Details for gene: DHCR7


This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009]


Symbol
DHCR7
Name
7-dehydrocholesterol reductase
Entrez ID
1717
Ensembl ID
ENSG00000172893    (more details)
KEGG ID
hsa:1717    (more details)
OMIM ID
602858
Uniprot ID
Q9UBM7  
GO ID
hsa:1717    (more details)
Chromosome
11
Strand
-1
Start
71428193
End
71452868
miRNA Interactions
hsa-miR-133a-3p (RPM: 411.6588) / hsa-miR-30e-5p (RPM: 2305.0396) / hsa-miR-124-3p (RPM: 4110.4386) / hsa-miR-34a-5p (RPM: 81.3502) / hsa-miR-16-5p (RPM: 2473.4704) / hsa-miR-182-5p (RPM: 77446.6216) / hsa-miR-147a (RPM: 0.0014) / hsa-miR-107 (RPM: 234.4574) / hsa-miR-103a-3p (RPM: 2034.8158) / hsa-miR-1301-3p (RPM: 47.2112) / hsa-miR-125b-2-3p (RPM: 492.7724) / hsa-miR-200b-3p (RPM: 566.8348) / hsa-let-7e-5p (RPM: 3790.2074) / hsa-miR-7-5p (RPM: 19.3682) / hsa-miR-548n (RPM: 0.0924) / hsa-miR-203a-3p (RPM: 1346.5646) / hsa-let-7d-5p (RPM: 1078.3154) / hsa-miR-1-3p (RPM: 26.3428) / hsa-miR-378a-3p (RPM: 1540.7796) / hsa-let-7g-3p (RPM: 7.0448) / hsa-miR-660-3p (RPM: 0.609) / hsa-miR-4747-5p (RPM: 0.0074) / hsa-miR-4766-3p (RPM: 0.011) / hsa-miR-422a (RPM: 0.3564) / hsa-miR-425-5p (RPM: 187.631) / hsa-miR-4708-3p (RPM: 0.357) / hsa-miR-335-5p (RPM: 265.7294) / hsa-miR-374b-3p (RPM: 5.4276) / hsa-miR-1260b (RPM: 243.165) / hsa-miR-522-5p (RPM: 0.0018) / hsa-miR-218-5p (RPM: 36.775) / hsa-miR-210-3p (RPM: 361.0562) / hsa-miR-191-5p (RPM: 12993.8088) / hsa-miR-7156-3p (RPM: 0.0008) / hsa-miR-1268a (RPM: 5.2444) / hsa-miR-1268b (RPM: 5.7518) /
Involved Diseases
cataract /
Involved Pathways
Metabolic pathways / Steroid biosynthesis / Metabolism / Metabolism of lipids / Regulation of cholesterol biosynthesis by SREBP (SREBF) / Cholesterol biosynthesis / Activation of gene expression by SREBF (SREBP) / Metabolism of steroids / Cholesterol biosynthesis via desmosterol / Cholesterol biosynthesis via lathosterol /
Sequence
