Details for gene: THBS1


The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]


Symbol
THBS1
Name
thrombospondin 1
Entrez ID
7057
Ensembl ID
ENSG00000137801    (more details)
KEGG ID
hsa:7057    (more details)
OMIM ID
188060
Uniprot ID
P07996  
GO ID
hsa:7057    (more details)
Chromosome
15
Strand
1
Start
39581079
End
39599466
miRNA Interactions
hsa-miR-29b-3p (RPM: 118.8178) / hsa-miR-20a-5p (RPM: 55.9816) / hsa-miR-141-3p (RPM: 2843.5066) / hsa-miR-195-5p (RPM: 125.6474) / hsa-miR-132-3p (RPM: 82.2598) / hsa-miR-29c-3p (RPM: 661.3514) / hsa-miR-30a-5p (RPM: 15590.711) / hsa-miR-29a-3p (RPM: 1246.9046) / hsa-miR-4739 (RPM: 0.01) / hsa-miR-124-3p (RPM: 4110.4386) / hsa-miR-34a-5p (RPM: 81.3502) / hsa-miR-16-5p (RPM: 2473.4704) / hsa-miR-200a-3p (RPM: 157.5826) / hsa-miR-27b-3p (RPM: 22876.2392) / hsa-miR-455-5p (RPM: 19.0882) / hsa-miR-182-5p (RPM: 77446.6216) / hsa-miR-101-3p (RPM: 3335.0564) / hsa-miR-205-5p (RPM: 5027.3352) / hsa-miR-3163 (RPM: 0.012) / hsa-miR-135b-5p (RPM: 25.9152) / hsa-miR-147a (RPM: 0.0014) / hsa-miR-922 (RPM: 0.0014) / hsa-miR-942-5p (RPM: 2.297) / hsa-miR-3065-5p (RPM: 5.6206) / hsa-miR-27a-3p (RPM: 980.3062) / hsa-miR-377-3p (RPM: 4.0398) / hsa-miR-335-3p (RPM: 837.9252) / hsa-miR-379-3p (RPM: 2.3026) / hsa-miR-450b-5p (RPM: 4.6184) / hsa-miR-493-5p (RPM: 18.0762) / hsa-miR-548c-3p (RPM: 0.0894) / hsa-miR-135a-5p (RPM: 34.8504) / hsa-miR-19b-3p (RPM: 197.0578) / hsa-miR-19a-3p (RPM: 25.4064) / hsa-miR-380-3p (RPM: 1.6668) / hsa-miR-758-3p (RPM: 5.044) / hsa-miR-411-3p (RPM: 2.5412) / hsa-miR-125b-5p (RPM: 10044.3546) / hsa-miR-374a-5p (RPM: 52.6724) / hsa-miR-107 (RPM: 234.4574) / hsa-miR-92a-3p (RPM: 16961.15) / hsa-miR-138-5p (RPM: 67.2828) / hsa-miR-513a-5p (RPM: 0.3656) / hsa-miR-503-5p (RPM: 0.0972) / hsa-miR-495-3p (RPM: 8.062) / hsa-miR-103a-3p (RPM: 2034.8158) / hsa-miR-5006-3p (RPM: 0.4468) / hsa-miR-96-5p (RPM: 1417.2834) / hsa-miR-148a-3p (RPM: 10339.6222) / hsa-let-7b-5p (RPM: 3396.2052) / hsa-miR-579-3p (RPM: 0.0084) / hsa-let-7f-5p (RPM: 17066.6836) / hsa-miR-129-2-3p (RPM: 79.8688) / hsa-let-7c-5p (RPM: 4028.6728) / hsa-miR-125a-5p (RPM: 11539.4616) / hsa-miR-148b-3p (RPM: 970.7614) / hsa-miR-3612 (RPM: 0.0154) / hsa-miR-125b-2-3p (RPM: 492.7724) / hsa-miR-199b-5p (RPM: 234.7942) / hsa-miR-766-5p (RPM: 0.1124) / hsa-miR-365a-3p (RPM: 22.318) / hsa-let-7i-5p (RPM: 2025.2084) / hsa-miR-186-5p (RPM: 1645.2832) / hsa-miR-98-5p (RPM: 1660.0964) / hsa-let-7e-5p (RPM: 3790.2074) / hsa-let-7g-5p (RPM: 3559.4376) / hsa-miR-221-3p (RPM: 758.7978) / hsa-miR-30e-3p (RPM: 538.304) / hsa-miR-30a-3p (RPM: 889.1386) / hsa-let-7a-5p (RPM: 32160.4734) / hsa-miR-449a (RPM: 1.3118) / hsa-miR-1827 (RPM: 0.03) / hsa-miR-484 (RPM: 434.5276) / hsa-miR-4500 (RPM: 0.0022) / hsa-miR-7-1-3p (RPM: 13.9534) / hsa-miR-3121-3p (RPM: 0.036) / hsa-miR-3149 (RPM: 0.0328) / hsa-miR-4450 (RPM: 0.0562) / hsa-miR-7-2-3p (RPM: 0.451) / hsa-let-7b-3p (RPM: 92.0818) / hsa-miR-455-3p (RPM: 82.7264) / hsa-miR-7-5p (RPM: 19.3682) / hsa-miR-664a-3p (RPM: 65.4214) / hsa-let-7a-3p (RPM: 33.7298) / hsa-miR-509-5p (RPM: 1.1668) / hsa-miR-194-5p (RPM: 48.9448) / hsa-miR-127-5p (RPM: 9.9124) / hsa-miR-374b-5p (RPM: 72.7188) / hsa-miR-410-3p (RPM: 194.4724) / hsa-miR-130a-5p (RPM: 1.1956) / hsa-miR-214-3p (RPM: 21.2784) / hsa-miR-509-3-5p (RPM: 0.912) / hsa-miR-494-3p (RPM: 1.1806) / hsa-miR-5680 (RPM: 0.2512) / hsa-miR-136-5p (RPM: 38.7962) / hsa-miR-143-3p (RPM: 93089.5152) / hsa-miR-214-5p (RPM: 5.1378) / hsa-miR-199a-5p (RPM: 174.3046) / hsa-miR-21-5p (RPM: 5494.851) / hsa-miR-127-3p (RPM: 3339.395) / hsa-miR-203a-3p (RPM: 1346.5646) / hsa-let-7d-5p (RPM: 1078.3154) / hsa-miR-2467-3p (RPM: 0.0206) / hsa-miR-181d-5p (RPM: 168.2728) / hsa-miR-22-3p (RPM: 26348.475) / hsa-miR-145-5p (RPM: 548.8656) / hsa-miR-181b-5p (RPM: 3069.8278) / hsa-miR-181a-5p (RPM: 52364.6344) / hsa-miR-18a-5p (RPM: 3.6074) / hsa-miR-92a-1-5p (RPM: 8.113) / hsa-miR-193a-3p (RPM: 13.6064) / hsa-miR-449b-5p (RPM: 1.2108) / hsa-miR-1-3p (RPM: 26.3428) / hsa-miR-193b-3p (RPM: 184.968) / hsa-miR-1343-3p (RPM: 3.6608) / hsa-miR-34c-5p (RPM: 46.7356) / hsa-miR-320b (RPM: 35.0146) / hsa-miR-320c (RPM: 5.4174) / hsa-miR-4637 (RPM: 0.0012) / hsa-miR-4458 (RPM: 0.0998) / hsa-miR-199b-3p (RPM: 360.8262) / hsa-miR-671-5p (RPM: 10.1036) / hsa-miR-23b-3p (RPM: 2125.0486) / hsa-miR-199a-3p (RPM: 731.3038) / hsa-miR-92a-2-5p (RPM: 0.5724) / hsa-miR-5003-5p (RPM: 0.0012) / hsa-miR-628-5p (RPM: 28.0514) / hsa-miR-23a-3p (RPM: 613.2568) / hsa-miR-376a-5p (RPM: 4.9822) / hsa-miR-485-3p (RPM: 10.0736) / hsa-let-7a-2-3p (RPM: 0.3976) / hsa-miR-23c (RPM: 1.4294) / hsa-miR-22-5p (RPM: 21.6092) / hsa-miR-224-5p (RPM: 33.3102) / hsa-miR-222-3p (RPM: 1699.0194) / hsa-miR-491-5p (RPM: 1.4644) / hsa-miR-769-5p (RPM: 505.4938) / hsa-miR-505-3p (RPM: 14.5424) / hsa-miR-665 (RPM: 0.445) / hsa-miR-17-3p (RPM: 13.6088) / hsa-miR-376c-3p (RPM: 10.6544) / hsa-miR-146b-5p (RPM: 934.8654) / hsa-miR-20a-3p (RPM: 0.8156) / hsa-miR-342-3p (RPM: 685.7862) / hsa-miR-675-3p (RPM: 2.5462) / hsa-miR-146a-5p (RPM: 774.8698) / hsa-miR-155-5p (RPM: 106.9134) / hsa-miR-34b-5p (RPM: 1.8778) / hsa-miR-425-5p (RPM: 187.631) / hsa-miR-532-3p (RPM: 21.9476) / hsa-miR-409-3p (RPM: 127.9804) / hsa-miR-675-5p (RPM: 0.6068) / hsa-miR-17-5p (RPM: 83.6404) / hsa-miR-2682-5p (RPM: 3.1332) / hsa-miR-193b-5p (RPM: 3.2336) / hsa-miR-181a-2-3p (RPM: 1451.5764) / hsa-miR-29a-5p (RPM: 3.125) / hsa-miR-211-3p (RPM: 66.2628) / hsa-miR-297 (RPM: 0.0048) / hsa-miR-377-5p (RPM: 8.4706) / hsa-miR-34a-3p (RPM: 0.9902) / hsa-miR-4302 (RPM: 0.0012) / hsa-miR-590-5p (RPM: 0.1536) / hsa-miR-140-5p (RPM: 21.3322) / hsa-miR-125a-3p (RPM: 24.5112) / hsa-miR-1234-3p (RPM: 0.3324) / hsa-miR-550a-3p (RPM: 2.5866) / hsa-miR-15b-3p (RPM: 6.693) / hsa-miR-3609 (RPM: 6.639) / hsa-miR-126-3p (RPM: 494.5936) / hsa-miR-1909-5p (RPM: 0.0272) / hsa-miR-100-5p (RPM: 3365.0918) / hsa-miR-1307-3p (RPM: 130.8454) / hsa-miR-941 (RPM: 399.631) / hsa-miR-487b-3p (RPM: 27.5062) / hsa-miR-522-5p (RPM: 0.0018) / hsa-miR-99a-5p (RPM: 1181.6944) / hsa-miR-210-3p (RPM: 361.0562) / hsa-miR-425-3p (RPM: 26.9044) / hsa-miR-191-5p (RPM: 12993.8088) / hsa-miR-99b-5p (RPM: 14318.7458) / hsa-miR-151a-3p (RPM: 2381.562) / hsa-miR-190a-3p (RPM: 0.756) / hsa-miR-6825-5p (RPM: 0.261) / hsa-miR-1252-3p (RPM: 0.0174) / hsa-miR-6733-3p (RPM: 0.0034) / hsa-miR-6766-5p (RPM: 0.0116) / hsa-miR-6516-5p (RPM: 0.859) / hsa-miR-6754-5p (RPM: 0.0514) / hsa-miR-6857-5p (RPM: 0.0034) / hsa-miR-1910-3p (RPM: 0.3614) / hsa-miR-6511a-5p (RPM: 0.4256) / hsa-miR-6777-5p (RPM: 0.557) / hsa-miR-6889-5p (RPM: 0.041) / hsa-miR-4655-5p (RPM: 0.0316) /
