Details for gene: TDP2


This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]


Symbol
TDP2
Name
tyrosyl-DNA phosphodiesterase 2
Entrez ID
51567
Ensembl ID
ENSG00000111802    (more details)
KEGG ID
has:51567    (more details)
OMIM ID
605764
Uniprot ID
O95551  
GO ID
has:51567    (more details)
Chromosome
6
Strand
-1
Start
24649979
End
24666899
miRNA Interactions
Involved Diseases
Posterior capsule opacification (PCO) /
Involved Pathways
Sequence

Back to List