Details for gene: SLC39A5


The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]


Symbol
SLC39A5
Name
solute carrier family 39 member 5
Entrez ID
283375
Ensembl ID
ENSG00000139540    (more details)
KEGG ID
hsa:283375    (more details)
OMIM ID
615946
Uniprot ID
Q6ZMH5  
GO ID
hsa:283375    (more details)
Chromosome
12
Strand
1
Start
56230049
End
56237846
miRNA Interactions
hsa-miR-26b-3p (RPM: 23.5016) / hsa-miR-146a-5p (RPM: 774.8698) /
Involved Diseases
myopia /
Involved Pathways
Alzheimer's disease / Parkinson's disease / Transport of small molecules / SLC-mediated transmembrane transport / Transport of bile salts and organic acids, metal ions and amine compounds / Metal ion SLC transporters / Zinc transporters / Zinc influx into cells by the SLC39 gene family /
Sequence
CTGCCTGCCCCCCCAGCTGGAACCAAGAAGGTTGTGTCCCCCTTCCTCTGGGTGTCCTTGTCTCCTGCTATCAGGTAATGCCAACCTCAACCCCCTGGACCAGTCACCCCGATCAGACTTTGCTTGCCTGATTTTAGGCCAGGTCAGACATCAGAGGAGAGCCCAGATCCTTGTTTCCTCTCCCCCCGCAGGGCTTCCCCTTTCTTGGTCATCGATCCCTAGAGCTCTGGCTCTTTCTCTTCTTGGGGTGAGAAACTGCTAAGAACAGTTTATTTCCCATGCATGCATCTGGGCTTGCCACTGATCTGCCTTTTCCCCCCTCCTCCCCAGGTTAGGGACACCTGGGTCCAACCTTCCCAAGGAATATGGGGATGGGGGTTGGAGATGAAGTTTAGTGCTAGACTGTAAGGTAGGTGGGGTGGAAGTACATGAGGGAAAGGGCTAAAATGGTACTAATGGTGTTAAGGATAGGGTGAATTATTTAAGAGGAAAAAGACTAGGCCCAGGTTCTCCTTAGCCATGTGGCTTTCCCAGGGCAGAGGGTGGCCCCTCCCTACCCAGGGGCCCAGCAGAGACTGACTTTTGATCCCTACCCCAGAGACCAGTGAACCATTAACTCCTCTCTTATGTGAGCCTTCACACACTGGCCCCACCCCTGACCCCGCCCCAAGGCAGGTGGGCTAGGAGGGGGTGCATGTCCATCTCAGCCTTCTATGTGACGTGGCCTCCGATCCACCTGGACACCTGGAGGCTAAGCCTGGATTCCCCCTTCCCTGACTCAGGAACTGCTTAACGTCTACAGCAAGGCCTAATAGGGGACCTGAGGTGACAGCTCTTATGTTGCCAGTAGGGGTGAGGCCCTGGGGATTGAGGGGGGATAAAGAGGTGGGGCAAAGTTGAGGGGTGGGGTTTAGGGGACAAGGAATGGACGGTCAGCTCTGGATGAAGTATGAGGAGAGCTCTGACTCAGGGAGGTGCTCCAGGAACCAGCAAACAAGAGGCTGCTCCCGCAGGAGGCAGTGTGAAGGGAGAAAGAAGGCTGCAGTAGGGGCTGCTGCTGGACTCGGTGGGGAGCAGGTGCAAGGAGCTCTGGCTCCCCCATGGACCTGAGCTGGAGAGCAGAGCGCAGCTCCAGCCCATTCCTCATTCTTCCAGGGCACAGTCCTCAGGATGTTTCGGGGAGAATAGGAGCCAGAACCTGAGCCCCTAAGCTATTCCCCTCACCAATGATGGGGTCCCCAGTGAGTCATCTGCTGGCCGGCTTCTGTGTGTGGGTCGTCTTGGGCTGGGTAGGGGGCTCAGTCCCCAACCTGGGCCCTGCTGAGCAGGAGCAGAACCATTACCTGGCCCAGCTGTTTGGCCTGTACGGCGAGAATGGGACGCTGACTGCAGGGGGCTTGGCGCGGCTTCTCCACAGCCTGGGGCTAGGCCGAGTTCAGGGGCTTCGCCTGGGACAGCATGGGCCTCTGACTGGACGGGCTGCATCCCCAGCTGCAGACAATTCCACACACAGGTACTGACCCCTTCCTCCACTCCACAGGGCCACATCTCCCAGGTCCTCTCAGTGCTTGCCCCCAGTTGCCTCGTTCTGGCTTCCTCACGAGATCCCTGGAGTTACAAATTCTTCAGAACCGAGCTCCTTGGTATCTCTTCAAAACCTCTCATGCTTCTATTGCCTTCTCTCTCTTTTCTTGAGACTGGGGGTCTCGCTTTGTCACCCAGGCTAAAGTGCAGTGACACATTCACGGCTCACTGCAACCTCTGCTTCCCAGGCTGAAGCCATCCTCCCACCTCAGCCTCCTGAGCAGCTGGGACCATAGGCACACACCACCACAGCCGGCTAATTTTAAAAATTTTTTACAGAGACAAGGGTTTCGCTGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAGCTCAGCGATCTGCCTGCCTCAGCTTCCCAAAGTGCTGGGACTACAGATGTGAACTACCACCCTAGCCCTCCGTTGCCTTCTAATTCTCTCCTCCTCCAAATCTCTAAGCCCTTAAATTTCTTGCTCTTAGTATCACTGTTCAGTGTCTCTGGGCTGATTTGGCTCCAAATTCGTAGACTTCTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGTAACCTCTGCCTCCCCGGTTCAAGCGATTCTCCTGCCTCGGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCGGGCTAATTTTTGCAATTTTAGTAGAGACGGGGTTTCACCATTTTGGTCAGGCTGGTCTCGAACTTCCAACCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCATTCGTAGCCCTTTTGGTTGTCGTCCTTTTTTTTCTGTCCCCCCCAGTGGCAGAAAATGGACAACTCACAGATCTTCCTAAGAATGACATTCCATGGTTTCTGGGTCCCAGGATCTCCAGTCAGTGGCTAGTCCCCCCATTCCCCCTAAAATCCCTGGGAGCCTCTCAAAGCGGGTTGATAGAGAACACAAGGGAGGCTGACTTGCTGTCTCATCCATTCCAGGCCACAGAACCCTGAGCTGAGTGTGGATGTCTGGGCAGGGATGCCTCTGGGTCCCTCAGGGTGGGGTGACCTGGAAGAGTCAAAGGCCCCTCACCTACCCCGTGGGCCAGCCCCCTCGGGCCTGGACCTCCTTCACAGGCTTCTGTTGCTGGACCACTCATTGGCTGACCACCTGAATGAGGATGTGAGTCTGACGGTCTCTAGAGGGGAAGGAGCCATGGGATTAGATGGCCTGAAATGTTTAAATAATCAGTAGTTTTTTGTTTTGTTTTGTTTTTAAATCCCAACGTGGACCAAGCGTGGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAAATACAAAAATTAGCCGGGTGTGGTAACAGGTGTGTGTAATCCTAGCTACTCAGGAGGCTGAGGTGAGAAAATTGCTTGAACTTGGGAGGCAGAGGTTGCAGTGAGCCAAGATGGCACCATTTGCACTCCAGCCTGGGCAACAAGAGGGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATAGCTGGGCGTGGTGGCACATGCCTATAATCCCAGTTACTCGGAAGGCTGAGGCAGGAAAATCACTTGAACCCAGGAGGCGGAGATTGCAGTCAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTAACACAGCGAGACTCTGTCTCAAAAATGAAAATAAAAAAAATAAAAAAATAAAAAAAAAATATCTCACTGTGGTCTTAGGGGATGTTATTTCAATAGTGAACTATGTTCCCTCTGGGATCAGAGCAGGTGAGCCCATATCCAGAGCTCCAAGACTCAGTTTAGGGGAATAGATGGCAAAGCAGAGAATCTAGAGAAGCAGCCCAGGGTAGGATCTGGATGGTCACCTGGAGAGGAGACCTGCAGGGAATGGATGGCTGTCTTCATCCAGAAAGACAGAGAATATATTCCACTTACACCAGAGGGCAGACAAAGCTGCCTAACCCTGATGGAGGTCCAGTGAGTGCCCATTGCAGGAAGCATTCAAGCTGAGGCTGGATGAACATCGACAGGGCTGTTGAGAGGGAGATTAGATGGCATTTCAGGGTCTTTTCCCTTTTAAGATTCTGGCATGGAGAGCTCTAGTTTTCCAACCAGCTTCATTTATCAAATCAACAAAATGATTGAAATGATCAGAGTTTGCAGGGAAGATGATGACAATGCTCACTAGCACCCAGTTTGCATCAAATTGAATACCTGCATTGGACTGAATATTCACTAATAATACACATTGATTATAAGTACCCTTGGCCCTAGTCCCCAAGGTACCTGCCAGTAGGAGCAAAGGGGACCCTGGGAGAGACCCAGGAGTCTATGCAATGGAAGGACAGGTGTTAAATATATATATATATATTTTTTTGAGGTAGAGTCTGACTCTGTCACCCAGGCTGGAGTGCAATGGCGTGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTAAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTATAGGTGTTCACTACTATCCCCAGCTAATTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCACTGGTGCAATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATCACAGGTGCACGCCACCATGCCCAGCTAATTTTTTGTATTTTAGTAGAGACAGGGTTTCACCATGTTGCCCAGGCTGGTCTCGAACTCCTGAGCTCAGGCAATCTACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCTCATCCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTGGCCAGGTTGGTCTCAAACTCCTGACCTCAGATGATACACCCGCCTGGGCCTCTCAAGGGCTGGGATTATAGGTGTGAGCCACTACACCTGGCCAGGTGTTAAAGATCTGAGTCATAGTTCCTGGTGATTCTCCAATGTATGACCCTCAATTCTCCAGTGTCTGAACGGCTCCCAGCTGCTGGTCAATTTTGGCTTGAGCCCCGCTGCTCCTCTGACCCCTCGTCAGTTTGCTCTGCTGTGCCCAGCCCTGCTTTATCAGATCGACAGCCGCGTCTGCATCGGCGCTCCGGCCCCTGCACCCCCAGGGGATCTACTATCTGGTCAGCAAGTAGGAGTGGGTGGGGGACACCCTGAATCCTGGAAGTGGGGCCCATGCCAAAAAGGAGGCTCACTGGGGTCCTGCCTCTCCTTGTAGTGTTCTCTCTGCTCCACCTTACGTGTGGGACCCTCCTCTTGCCCTGACCTAACTTCAGCCCCTGATTCTCCCCAGCCCTGCTTCAGAGTGCCCTGGCAGTCCTGTTGCTCAGCCTCCCTTCTCCCCTATCCCTGCTGCTGCTGCGGCTCCTGGGACCTCGTCTACTACGGCCCTTGCTGGGCTTCCTGGGGGCCCTGGCGGTGGGCACTCTTTGTGGGGATGCACTGCTACATCTGCTACCGCATGTATGTGAAGCCCCTTCCTTGTACCCCTGGCCTCCATGGATCTAAGGTGTCCCCAGCCATAGGACATCCCCTCCGCCTTTCCATCAGCTCCCATATCCTACTCCCAGATCCTGGCTTCAGCCCACAGCTGCCTTCTAGTAGAGCATATGAGCGAAGGCTTGCCACAATCCATGCAAGGGGATGTTGTTGGGTATAGGGGCTTCCAGAGTCTGCCCTGACCTTCTCTCTGTCAGGCACAAGAAGGGCGGCACGCAGGACCTGGCGGACTACCAGAGAAGGACCTGGGCCCGGGGCTGTCAGTGCTCGGAGGCCTCTTCCTGCTCTTTGTGCTGGAGAACATGCTGGGGCTTTTGCGGCACCGAGGGCTCAGGCCAGTGAGTGATACCCTTTTCTCCTCCTTCTGCTGAGACCAGAGTCCCAGTCAAGAACTGGGCCAGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGCCCAAGGCGGGCAGATCACAAGGTTAGGAGTTCGAGTCCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCGTGTCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGACTTGGGAGGTGGAGGTTGCAGCGAGCTAAGATGGCACCACTGCACTCCAGCCCAGGTGACAGAGCGAGACTCCATCTCAAAAACAACAACAACAACAACAAAACTGGGCCAAAAAGCCAAGAGATGAGGAGCAGTGTGTGCTCCTGGATCTCTGACATTTGCCTGGTGTGCAGGACCTATCGGCTAACAGGGAGTGGGTAGGGGCTCCTTAAGCACAGACCCAGGACTTCTGGCCAAATGGCATCCTATTCTGAGCTCAAGTCAACAAGAAACAGAGGGGAGGTGCCAACTTGGGAAGAAGGTAGAGGCCAAAGAACATCCCAGGTGCCAGAGGTGGAACCAGGTGTTCATCTTCCCAGCTTGTGGCCTGGCTTCCCCTTAGTCCCTGGCTCTGCTGCCTCCTCCACCAGGAGGGATGCCCTCCTATTTCAGAGATGCTGCAGGCGAAAACGAAGGAATCTCGAAACACGCAACTTGGATCCGGAGAATGGCAGTGGGATGGCCCTTCAGCCCCTACAGGCAGCTCCAGGTGACTAGAGGAGAAAATTTGAAGAGTAGGTTCCAAGCTCACAGTCCTTACTTGCAGCCACCAACACTGTCCTGTGCTTCTTCCCGCAGAGCCAGGGGCTCAGGGCCAGAGGGAGAAGAACAGCCAGCACCCACCAGCTCTGGCCCCTCCTGGGCACCAAGGCCACAGTCATGGGCACCAGGGTGGCACTGATATCACGTGGATGGTCCTCCTGGGAGATGGTCTACACAACCTCACTGATGGGCTGGCCATAGGTGTGAGGGGTGGGAACGGAGGGAAGCAGGTCCGAGGGGAGGCCAGGGCTCCTAGTTATCAGCTGGGGCTAGGAGAGGGCCGTCAGGAAGATGGGGAGAGGACGGGAGGACCACGGAACACAGGAACCTGCTTCTGAGGAGACTTTTCTTCTGGACTGACAACTTCCGACCCTGCTGGCCCCAGGTGCTGCCTTCTCTGATGGCTTCTCCAGCGGCCTCAGTACCACCTTAGCGGTCTTCTGCCATGAGCTGCCCCACGAACTGGGTAGGAATGGCAGGAGCAGGGTGGGGTGGACTCCAGAAAGGAGATAGCTCCAAGGGGTAGAGCTTGGAGGCTGGTGGGTGGCATGGATGAGGGGCACCCCAGCTTACTCCCTCCCATCCTGTCCTCTGTCTCCAATAGGTGACTTTGCCATGCTGCTCCAGTCAGGGCTGTCCTTTCGGCGGCTGCTGCTGCTGAGCCTCGTGTCTGGAGCCCTGGGATTGGGGGGTGCAGTCCTGGGGGTGGGGCTCAGCCTGGGCCCTGTCCCCCTCACTCCCTGGGTGTTTGGGGTCACTGCTGGGGTCTTCCTCTATGTGGCCCTTGTGGACATGGTGAGAGATGTCGGGTAGAGCAGAGAAATCAAGGGCAGTGGGGAGGCGGGAGTGGAGAGGGAGGTAGCAGTCCCTCCGCCTCTACCATTAGCTCCTGGAAGGGCGTCAGACCATAGGCCCGCAAAAGTCTGAGAAACAAGGGACTAAGGTGTTTGGGTGGGGGCTGCTGATGCTTTCTGACACCATTCCTCTGGAGTTGAGAGGTCAGGGGCAAGGCCAGAATCCTGACATCCTCTTTTTCTTTCAGCTACCAGCCCTGCTTCGTCCTCCGGAGCCCCTGCCTACGCCCCATGTGCTCCTGCAGGGGCTGGGGCTGCTGCTGGGGGGCGGCCTCATGCTTGCCATAACCCTGCTGGAGGAGCGGCTACTGCCCGTGACCACTGAGGGCTGATGGGGCCAGTGGAAAGGGGTCGGGTTGCCCTTCCTTCCCCCCAACCACAGGAATGGAGGCGGGACACAGGGCCAGTAGGAGCAATAGGATTTTAATAAACAGAACCCATCCCAAA

Back to List