGGGGAAGTTCTGTGCTAGGCGATAGAGATCCAACTGTTGAGCAGGCCTCTCTGCCTGTGGCCTTCCGGCCGGTTTCCAGACGCCCAGGTGGCCAACATTAGAGTCCGCGTAGCAGTGTGAGGTAACCCACTGAGATAGGTCGGGCCTGCGGAGCCTGGCGAGCAGCGGCCCTCTCCCTGGGGCTTCCCTTCAATCTCCGGGACATTTCCCCGACCTGGAGCTCCTCCGCCTCACCGCCAGGCCTCTCTGCAGATTGCAAGTTCACCTGCCACTACCGCTGCCGCGCGCTCGTCTGCCTGGACTGTTGCGGGCCCCGGGACCTGGGCTGGGAACCCGCGGTGGAGCGGGACACGAACGTGGTGAGCGCGGGGCCGAGGGCGTATGGGAAGGGCGAGGATGGGCAGGCCACAGTGCAGGCATTCTCGAGGGCTGCCTGGGTGCCGCGCGCAAGGAGCGTTCTAATTGCCGATTTCCCGGCGGCACAGAGAGGCTAATTCTGCGCGGGGGCTGGGAGGGGAGCCTGGATTGCCGGCTCCGCAAGTACTCCACCCGCTGCAAGCGGACCCGGGCCCAGGCTGACCCAGGCTCCGCGCACGCGCACTTCCCGCACCTTCCCGCCCTCGCCTCCGGCCAGAGGCCACTCTTGTGCGCTTGCCCGGACGCTGGCACCCGCCCCCGTTCCCTGTGGTAGGTGGGGTCTGTGAGTGGAGCTCCGGAGCGATGAGGTCATTCCTGGGGGCGAAGCGTGCGTGTCCCCGCCCCGGCGTTCCTGCCCCAATGAGACAAGAGCTAGATCCCGGCGATCTACGTTTCAGTCTTAACGGTTGCGGCGCGGCTCTGGCCCGGGCGCACGCGCACACTGACACGCGTACACGCACGCACGCGACCGGGGCGGTGGTTGGCGGCTACGGACGCGCAGGACTGGGGGACGGGCGGGTACGGCTATGGGCGAGGCGGAGGCGCCTTCTTTCGAAATGACCTGGAGCAGCACGACGAGCAGTGGCTACTGCAGCCAAGAGGACTCGGACTCGGAGCTCGAGCAGTACTTCACCGCGCGAACCTCGCTAGCTCGCAGGCCGCGCCGGGACCAGGTGGGAGCCAGGGGGTGCCGGCGGGCGGGAGGGGAAGCGGTCGCTGGAGCTCCGCCCTCCCCGGTCCGTTGCCGCGTCCTGGGTCGGTGGGCAGCCCCACCCTCCTGGCTACGTGGCTCCCCGCGGGTCCTGGCCGGGGACCTGCCCGCGGAACCGTGCGTAAGACCCCGATTCCACCGCCTAGATGCTGGGTGCCGGGGCCCCCTTGGTTTCTGTCACAGACAGGTTGAACACGGAAAAAGCAGCTGTATGGCTTGTGGTAGACCTGAGCCGGGCATTATCCAGCTATGACTAAAGCCGACCGAGCAGTTTGGACTAGCACCTCGATTTCCGCGTTCGAATGCTCCTGCTCCCTCCTTGGGGAGACTAGGGGAGGATGTGGAGAGGGAAGAGTCCTCGCCAGGAATTGAGAAGTATGTTTAGGAAAACTTGAGAGGCAGAGAGAGATCCTGCTCCTCCATCTGCACTCCTGTATGGAGCCAGCTGAGCCCTCACCTCTTCCCTGTTCTGGCCTGTCACCAGCTGCTGGAATGTGGAAGATTCTGTTCCCTTCCTCTAGGGTGGATCTGGAGAAAGATTTGGGAATAGATAGGAAAGAAGTCTTGTTTTGGACCATAAGCATTCAGGAGCACTTTACCCACAGGAAGGGGGAAAGCTAGATTATAAAATGCCTAAAGAGGTGGAAAAAGAGATCCAGGTTACTAACCCAGGACTGTAAGGTGTCTCGGAACCTCCTAGGTATCCCCATTATCGGAGAACTGTGTGCCAGATGCCATTGGTGTGACCACCAGGCTCAGAGAACCAGGCCTAGGCACCAGGAAAAAGAAACAGGGACTGTGAAGCTCAGTATGCCTGGCAGAAATGGGGCGGAAATCCTTATTTAAGTAAAGAAAGTGGAGTTGTGAGTGATGCTTCAGATAAAATTTTACAAAATTCCTTACAAAATGGGTGGTGCTCAGCACGCCAAAATCTTAGCCCAGAGCTTGGGTGCAAGGGTTGAGTTGAGTGTAGACCCCTGGGCTTGTCTTCATGTCAGTCAGTCCTGAGCCATTTTCCACTGTGGAAAGGTGGGAAAACCACAAGACACTAACCAATTGAAAAGGAGGGCTAGCCACGGAGGTGCACACCTGTAATCCCAGCTACTTGGGAGGGTGAGGCAGAAGGATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGAGTGACAGAGTGAGACTCTGTCTCAAAAATAGAAAAGGAAGCCAAGTACGGTGGCTCACACCTCTAATGCCAATGCTTTGGGAGGCCAAGGCAGGTGGATCATTTGCAATCAGGAATTCGAGGTCAGCCTGGCCAACATGGTGAAACCCTATCTCTACTAAACATACAAAAATTAGCCGGGCATGGTGGTGTGTGACTGTAGTCCCAGCTACTTGGGAGACTGAATCACTTCAACCGGGAGGCAAAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAACCTGGGTGACAGGGTGAGGCTCTGTCTCAAAAAAAAGAAAGAAGGCTGGGCTTGGTGACTCATGCCTGTAATCTCAGCATTTTGGGAGGCCAAGGCAGGCAGATCACTTGAGGCCAAGAGTTCGAGACCTGCCAGGCCAACATAGCAAAACCCCGTCTGTACTGAAAATACAAAAAAATTATCTGGCCATGGTGGTGTGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGTATCACTTGAACCCAGAAGACAGAGGTTGCAGTGAGTCGAGACTGGGCCACTGCATTCCAGCCTGGATGAGAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAGAAAGAATAGGAGGCTGAGAAGTCCCAAGTTATATGTTAAAAAAAAAGAAAAAAACATCAGTTTTAGGCCAGGTGCAGTGGCTCACACCTTTAATCCCAGCACTTTGGAAAGCCGAGGTGGGTGGATCATGAGGTCAGGAGTTCAAGACCAGCCTGGCCAAAATGGTGAAACCCCGTCTCGACTAAAAATACAAAAAATTAGCCAGTTGTGGTGGCAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAAGCAGAGAATTGCTTGAACCCAGGAGGCAGAGATTGCAATGAGCCAAGATCGCACCACTGCACTCCAGCCTGGAAAACAGAGCGAGACTCTGTCTCAAAAAAAAAACCATCAGTTTTTATGGACAGTGGTAGAGTGGAGGGTGGGTCCCTATGGTGCAGAAGGGAAATTCCATGGTCCTGCTGTGCATCCGACTGGGATGGCTGTTGAAATCCTCTTCCAGCAGGCAGCTTTGGAAACAGAAAAAGAAACTCTTCCTCCTTTAGAATCCTGGAAGGGCTGTGCAGTGCCTCTAATCCAAGTCTGTTTTCTGAGTGAAGATAGGGAGGTTCATCACCAGAAGGGAAGGGGCTGGAAATGAGGTCACTGCATCCCAGCCCAGGGCTCCTGGGTCATCCAGGAAGGGAAGAAGGAGCAAGCTTTCTCATTGTTAGGTAGGAGCTCAGAGCCATCACAAGAACAAGTTAGCACCATCCCTGTGCCCTCCCTGTTCTGCAAACAAAATGATCTTCCTTCTTGCCCTGGCACTAGAGTCTGTCTGGCATTTCTCCTGCCCCTAGTACTCCTCCCATCTGGGTACTTCTTCCCGTTGGTGTACTGAACAAACACATCCACTGCTTTATTCACAGCCTCCAGCCCTCATTTTCCAGGGCCCACACCATTTGTTTTTACTAACCCGACAAGGTTGCCCACTGTCCCCAGTAAGGTTTGTACTGGGGTTTTTACTCCAGTGCTCTTCTCCATCCAGGAGACCTTTGGATACTTGGGGAAGAAAATGAGCTTAAATTCCCACCCCTCCCCCTTTACCTTTTTCCTGTAAGGCCCTGGCCTTAGTTCTTAGCCCCACATCCTTGCTGGCTGCAGAATAGCAGCGGGTTCTGGGTAAGGAGCATTCTGCTAAAACGCTCCACCCTGCTCCCTCATCTGTCCTCTCCATTTGTCCCCATCAGATGGTTTAAGTGCTTAAGGGGACTCCAGGGCGGAGTCAGGGAGAACCCTGGCTCTCCTGGGCTAGGCACAAGATCATTCTACAGGAAACCTTGTGGGAATTCTTCTGGGACAAAGTATTGGTCAGCGCTGAGCTTAGCTGTGTCTGTGACACTCGCATTCTAACTAGGGCCTATCTGACGTCAACAGGAAGTAAGGCTGATGCAGTGGGGCCAAGGGAGTCTGGGAGAAGAAAGTCGGTTCAGAGCCCTGGCTGCCCTGTCCCACACTCCACCCTTCCGGCAAGAATCCAGTCCCTAGATGAGGTGGGGAGTGAGTGGTCGAGTTAAAAATCTCTGGGTCGGGTACGATGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGTGAAGGCAGGCGGATCACTTGAGGTCAGGAGTTCAAGACCAACCTGGCCAATGTGGTGAAATCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTTGTTGTGGCACGCGCCTGTAGTCCCAGCTACTCGGGAGTCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAACTTGCAGTGAGCCAAGATCCAGCCACTGCACTACAGCCTGGGCGACAGAGTGAGGCTTCGTCTCAAAAAAAAAAAAAATCTTTGGGCCAAATCTCCAGACAGCACAGGCAGGTGCAGAAACCCACCAGGAAGCTGCCTGTGTACCTCTGGCAGATTGGAGCCTGGCCTAAAGCTGCCTTTTATGCAGCTTGGGTCAAGGTTAAACATCATGTCACAGTGATTTTTCTCACTATGTGTGAGACATGGAGAACTGGCTCCAAGTACTACTCTGTCCACTGGTGGCTGGACTACTGATGTGCACCACTCTCCACTCCTCTCACCCTGCAGTGGGTCATGGCCCCGTGCCGGGGCAGAGGAGAAAAATGGGCTGCCTTCTCCAGGACAAACCCTCACTCCAACTCAACTAGGGTGCTGTGATCAGAATGTGCAATTGAGGTGTGATTTTACTGATTTTTTTTTTTTTTGAGACCGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCGATGGCACGATCTCAGTTCACTGCAACCTCCACCTCCCGAGTTTGAGCAATTCTCCTGCCTCAGCCTCCTAAGTAGCTGGGATTACAGGCATGTGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTAGAATTACAGGCGTGAGCCAACGTGCCCAGCCTGTTTTTGTTTTTTGTGTTTTGAAGCAGGGTCTCACTCAGTTCCCCAGGCTGGAGTGCAGTGACACGATAATAGCTTACTGTAGCTGCAATCTCCCGGGCTCAAACGATCCTCCCACCTCAGCCTCCTGAACAGTTGGGACTACAGGCACACCACCACACCTGGCTAATTTTTTTTTTTCTTTTTTTAGTAGAGATGAGGTCTTGCTATGTTGCCCAAGCTGGTCTCAAACTCCTGAGGATCAAGTGATCCTCCTACCTTAGCCTCCCAAAATGCTGGGATTGCAGATGTGAGCCACCACACCCAGCCTGATTTTACTTTAAATGAGAGTCCCTCTTCAGAGTCCCTCAGCTGTTCCTGGCCCCTGGCCATGTGCCTTCAGTTGCCCCTGCTTCTGTGGTATCCTTAAGGCTACATTCAGTGCTGAGGCCCTAGGCAGGCAGCAGAGAGAAGCCAAATGATTCTGTCTTTCCCTTATCCACCCAGAGCATGCAAAACCAGGAGCAGTGGTGGGTTCAGGGTGGGCACCAGCTATGTATATGTACATCAGGGACAGGGGGCCAAAGGCAGTCAGTTTCCAAAGACTGCCCCAGAGGCCATTTTTCAGAGAAGCCCTGGGTTCCTCAAGGGCCCTGTGTCCATGCTGGCCCATCTTGCAGGACGAGCCTGTGGAGTGGGAGACACCTGACCTTTCTCAAGCTGAGATTGAGCAGAAGATCAAGGAGTACAATGCCCAGATCAACAGCAACCTCTTCATGAGCTTGGTGAGTTGACTGCTCAGGAAGGGGGCGTGGGGAGGAGCAGGTACCCAGCTATGTGCCTGATACTCAGAGGGTCACAACTGAGGTTATCTTGGGTGGGCGCAAGCAGTAATTTGTGCATACCCAGCCTAGCCCCAAGTAGACTGACATCTCACCTGGAACCTATTATCAAGGTTTGGTTTCTCTATTTCTTTAGAACAAGGACGGTTCTTACACAGGCTTCATCAAGGTTCAGCTGAAGCTGGTGCGCCCTGTCTCTGTGCCCTCCAGCAAGAAGCCACCCTCCTTGCAGGATGCCCGGCGGGGCCCAGGACGGGGCACAAGTGTCAGGCGCCGCACTTCCTTTTACCTGCCCAAGGATGCTGTCAAGCACCTGCATGTGCTGTCACGCACAAGGGCACGTGAAGTCATTGAGGCCCTGCTGCGAAAGTTCTTGGTGGTGGATGACCCCCGCAAGTTTGCACTCTTTGAGCGCGCTGAGCGTCACGGCCAAGGTGGGCTTCCCACCCCACCCTGCCCTATGTGAGGGTATATACGCATGCACCTGAGCATGCAGGGGCTGAGCAGCTGGCCCTGTCTCTGATCATTACTTCCCCTTCACAGTGTACTTGCGGAAGCTGTTGGATGATGAGCAGCCCCTGCGGCTGCGGCTCCTGGCAGGGCCCAGTGACAAGGCCCTGAGCTTTGTCCTGAAGGAAAATGACTCTGGGGAGGTGAACGTGAGTACATAGTTCTTAGTTTCTTGGTTGTCACTAGACAGGACTGATGGGCTGTAGCTACAGTAAGGCTTGGAGGAGGAATTGTGCTGGAAGACAAGCCCTGCAAAACAGTTCCAGGAGTGTATAGGCATTGTAACTAAAGCAAAGGCTTCCAGACCACTCATGCCAAAGCCTAGGGTTGTCCCAAGAAGCCAGGAAGAATTGCCTTGGTGCTTTGATCTTTCCTGGTGTGGAAAATCTTCTGGAGATGCAGGAGTCCATCTAATGACATGAGGAGGCCCCCTTCAGACTTTTTACCTGGAAGCTTTCTGGCTCCAAGGTATTAGGCCTGTGGAGTGAAATTAGACTCAGAATATGCCTGACCTGTCCACAGGTAATTGGGGAACATCTGACTTGGTTGTCTCAGTAAGGTGACCGTTTTGTAGGGCCCATCTTCCATACAAACTGCTGTCAGGGATCCTACCAGAGATCATTCAGCCAAGAGCCTGACATCAGAAAGCCCAGTCCTAGCTTGTGTGAACATGAGGTGCTAGTCTTCTCTGGGGAGGGTCTGCTGGCTTGGCCATCCCTTCTGCAGCCTGTACACTCCCCTTTTGCCCCTTGCAGTGGGACGCCTTCAGCATGCCTGAACTACATAACTTCCTACGTATCCTGCAGCGGGAGGAGGAGGAGCACCTCCGCCAGATCCTGCAGAAGTACTCCTATTGCCGCCAGAAGATCCAAGAGGCCCTGCACGCCTGCCCCCTTGGGTGACCTCTTGTACCCCCAGGTGGAAGGCAGACAGCAGGCAGCGCCAAGTGCGTGCCGTGTGAGTGTGACAGGGCCAGTGGGGCCTGTGGAATGAGTGTGCATGGAGGCCCTCCTGTGCTGGGGGAATGAGCCCAGAGAACAGCGAAGTAGCTTGCTCCCTGTGTCCACCTGTGGGTGTAGCCAGGTATGGCTCTGCACCCCTCTGCCCTCATTACTGGGCCTTAGTGGGCCAGGGCTGCCCTGAGAAGCTGCTCCAGGCCTGCAGCAGGAGTGGTGCAGACAGAAGTCTCCTCAATTTTTGTCTCAGAAGTGAAAATCTTGGAGACCCTGCAAACAGAACAGGGTCATGTTTGCAGGGGTGACGGCCCTCATCTATGAGGAAAGGTTTTGGATCTTGAATGTGGTCTCAGGATATCCTTATCAGAGCTAAGGGTGGGTGCTCAGAATAAGGCAGGCATTGAGGAAGAGTCTTGGTTTCTCTCTACAGTGCCAACTCCTCACACACCCTGAGGTCAGGGAGTGCTGGCTCACAGTACAGCATGTGCCTTAATGCTTCATATGAGGAGGATGTCCCTGGGCCAGGGTCTGTGTGAATGTGGGCACTGGCCCAGGTTCATACCTTATTTGCTAATCAAAGCCAGGGTCTCTCCCTCAGGTGTTTTTTATGAAGTGCGTGAATGTATGTAATGTGTGGTGGCCTCAGCTGAATGCCTCCTGTGGGGAAAGGGGTTGGGGTGACAGTCATCATCAGGGCCTGGGGCCTGAGAGAATTGGCTCAATAAAGATTTCAAGATCCTCCTGC

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