Involved Diseases
diabetic retinopathy /
Involved Pathways
Rap1 signaling pathway / PI3K-Akt signaling pathway / MicroRNAs in cancer / p53 signaling pathway / Focal adhesion / ECM-receptor interaction / TGF-beta signaling pathway / Proteoglycans in cancer / Bladder cancer / Malaria / Phagosome / Generic Transcription Pathway / RNA Polymerase II Transcription / Gene expression (Transcription) / Disease / Metabolism of proteins / Post-translational protein modification / Hemostasis / Extracellular matrix organization / Signal Transduction / Signaling by PDGF / Integrin cell surface interactions / Non-integrin membrane-ECM interactions / Signaling by Receptor Tyrosine Kinases / Diseases of glycosylation / Diseases of metabolism / Platelet degranulation / Platelet activation, signaling and aggregation / Response to elevated platelet cytosolic Ca2+ / Syndecan interactions / Diseases associated with O-glycosylation of proteins / Defective B3GALTL causes Peters-plus syndrome (PpS) / O-linked glycosylation / O-glycosylation of TSR domain-containing proteins / Transcriptional regulation by RUNX1 / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function /
Sequence
AGCCGCTGCGCCCGAGCTGGCCTGCGAGTTCAGGGCTCCTGTCGCTCTCCAGGAGCAACCTCTACTCCGGACGCACAGGCATTCCCCGCGCCCCTCCAGCCCTCGCCGCCCTCGCCACCGCTCCCGGCCGCCGCGCTCCGGTACACACAGGTAAGTCGCCCCCGGCGGCCGCCGAGGACCAAAGCTGCCCGGGACATCCACCTGGAGCGCTGAGGCTTCAGTCCCTCTGGTGGACCCCGGAACCTACACTCTCCCCGCTCGCCTACCCCAGCCCGCTCCTCTCAGCCGCTGGAGGACTCTTCAGGGCAAGGCTCCAGAGCCATCCTCTCCAGCCTTGAGGTTCACAAACCAACTCATCAGGACACCCCAAGATTTCCTTACTCTCTGAAGTCCTCCTTAAGCCTTTGTATCAGCACTCCAGGGAAGAGTCTGTACTTCCCCTGCCCTCCCTGCAACCCCAAACTACAGTTCCTGATCTTGCTCACCTTCGACTTCCCAAAAGCCCCCAAATTGTTGGTCTTGCGCCCCCCACACTTTAAAACCAGCATCTCTTTCCTCCACCTCTCTCTCTCTCTCTCTCTCTCTCTCTCATGCTCTCTGGAAAGTAATCCTGTTGTCCTTCATTTCAGCAAACGCGGGGTCAAAGAGGGATGGTCCCGGCCCTGTCCCCATGCCCAGCCCCGTTTCTGCGCACCGTCCCTCCCTGCCTAGCTGATCTCTGACCCTCGGCTCTTGTGCTTCCTGCTACAGGATCCCTGCTGGGCACCAACAGCTCCACCATGGGGCTGGCCTGGGGACTAGGCGTCCTGTTCCTGATGCATGTGTGTGGCACCAACCGCATTCCAGGTGAGTTTGTGTGGCACCTTTAGGGGAAGGAGGGACAAGGAAGAGGTGCTGGCTATCCCAGGTGTGCCCCCTCACGTGCTGTCCTCTCCCTCTTGAGCCTGACTGGACATCAGGACGCAGCTTCACTCTGATCCTGGTATTTATTCACCTCTTTCAGTGGTTGCCAGGAGTTTTCACCCCAACCCTTTGTCTCCACCCCTAAGGACTCAGCCCCCTACTGCTGGTCCCAGCCTAGAAAGCTCACTTTGTGTTCTCTCCTGTCTAACAGAGTCTGGCGGAGACAACAGCGTGTTTGACATCTTTGAACTCACCGGGGCCGCCCGCAAGGGGTCTGGGCGCCGACTGGTGAAGGGCCCCGACCCTTCCAGCCCAGCTTTCCGCATCGAGGATGCCAACCTGATCCCCCCTGTGCCTGATGACAAGTTCCAAGACCTGGTGGATGCTGTGCGGGCAGAAAAGGGTTTCCTCCTTCTGGCATCCCTGAGGCAGATGAAGAAGACCCGGGGCACGCTGCTGGCCCTGGAGCGGAAAGACCACTCTGGCCAGGTCTTCAGCGTGGTGTCCAATGGCAAGGCGGGCACCCTGGACCTCAGCCTGACCGTCCAAGGAAAGCAGCACGTGGTGTCTGTGGAAGAAGCTCTCCTGGCAACCGGCCAGTGGAAGAGCATCACCCTGTTTGTGCAGGAAGACAGGGCCCAGCTGTACATCGACTGTGAAAAGATGGAGAATGCTGAGTTGGACGTCCCCATCCAAAGCGTCTTCACCAGAGACCTGGCCAGCATCGCCAGACTCCGCATCGCAAAGGGGGGCGTCAATGACAATTTCCAGGTGAGGCTTCTTCTCTGAGCCCTGCTCCGTGGGATCATCTGCTAGACAGGTGACCTGCCAGGAGGGCTACAGGAAATCCTGTCTGTAAACTAACGCAGCAGTTCTCAGATTTTAGGCAGCATGAGCATCACCTGGAGGGCTTGTGAAAGCTCACCCTGCTGCACCCCAGCCCCAGAGTCTGGGATTCTGTAAAACTGCAACTCTAACAAGTACCAGGTGATGCTGATGCCGGTGGTCTGGGAAGCACACTTTGAAAACTACTCAAGGAAACAAGAAATGGTTTTCCTTTAGCAGTCAGCCTGTTCAAGCCTTAGATACTCCTTAGGCTCTTAAGAAAAGAGCTTATTTCAAATGCATTCCCCCAATTTTAATCTTGTTTGAAATGGATACTTTCTATGGGCAGAATCAGTACCACTTTGCTATTGGATTCCTCATGGGGATGCAGCTGGTCTCACATAAAAGGTTAAAATAGCAGTTAGTTGTTGCTGTTACAGCTTCATCTGTGCCTTAACTTCTAGATCTTTGCAACGGTGGCTTTGAACTCCCACATTTAACTCTTTGACACTGGAAAGTGTCATTATATCCTCTAGGCTTAGGATCAGATTCCATTTCCTGTGTACCCAAGTAGGCTGATAACTGAATTCTTTGTAAAATACTCAAGACTTGGCAGAAGTCACAATTAAGATTTTGAAGTTGTTTGGCGATTAATGTTGCTGTGTTATTTTGACATAGTGATCTTAAGACAGCTCTTTGAAGCTTTTAGAACATCTATTGTATGCTTTTCCTAGCATACAGACAGTCTCCCCCAACCCCATCCCCACCCCGCTCTGCATTCTACAAGTAATGTGTGTCCTCTGCCCACAGGGGGTGCTGCAGAATGTGAGGTTTGTCTTTGGAACCACACCAGAAGACATCCTCAGGAACAAAGGCTGCTCCAGCTGTGAGTACCCCTCTATTTTTAGGGCACATAGGGAATCAGGGGGAATTCCACCAAAAACAAACTGAGGAATTTAGCAATAGTGGTTATACATAAATTACCCCCAGTGAGATCATCAAGAGGCATACAGAAGTGACTCCAAGGGGTATTATACACACACACGTATACACACGTGCGCATACACGCAACCCCTCTACCTGCATCCTTCACACCAAATGAAACGTCTTCTACCACTAAGAACTCAAGAGGCTGGTTGGTAAGAGTATCTATTTGAAGTTTTCATTTTGTTTCTTGCCAGCTACCAGTGTCCTCCTCACCCTTGACAACAACGTGGTGAATGGTTCCAGCCCTGCCATCCGCACTAACTACATTGGCCACAAGACAAAGGACTTGCAAGCCATCTGCGGCATCTCCTGTGATGAGCTGTCCAGCATGGTCCTGGAACTCAGGGGCCTGCGCACCATTGTGACCACGCTGCAGGACAGCATCCGCAAAGTGGTCAGTGGCCTCTGCACCCAGCCCGTTAGCATGAACCCTGGAAGGTTTATCGCAGATGGTCCCAAATGACTGAAAATGCGGGGGGACACTAATGATATTCTCTCCCATTTAGACTGAAGAGAACAAAGAGTTGGCCAATGAGCTGAGGCGGCCTCCCCTATGCTATCACAACGGAGTTCAGTACAGAAATAACGAGGAATGGACTGTTGATAGCTGCACTGAGTGTCACTGTCAGGTAAGGGACCTTCACCAGCCAGAATAAGAATCGACGGCTTTTGTTTGAACCTACATCTTTGGGGAAATACCCTAATCGCCACAGAGATTCTTTTTATGTTCCATGGCCTGATAACAAAGTGTTTTTTTTTTCTTTAAGATGCAATTATGGCATCTATAAGTTCTTCTTTAAACTCTCAGATGGTTTATCAAAGTATTAATTATACCCCAGGCTAAGTATCTAAGAGAATGAATCTACTAAGACATCTGAATAATTTACCTACCTTAGTTCAAAGACTAAGTGTTGAATGTCAGGTAAATAAAACCTGGTTGGAACATTCATTTTTTTTTCCCAACCCTGATTTATATTCAGCTTTGGCATAGGTTCTTTTAGTACAGTAGCAATTGTTTTTCAAATCACTTAGTCTGACACTGTTAGGATGTTACTGTCTGCTTTGCTCAGATGGCACTGCCAGGTGTGTGATTCACTCTAGCATCCCCGCATGCCAGTGGCCAGTGAGTTTGGAGGTTCACCTGGCTTATCTATTAATAGCAAAGTATTTGAATTTGCTTAAATACAAATCACAGATGACTGGCTGTGGGAACCAACTTCATTAAATTCCCTTTCTTTTCCAATATAAAGACAGATCACAGATCTATAGATGAGGAAAAAGTGCTTATAGATCTTCCTTCCTCCCCCCAAACACATAATATAAAAATGTAAAAGTCCTGGCTGAATTTTCTGAGTTTGATTTCAGACATAGATTTGACCCATGATGTTTGTTGGTTCCTCTGCTATAAATTCTTTGTACTGTAACTTCCACCCTTGACTAAGTAGCAATTAAAAAGAACTTTCCAAGGAATGGAGTGACACGTAAACTAGCACTAGAACTGTCTCTACGATAGTGGTGGCTGCAAATATGACAGAGACAGATCTATGAAAATCATTCCACTAGAGCATTGACAGCCCTGACCATGTTTTGGCTTGTAAAGGAAATGTTACAGGATGTAGACTTCTGTATGCAACATGCTCAGCAGCCTGTTCCCCTCTCACTCTCTTGCCCTGCAGAACTCAGTTACCATCTGCAAAAAGGTGTCCTGCCCCATCATGCCCTGCTCCAATGCCACAGTTCCTGATGGAGAATGCTGTCCTCGCTGTTGGCGTAAGTTTCTCAAATGGCATAGCTATTCTTCAGTGACTAGGTCAGTTCTACATACATCCTAGACAGCCGAGCACAACACTGGAACCCCACCCCCATCTCCATCATGCTTCCATTCAGTTTCTTGCTGCAGCAGCTGGTTAACTGACAGCTTATCTGCTGTACAGAGCCAAAACTCCATTATGAGTACATCGTAATTACCCATCTGGATTGCAGTAATGGCAGTGAAGATCTTGGTATAGCTCATTAATTCTGATTTTTTGCTTTGAGGAAAAGAGATGAAGACGTGGCAGCAACAGCTCTAAGTTGACTGCTTTTAGAATTTGACCTTAGTGGCACAGAGTTAAGAAAAATCTGCTCACCAGAGATATTGACAGGCTTACTGTGTAAGCATTGGCCTGATCGGGCCTGGAAGTTTTGCCCCTTTCATCTGTAGGGATAAGAGGGCCTAAGAGAATAGCAGCAATCTGAGCTCTAGAGCACCAAAAGAAATAAGGCACGATATCGTTCCATGGCACGTTATCCCTGGCTTTTGTTACCAGTAAAATGAATGACTTTGCTGAGACAATACTTAGTGTAGCAGGTACAAGTTATAAAAGTGATTCATTACAACTAAGATAAGGAAGAAAACAGGAAAACAGCACTTGCCCTTCACACACACAGAAACACACATGCACACACACACAAACACACCCTTGTCACAGCTCAGAATAACCAATTCCATCCAGGGATCATATTAGCGATATTGGCACTGTAATGGTCGTTTTTACATTTATTTTCTGTTCCGCATTCACTTAACATGTGCGTTAAAAGGAACAAAGCTAGCTGGAGGTAGCAAAGTTTTGAACTTGAATCAGGGATTGCTAAGAAAACTTACAACTAATGACCACAGAAAGTAAGTTCTTTGTCTTCTGTCTGATACAGCTAGATGTGATTGTAGCCGTGGTGCCTGGGCAGATGGTAAACAAACATGCTGTCCTCTTATGACAATATGTGCAGAGAAGGCCCCAAACGCTGGGGTGAGAGGAACAACAAACTGACTAACTCACGGCCGAGTTGGAGCCAGAACCAACAACAGCTCGGCTGCCTTCACACTCATCTGTCAAACACATGGTGTATGGCTCCCCTGACAGAAATGACTCCTATAAGCTTCCTCATACTCGCGCATTCTTGGAAGTCTGAGACTGGAAATGCCTACCCAGATATGTTAAGTCAGTAAAGGAAAACTCATTTGCAATGCTGAGAGGAGAAAGAAAATCAATGAATAGGAGAGCATACACTGTGGGAAGGCTCAGCTGTACTGAGCCAGGCAAAGCATCCGATTACCCCACTGCTGTACACATCATGACCTGGGATAAACCCCTGGGCCGTTGGCCTAAGAAATATGTTGCTTTTCATCCTGTATAACTGCAACTTTGTGCCGGCTCATATTATGTTCTAGAGAGCTCATGTACACCATGGTGACCATAGTTAATAATACTGGATTGTATGCTTAAAATTTGCTAAGAGAGTAGATCTTAAGTCATCACCAAAAAAAGTAACTGTAAGATGATGGAGATGTGTTAATTAGCTTGACGGTGGTAATCACAATATATGTGTATATCAAAACATCACATTATACACCTTAAATGTATATAATATTTGTCAATTATACCTCAGTAAAGCCAAAAAGAAATAAATATATTGCTTTTCACCCTCTGGCAAGTGGAGGGCCCTGAACAGAGCCCTCTAAAGAACAGCTTGTCCTAATCATCACGTACCTGATGAACCTCTGTTTCCCCTGCAGCCAGCGACTCTGCGGACGATGGCTGGTCTCCATGGTCCGAGTGGACCTCCTGTTCTACGAGCTGTGGCAATGGAATTCAGCAGCGCGGCCGCTCCTGCGATAGCCTCAACAACCGATGTGAGGGCTCCTCGGTCCAGACACGGACCTGCCACATTCAGGAGTGTGACAAGAGATGTAAGCATCTTAGCCTCTCAGGGACGTGGAGAACTGACCTGTCCTTGTTGTCGTCACCAAGGGCAGCTCCACAGCATGTATATTAAGAACACGGGTTCTAGGATCTCTGGATCCCAATCCCACTGCTTAGCTGTGCACCCTTGAACACAACTTACCCTCTCTGAGGCTCTTTCCTCATTTGCAACTTGGAGATAATAATAGTTCTTGATAAGTTTATCTTGAGCATTTTATTTAGATACTGCATGTAAAGCAGTTAGCACTGAGTTTTGGTTTATGGTAAGCACCCTGTAAATGTTAGGATATTAACAGCAACCCATAAAAACAGCGAACTTATCCGTTCTCTGGTAGAAAACATTCCATGTTGACATTTGGGCATGTGGCCAGGAGCCAATTTCTACCGTACACTGGGTTTAGTTGCCATTGACCATTTCCTGGAAATACTTCTGCGTGCTCCTGATGGGAGCCTCTATTTGGCTGTCTCTAAGCCAAAACCATTTGTGACCATCAACTCTGTACTTTAGTTAAACAGGATGGTGGCTGGAGCCACTGGTCCCCGTGGTCATCTTGTTCTGTGACATGTGGTGATGGTGTGATCACAAGGATCCGGCTCTGCAACTCTCCCAGCCCCCAGATGAACGGGAAACCCTGTGAAGGCGAAGCGCGGGAGACCAAAGCCTGCAAGAAAGACGCCTGCCCCAGTAAGTGTGAGGTCCGCTGCAAGGGTGAGCATGGGCAGCAGCTCTGCCCAGCTGGTTGCCTGGCATCTGCAGCCTGCAGTTCAGTGGGTCATAGAGCAGGAAGGTTACCTACTAGAGAAACAAACAGAAGCAAAGTCCTGCAGGCTCAGCAACTTCTTTTAATGAAAAACAAACTCACCCTCTTCCCCAGCATTCTTTCCATGTGTCAGAGAAGCAGAGGTTTCTTGAACGGGCTTAGGAGAGTCTATGACAAGGGAGGGATTTGAAAGTTGATCTTAATTGTTGCCTGTGGTTCATCTTCTTACAGTCAATGGAGGCTGGGGTCCTTGGTCACCATGGGACATCTGTTCTGTCACCTGTGGAGGAGGGGTACAGAAACGTAGTCGTCTCTGCAACAACCCCACACCCCAGTTTGGAGGCAAGGACTGCGTTGGTGATGTAACAGAAAACCAGATCTGCAACAAGCAGGACTGTCCAATTGGTGAGCCACGCAGCCCAGGATGAAACGACCCAGGAGCTTTGCTCTTTTACTGAATGCTGCAGTCAGCATTCGAGGAGATTCCAGCTTGGTTAGTCCTGAGCGATTTGATTGCTCTAAGATGCAGGTGGACAACATAATCCCAACAAGTTATCGGTTCCCTATACCCTATAATATCTTACACTGTGTTAAGTGCCCAGCATGGCAGTATGGCAGCTTAGACCAACCATTTACTGTGACTGTCTCTCTCTCCTTGTCTCAGATGGATGCCTGTCCAATCCCTGCTTTGCCGGCGTGAAGTGTACTAGCTACCCTGATGGCAGCTGGAAATGTGGTGCTTGTCCCCCTGGTTACAGTGGAAATGGCATCCAGTGCACAGATGTTGATGAGGTGAGGAACTGATGGGGCTCCGAGTTTCTGGATCTAGGAAAGCAGCTAACCTGTGCAGTCGCTTCCTTATGGCAGTGACTTCTAAACATGATGCACGCTCTTATTTCCTCCATAGTGCAAAGAAGTGCCTGATGCCTGCTTCAACCACAATGGAGAGCACCGGTGTGAGAACACGGACCCCGGCTACAACTGCCTGCCCTGCCCCCCACGCTTCACCGGCTCACAGCCCTTCGGCCAGGGTGTCGAACATGCCACGGCCAACAAACAGGTACAGTCAACTAGACGAGTAAACCAGAGGACAGGAGAGCTGTCCTTGACCAAAATAACTGGGAGCGGGAGGAATGTAATTTCATACCCTTCACCAAAAAAAAAAGGGCGAGGAGATGAATGTACGGTCTAGTTTTAGAAACGTGATTAGAAAATCCATGGTAAATCCTGCAGGGGAAAAACAGTCTTCCATATTTAAAAATGCTGCTCTGGAATAAGTTGTGAGCAGATGGACTTGTAAACGCCTAGGTGCTGAGCAAATTCAAGAAAAATAAACATAAAGCAAAGTTTGCTTATAGCCTCAGGGAGAATGGGGAGGGACAGAGGTAACCCACACTCTTCCAAATGGAGCCTCTGTCTACTCAGAGATGACAGGGATCTGGATTCTTGTTTCCATGATATCTGAGGATTCTCAAAAGCTCTGTGTAACAGCAGCATGGTGTACCCTCAGGTGTGCAAGCCCCGTAACCCCTGCACGGATGGGACCCACGACTGCAACAAGAACGCCAAGTGCAACTACCTGGGCCACTATAGCGACCCCATGTACCGCTGCGAGTGCAAGCCTGGCTACGCTGGCAATGGCATCATCTGCGGGGAGGACACAGACCTGGATGGCTGGCCCAATGAGAACCTGGTGTGCGTGGCCAATGCGACTTACCACTGCAAAAAGGTAGAGCCAGGTCCTTTGTGTGCCTCCAGAAAGAGGGCCCATCACCTTATCAAAACACAGGCTAAGGAATTTTAAATACTTAAAGTTTGGACATGAAACTGAAAGATTAAATCTCCCAAAGGGAGAGGGGCACTAATTCCTATTAAAATTAAATCACTTGGTGCCAAAAACATGAACAGGGCTAGCTCTTTTTGGGCAACTGTGTTCCATAGTCAACTCTTCTGTCCAAAAAAAAGTTCAGTACTCTATCCAAATACCAGCAAAGCATGACTTGTGTTCACAACATCTATAAAGCCTAGAGCATTTACACAAATTCTGTATGTATATCCCCCAAGAAAAGTTTTATTTTCTTGTCTTCCCATAAAAAAAATATGCTGTTACTGAGCCAAATTCTGTTCTTTTTCTATTTGGAATTCCAGGTACACTCCCTCGTGCATGAGCTCAGCATGAGGAAGGCAACTGAAGCAGTGATATATATCTTCTCTTTCCTAGGATAATTGCCCCAACCTTCCCAACTCAGGGCAGGAAGACTATGACAAGGATGGAATTGGTGATGCCTGTGATGATGACGATGACAATGATAAAATTCCAGATGACAGGGTAAAAACAGTTTTCTATCCCTTTTTCATCTTTTCAGTTCAGCAACAGCCTGAAACACTTTGGGATTCAAGGAAATTACATGGCTATAGCAAAAAATATACCAAATCAATACACAGGATAATTAGAAATTATTCATTGTGTTCCAGTAGTTTAAGGATGTAGATGTTGCCAAGAGAATTTTTAAATGAGGGTTTTGTTTTTCATCAGAACTGTTTTTCTCTGTACTTGAGAAATTATAATGCATAAACAAATGCCACTTTGTTCCCTAGATTCATTTCAAATGTCACATCGAAATTACAGTAAAATTGACTTTGGGCACACTATGAACTGAGATGATGGGATTATATTCTACATCTCACTAACTTCTAACCCACAGGGATCCATTTTTTTAACTATGTCCTTTTAACTTTTGTAGTGATCGTTTTACACTGAGTGATCAATTAGCCTATCCACTAGGTAGAAAGTATTGCTGATTTTCACAGTTTTAGACATATTATGCACATGGTTTGAGGCTTGAGCTGTTTTCAAGGACAACATTGTTAAGTGCTCCATTTCTTCTCTTTGCAGGACAACTGTCCATTCCATTACAACCCAGCTCAGTATGACTATGACAGAGATGATGTGGGAGACCGCTGTGACAACTGTCCCTACAACCACAACCCAGATCAGGCAGACACAGACAACAATGGGGAAGGAGACGCCTGTGCTGCAGACATTGATGGAGACGGTAAGGTGCTGCCTGATCAGAGGGCCCGCGGGAGACAGGGACATGCACAGCTTTCCAAACGTACTTCTGTCTAGTCCTGGCTATTAGTATGCACTTTGGTGGAAACATCCAAGGCTGGAGAGCCCAGCTCTTATTTGTCCCTTGTTCTCTTCAGGTATCCTCAATGAACGGGACAACTGCCAGTACGTCTACAATGTGGACCAGAGAGACACTGATATGGATGGGGTTGGAGATCAGTGTGACAATTGCCCCTTGGAACACAATCCGGATCAGGTAGGTGGATGGACTCCTTTCAGAGTCTTTCAGTAAACTGTTGGAATATCCCTTTCATGGCCTTTGAAAAATGAGCTTAACAAAGTTCAAACACTTTCATTACTGTGGCTCCCTGGCTTCTCATAGCCAACTGGAATACGTTCATGTAAATAATTTGCCTGATGTGAGCTCCTTGCACAGAGTCTCACAGATCTTTAGCATGAAGATCTGGTAACTTCAGTCTTACCTTCTGTAAGAAGGGCTACTGGACTTGCTCAGCATCGTCTACCATTGTTAAGACAAATTATACAAAGCAGACATCTGTGACTGACAACTGTACAATAATATTAATCATATGTAATACTAAGAGATGGAAAAATAAATGTGCATAAGCAAAATAACCATTTTCATGGCTAATGATGTAATCTAGCTATAAGAAAATCATCAAACTAAGGATACATCCAAAACCAAAGTAATTTATCCCTGTCATAAACATTACCCAGACAGTATACAACACAGGGACCAGTGGTCTGTTTCCATCTTTTCAGGACTTTTCAGAGAAGTCGACGTGTCAACAGTTTTACAACTGAAACCTTCTAAGGAAATTCTCTGTTATAAAGTATCCAGAAAATTTCATTTAACATTAAGATGTAAACAGTTAACATTTCATTTCATCTTTAGTAATTAAATATCACTCTATTTGACCTTATTTAGAAAGTTTTATATGTAAAACATTTTTAAATTATCCCTTCTCAGATTTTTATACGAAAACAAAGATAAAGGAAAAAAACTTTTAAAATGTAATTGCTACTATTGCTATCTTTCTGCAGGAGTGTGTAAATAGACATGACACCCCACTGGCTGTATCAAACAATGGAGAATTTTCCCTGTGGTGGGGGCATAAGTTATCTTTAACATGAATGGTTTATACTGCAATTTACCCTCCATTTACATCTCTCTTTCAGCTGGACTCTGACTCAGACCGCATTGGAGATACCTGTGACAACAATCAGGATATTGATGAAGATGGCCACCAGAACAATCTGGACAACTGTCCCTATGTGCCCAATGCCAACCAGGCTGACCATGACAAAGATGGCAAGGGAGATGCCTGTGACCACGATGATGACAACGATGGCATTCCTGATGACAAGGACAACTGCAGACTCGTGCCCAATCCCGACCAGAAGGACTCTGACGGTGAGTCATGGGAGCCACTTTCTAAGACAGGGACTGCTGGCACAGCTGTGTAGATTGAAGAAATGAAACCAAGGCTCAAAGCATTTGACAGGATGAAGGGACCAAATGCCAACTTAGACAAGATAGTGACATTTCTGACACCAGTAATAATAATAGCACTTTAGAATTTTGCTGAACTCTTGCTTTTTTGACCTCAGGCGATGGTCGAGGTGATGCCTGCAAAGATGATTTTGACCATGACAGTGTGCCAGACATCGATGACATCTGTCCTGAGAATGTTGACATCAGTGAGACCGATTTCCGCCGATTCCAGATGATTCCTCTGGACCCCAAAGGGACATCCCAAAATGACCCTAACTGGGTTGTACGCCATCAGGGTAAAGAACTCGTCCAGACTGTCAACTGTGATCCTGGACTCGCTGTAGGTGAGTAGCGAGTTCTTAGATCCTAAGAGACTGATGCATACATGGGGAAAAACAAATATAAAACCTGGCAGTTGTACCTATCCCTGTGGGTGCTGAGGATGTCTAGGAACATGATGGAGAACCTTCTGAAGGCTGCAGGTTTTAACCTGGCTCTGGGCTCTTCTTCCAGGTTATGATGAGTTTAATGCTGTGGACTTCAGTGGCACCTTCTTCATCAACACCGAAAGGGACGATGACTATGCTGGATTTGTCTTTGGCTACCAGTCCAGCAGCCGCTTTTATGTTGTGATGTGGAAGCAAGTCACCCAGTCCTACTGGGACACCAACCCCACGAGGGCTCAGGGATACTCGGGCCTTTCTGTGAAAGTTGTAAACTCCACCACAGGGCCTGGCGAGCACCTGCGGAACGCCCTGTGGCACACAGGAAACACCCCTGGCCAGGTAAGAAGCAAAGCCCTGGAACAGAGAGAGAGCTTATGGGTGCCTGACTAGCACTGGGGATGCTGTGCTTTGACCAAGACTCTGACCAGGGAGTCTTAGAAAGTTCCCAGCATCACCAGCTGCAGCATTGAACTCTGCTTTGTAAAAACATAATAGTGTTGAAAAGGGAGCTTGACCAAGAATTGCCCTGCAAATCCTAAGGTGCCTTCAGCCTTTTCAAACAAAAAAACCTCCTTCCCTCCTCTCTGTCTGCTTTATATGTGTGCTCAGTGGCACACAACAAATATGAGAGGACTTGGAAAAATTCCCCATTGCAGCCCTCTAACTTAGATCAGCTCAGTACCTTTCAAGCATTGTTTCTGATGGAATGAAATAGAAATCTTTACCTGAAGGAGCTGTGTTTCAACCTTTCCTTTTCCTTTTCCTTCAGGTGCGCACCCTGTGGCATGACCCTCGTCACATAGGCTGGAAAGATTTCACCGCCTACAGATGGCGTCTCAGCCACAGGCCAAAGACGGGTTTCATTAGGTACGATCATACTGATTCACTTTCACTTACAGTCACACTGAGGGACAAAAAGACAAAAAGTATTAAATAGCATTGTCACTAAACAAGATTTTTTTTCCCTGCAGAGTGGTGATGTATGAAGGGAAGAAAATCATGGCTGACTCAGGACCCATCTATGATAAAACCTATGCTGGTGGTAGACTAGGGTTGTTTGTCTTCTCTCAAGAAATGGTGTTCTTCTCTGACCTGAAATACGAATGTAGAGGTAAGAGCAACATCACCATGAATGTACACTGGACATCTCTATTTCAGACTAATATCAAGGATGACGGTTATGGGGGAGTCCAGTGTAAAGACTGTTTTGGAGACAGGGTTATTTCTATTTTGCTTTTGAGGACACAAGGACAAAAATGGAATAATGCCTAGGCACTGTGGCTTATGAGTTCCTGAGTCCTTAGCTATAATATTAGTTTGCTTAGCAATCTCTGTGCTCCTCATACACAGTGCAAAGGTAAGCTGCAGAAAAGCTCCTATATAATTTGGACTTCATTAATAATACTGTTCTTTACAATTATATATTTATATATCTTACTGCTTATTGTTTTATGCATGCCATCACAGCACGAGTTAGCATTCCCAACTTTTCCCTGTATACAAAGAAGGGAGAGGAATGTTGCTTTCATATTGGCATGTTAAATTAATGTTCACTATTAAACTTAGCATTTTTTTTCCTCATTCTTTTTTACTTAGTCATTACTTAAGCTCGCTGAGTCCAACACTGGCTCTACCACAAAATAAGTGCTTAATATATATTTACTGGGCCAAGGCCAGATACCTAAAAGATCAATGACAGTAGAGAAAGATGGTTGATTTTACTCAAAAAAATCTAAATTATTAATGTAATTTTTGAGTCCAAATTTTTAAAATAAGACTCCCTAAACTGTTAACATTGAAAGCCTTTGGAAAGCATAATATATGTTCTGGAAGGTTCACGCTGTGTCGGTCTCCTAGCATCAATGTCAGCTAATAAAATTAAATGCTAATGTGCTTGAACAACCTTAAAATTAGGCTTTTGTCATTAGAAAAGTAGAGCTATTCCTATGTGGTTAACTTATTAACTAAGATGTCTATGCTTTTATGAATTAGTTTTCATTTGTATATTTATTTATATTTGTTTATTTAACAGATCCCTAATCATCAAATTGTTGATTGAAAGACTGATCATAAACCAATGCTGGTATTGCACCTTCTGGAACTATGGGCTTGAGAAAACCCCCAGGATCACTTCTCCTTGGCTTCCTTCTTTTCTGTGCTTGCATCAGTGTGGACTCCTAGAACGTGCGACCTGCCTCAAGAAAATGCAGTTTTCAAAAACAGACTCAGCATTCAGCCTCCAATGAATAAGACATCTTCCAAGCATATAAACAATTGCTTTGGTTTCCTTTTGAAAAAGCATCTACTTGCTTCAGTTGGGAAGGTGCCCATTCCACTCTGCCTTTGTCACAGAGCAGGGTGCTATTGTGAGGCCATCTCTGAGCAGTGGACTCAAAAGCATTTTCAGGCATGTCAGAGAAGGGAGGACTCACTAGAATTAGCAAACAAAACCACCCTGACATCCTCCTTCAGGAACACGGGGAGCAGAGGCCAAAGCACTAAGGGGAGGGCGCATACCCGAGACGATTGTATGAAGAAAATATGGAGGAACTGTTACATGTTCGGTACTAAGTCATTTTCAGGGGATTGAAAGACTATTGCTGGATTTCATGATGCTGACTGGCGTTAGCTGATTAACCCATGTAAATAGGCACTTAAATAGAAGCAGGAAAGGGAGACAAAGACTGGCTTCTGGACTTCCTCCCTGATCCCCACCCTTACTCATCACCTGCAGTGGCCAGAATTAGGGAATCAGAATCAAACCAGTGTAAGGCAGTGCTGGCTGCCATTGCCTGGTCACATTGAAATTGGTGGCTTCATTCTAGATGTAGCTTGTGCAGATGTAGCAGGAAAATAGGAAAACCTACCATCTCAGTGAGCACCAGCTGCCTCCCAAAGGAGGGGCAGCCGTGCTTATATTTTTATGGTTACAATGGCACAAAATTATTATCAACCTAACTAAAACATTCCTTTTCTCTTTTTTCCTGAATTATCATGGAGTTTTCTAATTCTCTCTTTTGGAATGTAGATTTTTTTTAAATGCTTTACGATGTAAAATATTTATTTTTTACTTATTCTGGAAGATCTGGCTGAAGGATTATTCATGGAACAGGAAGAAGCGTAAAGACTATCCATGTCATCTTTGTTGAGAGTCTTCGTGACTGTAAGATTGTAAATACAGATTATTTATTAACTCTGTTCTGCCTGGAAATTTAGGCTTCATACGGAAAGTGTTTGAGAGCAAGTAGTTGACATTTATCAGCAAATCTCTTGCAAGAACAGCACAAGGAAAATCAGTCTAATAAGCTGCTCTGCCCCTTGTGCTCAGAGTGGATGTTATGGGATTCTTTTTTTCTCTGTTTTATCTTTTCAAGTGGAATTAGTTGGTTATCCATTTGCAAATGTTTTAAATTGCAAAGAAAGCCATGAGGTCTTCAATACTGTTTTACCCCATCCCTTGTGCATATTTCCAGGGAGAAGGAAAGCATATACACTTTTTTCTTTCATTTTTCCAAAAGAGAAAAAAATGACAAAAGGTGAAACTTACATACAAATATTACCTCATTTGTTGTGTGACTGAGTAAAGAATTTTTGGATCAAGCGGAAAGAGTTTAAGTGTCTAACAAACTTAAAGCTACTGTAGTACCTAAAAAGTCAGTGTTGTACATAGCATAAAAACTCTGCAGAGAAGTATTCCCAATAAGGAAATAGCATTGAAATGTTAAATACAATTTCTGAAAGTTATGTTTTTTTTCTATCATCTGGTATACCATTGCTTTATTTTTATAAATTATTTTCTCATTGCCATTGGAATAGATATCTCAGATTGTGTAGATATGCTATTTAAATAATTTATCAGGAAATACTGCCTGTAGAGTTAGTATTTCTATTTTTATATAATGTTTGCACACTGAATTGAAGAATTGTTGGTTTTTTCTTTTTTTTGTTTTGTTTTTTTTTTTTTTTTTTTTTGCTTTTGACCTCCCATTTTTACTATTTGCCAATACCTTTTTCTAGGAATGTGCTTTTTTTTGTACACATTTTTATCCATTTTACATTCTAAAGCAGTGTAAGTTGTATATTACTGTTTCTTATGTACAAGGAACAACAATAAATCATATGGAAATTTATATTTATACTTACTGTATCCATGCTTATTTGTTCTCTACTGGCTTTATGTCATGAAGTATATGCGTAAATACCATTCATAAATCAATATAGCATATACAAAAATAAATTACAGTAAGTCATAGCAACATTCACAGTTTGTATGTGATTGAGAAAGACTGAGTTGCTCAGGCCTAGGCTTAGAATTTGCTGCGTTTGTGGAATAAAAGAACAAAATGATACATTAGCCTGCCATATCAAAAACATATAAAAGAGAAATTATCCCTAAGTCAAGGGCCCCCATAAGAATAAAATTTCTTATTAAGGTCATTAGATGTCATTGAATCCTTTTCAAAGTGCAGTATGAAAACAAAGGGAAAAACACTGAAGCACACGCAACTCTCACAGCGACATTTTCTGACCCACGAATGATGCCTTGGGTGGGCAACACGATTGCATGTTGTGGAGACACTTCGGAAGTAAATGTGGATGAGGGAGGAGCTGTCCTTGCAATGTTGAGCCAAGCATTACAGATACCTCCTCTTGAAGAAGGAATAATAAGTTTAATCAAAAAAGAAGACTAAAAAATGTAAAATTTGGAAGGAATCCATAAATGCGTGTGTGTCTAAATACAAATTATCATGTGAAGAAAAGGCCCAAGTGTACCAATAAGCAGACCTTGATTTTTGGATGGGCTAATTATGAATGTGGAATACTGACCAGTTAATTTCCAGTTTTAATGAAAACAGATCAAAGAAGAAATTTTATGAGTAGGTTAAAGGTCTGGCTTTGAGGTCTATTAAACACTAGAAAGGACTGGCTGGGTGAGATAAAATCTTCCTTGTTGATTTTCACTCTCATTCTATAAATACTCATCTTTCTGAGTAGCCATGATCACATACAAATGTAAATTGCCAAATCATTTTATAGTACCAAGGTGAAGAAGCAGGAACTAGAAAGTGTTGATAATAGCTGTGGAGTTAGGAAAACTGATGTGAAGGAAATAATTCTTTGAAATGGCAAAGAATTAAATACCATCATTCATTATCAGAAGAGTTCAACGTTTGAAGTGCTGGGAGATAATTCTAATTCATTCTTGGATAGTGAAGCAAAACTGATTGAAAATACCAAGATAAGACAGAAAAAGTGACTGGAAAGAGGAGCTTTTCTTCCAGGCATGTTCCAGTTTCACCCTAAGACTGACCTTCAAATAATCAGGTTGTACTGAAATAAAGGACTTGTTAAAAATTAAAATTATGTCATCGAGATGATAGCTTTTTTCCTCCTCCAACAGTTTATTGTCATGTGTTGTGGGAGAGCTCGAGTGAAGAGCAATAAACTCCAGGTCTTATAAGAATGTACATACAATAAAGGTGGTGCCAGCAGTTTTTTTTTTTCTAAAGAGTCACATGTAGAAAAGCCTCCAGTATTAAGCTCCTGAATTCATTCCTTAAATAAATTGGCTCTCTCTCTCTTCTATAATTTCTTTTTCTTTTTATTTTTGAGATGAAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGACACAATCTCGGCTCACTGCAACCTCTGCCTCCCCGGTTCAAGCAATTCTCCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAAGCGCCCGCCACCAAGCCTGGCTAATTCTGTATTTTTAGTAAAGACGGGGTTTCACCTTGTTCCGGACAAACACTAAGCCCTAAAGGGAAATCCAAAATAAAAACATCTATTTTTAATAACACTTTCTATCTAAATCAGGGTGACTTTTTAAAAAAAATCCGGAAGCTTTTTGTTGAATTACGTTACAGACTTAGTTACCAGTCCTTGTTAGAGTTACCTTCAGTTGACATGCTGTGAATGGTCCCACCTCTTTTATGGCAGAATTCATTACTTAAAATAACTCTATTTTCTTCCCCCTTACCTAAATAACAGAAAGGCTCACTATGTCCCAAATATCATTGGCAGAAGCAAACTATAAAGTCATAAGCCCTTTGCAGTGCAAGTCTAGAAATAATTTT

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