ATGAAACGTTCCAAATACACCAAAAGTGGAGAGTACGGTAGGAGCGCTCCATCGTGCCCGCGGGACAGCAGACGATAGCAATCGATTCTCCGTGCTGGGAATCCCGCCACCCTGGGCGGATGGCGCTGAATTCTTGGGAACCCTCTCCTGCCCCTTTCACTCCTGTACCACGTGTGTAAGTAGCTCAGGTAGCGCACTGTTTGCCTTTTCTGAAACTACAGGAACTGCACTTGAATGTGCTTCTGCAACTTGATTTTTTCCCCTGTAATATGAGATACGTTCTTTTAATTATTTTTCTGCAGTTTGGTATTCCATAGTGGCAGTAAAGCAGGTTTATTCAATAGCGGATGGGCATTGACGTTATTAGCAGCGTTTTGCCAACAGACGCACGCACACAGGCACTGCTGCAATTTCCTTTCCGGCAAGGTTTCCTTCGTGACCTCGTTCCGCCAGTTCCTGCAGCAGCTTTGCAGAGTAGTAGGGTTCGTGCTGTTTGACTTTACTAAATATTGCCAAGTCTCTTCTCCAGGGCGCTTGCACCGATTCACTACCAGCGGTTTCTCACTTTTTATTTTTTCACATTTCCTCTTTAGTCCACCCACGGTAGAATCCATTTTTCCCCCATATAAATAACTGCCTCATCATCGTTGCTTGAAGAGGCCATCCTTCCTTCTGTCATTCATGTTAGTTTAAAAACACACAATTCACAAATTTGGAAAAAGAGAAGGCTTTATTTCTTGTAAACGGTCGTAGCCTGCAAGGTGGCGGCCATCTGTCTGAGGCTGGGAATCTGTCTCCAGCCAAGGCCAGAGACAGGCACGTCCAAGGAGGAGGGGTTGGGGCAGGAGCGCTATGCTGAAGGGATTGGCTAAACATACATATTCAACAGGTAACAGGAGGAGCTATGAATATTCATGAAGGTGGTCCTGACACATGCCCTCTTATTGAGCAAAGCATGTAATATATGACCCATGTTCACTTTGGGGTGGAGACTTAACATTTACACATCTTACAATTAGGGCCTTTATGGCAAAACGTCTTTTCAGGACACAAAGGCATGCAGGTGCATCATCTCTCTCTATTAACGGGTCAGCTGGTCGGCATGGTCAGCTGGTCGGTGGTCTCTTATTAGGAGAAAGTCACTGAAATCAGTCTCTTGTCCAATCACAGCTGCTATGGCTGGTGAAACAGAGTCAGTTAGTTGGCACCTAGTGGAGCTGCAATTGTTTTAATATTCCCTATCCCAAGGCTAGTGTGTGTTTGGCTAATAGAGAAACAGAAAGCCTTGTGGCTCTTAGAATATAGTTTATTCTCTAAGTGTGGGTTGCCTGACTTACCCTCGCCTAGCATGGCTTTGGGTCCTGTTTATAATTTGGTATCTTATTGCCACAGAGTCCGTTCTGTCAGTCTTACGATCTCTGTTTTAACATGAATGCCGGCCAGTTGTGGTGTCCAAACTCTGAAACAGGGGGCTATTACCAGGCGCATCTGACCTCCCATCCCATCATGTCTGGGAATTCAGTGTTGAGGTTTTTCTGGTGTCCCCTTGGTCAGGAGAAGGTCCCTTTGGTCAATGGGGGGCTTAGGATTTTATTTTTACCTTATGTACATATACCCGTTTTCACATTTTGAATCACTTTTTTTCCTGTCTATAAAGTAGTGCTTGTTCATGACAATTTGGAAACTCCACAAAAGCACCAGAATGTTATACATGCTAACTTATTTAATCCTCACAGTAGTTTTCATGCTTCTGAAATCCACACGATCTGCTCAAATTATCTCCTGCCAACAATGGCTGATGCCAGGCCTGGGCAGAGAAGGGGAGGATCCTTGAACATCTGGTTGTCCCAGAAAATAAGTAAGTACTCAAAGGATGGTAGATACATGTCATATGAAAAAAGAAGCCAATTTGAAGGGGCTCCCGTTAGCTAAATACAGGACAATACAGTAAGGATCATAACTCGGTCAGCTAAATCCATTAGGGCATACTGATAAAAAATAAATCAAAGAGGAAATCCCTACAGAAGAATGCTTGCTAATAAATAATTTATTAATAAATGTTGAGGGAATGATAAAATTAGAAAATTAACACTTTGTCCCAAGAAATAAGGGATTCAGGCAAGATTCCTCATTAAATGCTAGTTCACTGGGTGAAAGGTCATTTGGGAACAGCATATTTACAGTCTCAAAGTATCACTGCACCAATTACTCATTAATAACAAAAGGAAAAATGGAGACTTCTGGCAGAAACCACGGAGCCCCACTATCAATCATGGAGCACAGTGATATGTTGTCTTAAAAAAGAAAATTTTAGGACTCTTGAAATTTATTAGGTCAACTTGGGCAACAGAGCAAGATCCTGTCTTTAAATAAATAAATAAAAATAAATAAATTTATTATGTCAAGAGGGAAGTTAAGTCCTAGAAACTGGGTCACATAGCATGTTTGTAATTTTGTCTTTTAGATTATAGGCTGTTTTTCTTTATCATTCATGTTTTATAAATGACTAGGAGAGACCACAGACCAGGCCTGCTCCCCTTTTAATTACTGATCTTTATTATAGATTGTCTCTTATTATCCCGTACTTAGACCAGACTCCTACATCTTCAGTGTAAAATGTTAAATATACCTTCCACCTAAAAAAGACCACCTCAGCTGGTCAGATTATAACTTTATGCATAAAAAGATGTTAAAATTCTGTTAAACTTCCCTAAAATTTGTCTACATAAATGATCCCAAACATCTACAGTTCAAAATACTGATTTCCATTCTTTAAAATCTGTGCTTCCCAGGCAGCCTGTCCTCAAACTTTATACACTTAAATAAACTCTCTTTAAGCTAAATTCTGACCTGTTTGGTTATTTCAGGTTGACAGCCTTCTAACAAGATAAAACATGCTCTATGTAGTATATTATCCTGCCAAAAAAAGTGCATAGCCTGAATGCACAGTGTGGCTCCCTGATTAGATCCTGGGGTTTAAAAAAGGGCTGTAGGGCAGAGCTTCACACCTGTAGTCCCAGCACTGTAGGAGGCCACAGTGGGTGGATCGCTTGAGCCCAGGAGTTCGAGACCAGCTTGGGGAACATAGTGAGACCCCCCCCCCCACCCATCTCTACCAAAAAAAAAATAGCGTGTGGTGGTGTGCTCTTGTAGTCCCAGCTACTCAGGAGGGTGAGGGAAGAGAATCGCTTGAGCCCAGCAGTTCAAGGCTGCAGTGAGCTGTGATCGTGCCACTACACTCCAGCCTGTGTGACAGAGACCCCCGTCTTAACAAAGCAAAACAAAACAACAATAACAAAAGGGCTGTAAAGGGCATTATTGGGACAACCGCGGGAAACTGGAGATGGAAAATAGATAACAGCATTGAACTGATGTGGTCATTGTATTTTGGTAATATAGGAGGTTCTTGTTCTTAAGGAGTTGGATACCGAAGTATTTGGGAGGGGGGTATCACGGTATCTGCAGCTAATGGTGGGGGCTGAGTGGGGAGGAAAAAAGAAAAATACACATATATAAACACAGAGGGAGAGAAATGAAACGTGGCCAGCTGCTCACCCCTGCTGAACCTAGGAATCTGCGTGCTCACTTTACGTTCAACTTGTTTGTATGCTGAACATTTTTCAAAACAAAAAGGTGCAGGGAAAAAAGAAAACATGATGTCTCTCTGAGGGCCACAGAGACGTGGCAACCAGATCGCTCTGACAGTAAGGCCTGTTACCCGAGCTGTTGGGTGTGGGGTCAGCAGACACCTTCAGCTGCCCCCTCCTCCAGGGCTGCCTCGCCCCAGGTCATGCCCTCGCAACGTGGCCCGTGCGTCCGGCTCGCACTGTGGCTCAGCTTCTCCCTTTGCCCAGTCCTGCTGCTCCCTCCCCTCCCGTCCTCGCACAGGTGTGCCCCCCTAATAAGCAGGCCACCCAGACTCCATCTCGGGTCACTTTGGCGGTCTCCCAGCGGCGAGCCTTCCCTGACACCCATGTGTTTACCTGATCGTTTATGGAGGATCCTCTTCGCCCCGGGACGTGAGCCCTAGGACCAAGAACTGTGTCTGTTTTGCTCCTTGCGGTGCACCGGCGCCTGGACATACGCTCCATCAATGTGCGTCGCGAGCCGCTGAAGCCCCATTTGCCGAGGGGGAAACTGAGGCACGATGATCCAGGTGATGAGCCTGGCGCGTTCTCCGCGCGGCCCACGTGGCCACTCCGCCACGCCCCACCCCCAGCTGGTCAGCTGGGATCCCGAAGAAGCGCCAGAGGCTGCGCCCACCCACTAGGGCCCGGGCGGGCCGGTGGGGCGGCAGGGCGGGGCCTGGGCCGTCAATCTCGAGTCCGGCCGCTGCCGAATGGCGGGCGCGGTGGGCCCGGAGTCAGCTCAGGCTCCTCGACCAATCACGGGGCGCGGAGCCGCCGGGCGTGCAGGGTCCGCCTCCGATTGGCAGGCAATCGCTGACATCATCCGGGGGCGGGCGCCCCTGCCCTGCGGGTGACTCCGACCCCTGGCTAGAGGGTAGGCGGCGTGGAGCAGCGCGCGCAAGCGAGGCCAGGGGAAGGTGGGCGCAGGTGAGGGGCCGAGGTGTGCGCAGGTGAGTGGCCAAGGTGTGCGCAGGTGAGGCCAGGGGAAGGTGTGCGCAGTGGGGGGCGCTTGCCCAGGTGAGCAGGTGCCCACTCACAGGGCGAGGGTGGGGTCAGGGGTAGGGGGCGTGCGCGCAGGTGGGGAGAGGGTCCAGCTCACAGGCGAGGGGCCGCTGGGGCTCCGGGGAGGCGGGGCGGAGGCGTGGATAGTCCCCCTCCCCCACGAGCCGGCGTCTGAGGGATGCTCTGTCCCCGCGCTGTCTGGAGCTTCCCCGGGCGAAGGCTGCCTGGCTCCGGGGTCGGCTCCTGGCCCCATGCCGCGCTCCGCGGCGGCTCTTTCTCCTGCCCCACCTGTTGTTCGCCTCCCTCTTTGTCAGTGCTGAGCCAGGCACAGCAGCTTTGCGATGGGACTGGCTTGTCCGCCGTCCTCCCTGACATGCGGCTGTTGAAGCCCTGAGCACTGGACCTTCTGCCTCTTGCTTGACTCCTACTGTGGGCCTTGAGCTTCTGCCCTCTCCTGAAATGTCAGCTGCCTGCGGTCTTATTCATTTTTGTGTTCCTTGCAGGACTTTAGCCGGTTGAGAAGGATCAAGCAGGCATTTGGAGCACAGGTGTCTAGAAACTTTTAAGGGGCCGGTTCAAGAAGGAAAAGTTCCCTTCTGCTGTGAAACTATTTGGCAAGAGGCTGGAGGTAAGTGTATCTCAGTGCCCTGGATCGTGGGCGCAGGCTATGGCTTCACAGCGTTGAAAGTACAGACAGACTGGTCCACCAGCTCTCGAGTGCCAACGACTGTCTGTGCCTCTTATGAGTAAAATACAACATACCAGGGCACCTCCCCTTTGTCTGTTCCCAGCCGTCTATTGGGAAGGATGTTACTTAGATGTTTATTGCACAACTCAATGCTTGTGGCTAAAGAGCTGACTCCTGGGTGAATGAACTCTGTAATAAGCTAAAAGTACTTCTTTGGTCTTGTTTTAATCCCTTTTGACAACATTCTCCCAGTGGCTTTTTCACACTTTAGTTCTGAGGTTACACATCCCCTGACCCTTTTGCAATTTCCCAGTGTTTTACATAATTGATAATGTTGGTACCAGGCATTGTCCCCTTGTAGCTTATCCATGGCTTGGGGCAAGACGAATGCCACCCCATTCTACTTAGCCTTCCTGTAAGGCAAGTGTGCATGTGGGTGGTCTGGATTAACACCAGTCAGTGTGGGAACTAGGGATCGGAGGGAGTGGGGGCACTGAGCTGGTAAGTTTTGGCTGGGAAGAAACTAAGCTTGTATCTTACCTTGATGAGAGCCTGGGGGAGAGGAACTGTCTAAAGCAAGCCAGCTTGTCCAGGTGGCTGTGATCTTGAGATCAGACTCACTAGCGTGTCAGCTTTTCTCAGAAGTAGTTTTCTTTCATCCACTTTGATTTTACAGATATAAGGAGAGTGACTGGCACTCGCCAGGCTCTGTATTCAGTATTTGGGGCCGGAGAGAGACACGGTCTCTTCCTATCAAGAACTCTTCGTCTTGTTTTGTGCATCATAGGAACTGCATAAACTAACTTGTGTAAATTGAATGAAGTGCGGGTACTGAAGTTCTCACACTGCATAAGGAAAATGTCTTTCATCGTTGAAATTTTTTAAATGTGTGTGAATTTTTATTAAAGTAATTCATGCACACATTTTTTTAAAAATCAGTGTTAAAAGGCTTCAGAAGAAATACTCTCTACCACATCCCACATCCGACAGTCTTGCTTGCCAGCAGCAAACACTTTTCATTCTTTCAGCTACTTTTGTGTTGTTGTTTGTACCTACTTGTTTCTAAGTAATTTCCTTTTAGTACCCCTAACTTTGCAAATTCCCTTCTGTGCATACAATAGTCAATAAATAGTCAGAGTATACATTGTTATGACAAAATTACCATTATTCACTGTTGAGCCAAGTAAGGTCCTATAATAATGGCTTGGTTTCTTTTTTTCCTTCCTTATATGACTTTTTATTTTTCCTGGAGTTAACAGTTGCCTTCCTTTTTTTTTTTTTTTTTTTTTCATTTGGTAAGGTTTCTATGCATCTCTCATTCATTTTTTTCTGGATGCTCTAACCGAGCTGTCACATATATCAATAATTTTCCTACACATTCAGATGCAACAAAATTCATCATTTTCATTTCCTCTCTTTCCTAGCCATTCATCTTGTACCAATGTGGACTGGTTTCTGGTTAGTCCTGCTGCATAGCTGTCCTCTTGGGACTTGCCCCTGCCCTTTTGTGGACATGGCTTCAGCAGCTCTCTTGGGTCTCCAGTTTCCTGGATCCTATGTTGTTGTCCTTGAGTAATAGTTCACATAGGAGTAGAATTCTAGGTTGCAAAAAGTTTTCCTCAAAATTTTGAAGTTTTTCATCATTGTCTTCTAGAATCCAGCTTGCTGTTGAGAAATCTAAGCCTACTGTGATTTTTACTCCTGTTTTTTCTCTAAAAGCTTTCAAGAGCATCTTTTAAAAAATCTCAGATATTTTAAAGCTTCACAGTTATGAACTTGTTCTGGAAGTGGGGATGTCACTGCTTCCCCCAAATTATAACCATGTAGAGCAGCTGTGGGTACCTAGAGACATTCTGTGTTCTCTTCCCCTTTTTTTTGAAGGGTGATTATTGATGGTCCTACATGGGCCACTGTTCTAGGCCCTGGTAGTAGAACAATGAAGAGGACACACAATTCCTGCCCTTGGGAAGCTTACATTCTAGTGAGGGGAGACAGACAATACACACACACAAATGAATACTTCTAGGCGATGGGGAGAGTTACTAAGAAAATAAAGTACCCAGTGGAGGGCCTTGGCAGGGAAGCTGGGGAGCAGCTGCTTCAGATTGGCTGAGAGGGAAGATCTCCCCAGGAGGGGACATTTTACATGAGCCCTGAACAAGGACACCTGCAAACGTGCTCTAAGCAGAGGAAGTCAGTGCCACAGACAATTTAAACTGTGTTCAAGGATGAGTGAAGACCCCTGTGTTCCTGGAGCCAAAGGAGAATAGGGGAGAGTGGTGTGTAGGAGGGAGGCAGGAGCCAGCTTGTGCTGTAAGAGGGGGGGCATTCTGCCATGTTTGGAGAATGAACTGAGACTAGCAAGAGCAGCCATAGCAAGGTCACGTGGGAGGTGATTGCAGGGTCCAAGGAAGAGAGTCTAAGACAAGATGATCTCTTCCCTGCCTGGAATCTGCTGTCAGGAACAAGGTACCGGGAAGATGTGCACAGGAGGCCAGCCCTGCCAGGCCCAGGAGCAGTGGTGGATGCAACAGGGAAAGGTGGTGTCTGTTATTTGAGGGATAATGTAAGCAAGGTTCTCTTTCTTGCAGGGCCCAATGGCTGCAAAATCGCAACCCAACATTCCCAAAGCCAAGAGTCTAGATGGCGTCACCAATGACAGAACCGCATCTCAAGGGCAGTGGGGCCGTGCCTGGTAAGGATCTTGCCTGTTCTCCCAGCTAGAAAGTAAAGTGTGGTCTCAGAGCTTTCCAGCCTTTGGAATTGTATGGACCCAAAGGAATGAAGGACCTTTTTAAAAAAGATTTTTTTTTTTTTGTCAAGACTAATGAAAGGTAAACAGTTTTCCACTTTATAAAGTAAGGAATTATAAAAAGAAACTAGAAATCATGGTCAGTCAACAACTTAGAAAAAAAGATAAAGGCTTAAAGGGCAGCTGGGGCCTTCCCACCATCTGGGGGTATGACCTATTGTCACAGCTCCCATTTCGCCATAGAACCATGGGGACTTCGTGCAGGGTGAGTATCCTCTCCGACCTGGAACTGGGGAAACCACTGGCCTTGGTGGTTGTGAAAGACCTACCTCCGCTCATATTCTGAGCTCTGGGCCTTCCATGGGGGCCACAGATAGTGCCACCAGTTAATCAACTACAGTAGAGCAGGCATGTTGAGTGGCTTCCCTGGCCGCAAGGAGGGCCCGTGCTAGGAGCTAATGCCTTCTGTCATGGGGTACTGGTGGGTTTGAGCAACAGTTCTCCCACACAGAGCCTCTTAGGGTCCTGGTGGGGCCCAGGGCAGATGGGCCCCAGTGTGACTGCCTGCATCCGTCCTCGCAGGGAGGTGGACTGGTTTTCACTGGCGAGCGTCATCTTCCTACTGCTGTTCGCCCCCTTCATCGTCTACTACTTCATCATGGCTTGTGACCAGTACAGCTGCGCCCTGACTGGCCCTGTGGTGGACATCGTCACCGGACATGCTCGGCTCTCGGACATCTGGGCCAAGACTCCACCTATAACGAGGAAAGCCGCCCAGCTCTATACCTTGTGGGTCACCTTCCAGGTCAGCAGCCCCTGCCCTGGGGTTGGGACACAGCAGGTGGGGAGCGTGCCCTCCTGCTGGGGTAGTCCTTCCATTTGTCTGGGACATGGATCCTGGCTCAGGTTGACATCTGGGTTCCCGGGACCCAGCAGGGCATTCCCTGGACTCTGACATGTTCAGATTCATCCTCAGCTGTAAGGCAGGAGGCACCTGTCACATCAGCGTTTGATACACCTTCACGGCATGCCTGCATGCAGTTGCTGGGCACGCCCAGCTCTGCAGGGACAAGCTGAGGATAGGAGCAAAACCCCGTGGGAGGGCAGTGCTGTCCTGAGGAAGCCCCATTGTCAGCAGGAGTCACGCCTTGCACCAGGTCTGGAAAGGAGCATCTCAGTCCCCAAAGGGACTCTCTCAGTCATGAGATGCCACTCAGAGAAGCGAGGGCCATGTTTCCCCACAGGCAGTCGAGGCAGGTCCAGGACGTCCTCAGCTCCATGGTGTCCCCACTGGCCTCCCAGTCCAGAGGGAGTTCCAGGAAGGGGTTGTTGTAAACCTGGTGCACACATGGGTGGTGCTGATTGCCTGAACCCAGGAAAAGGTTTCCAGGGAAACGGTGCTAGAAAGAGACAGGCCTGGGTTTTCCTTCCTGGGCGGGAGGAAGGCTCAGATCATGATTAGCTGTTTCTCCCCAGGGTCCAAGCTTCTGGGCTCCAGAATACTTCTCAGTTCAGATCTCTTGGTCCCTTTGAGTGAAAAATGACAGGGGCAGTGTGAATCACAAATAGCCACAAAGCAGGAACCCCCACCTGTCCATCAGTAGATGAATGGACCCACAGAACAGAACACTGTGCCCACTGTGGGACACTATTTGGCAGCGGAAGGGAATGAAGCTCTGATGCCAGTAGGCGGATGACCCTTGAAGACACTGCTGAGCGAGAGAAGCCAGTCACAGAGGCTGCATACTGTGTGGTTCCCTTTATATGCAATACCCAGTACAGGCAAATCCACAGAGGCAGAAAGCTCAGTGGCAGCCAGGGGCGGCAGGGACAGGGAATTCAGAGTGACCGGAGATTGGAACAACATTTTCTTCTGTGGTGATGAAAAGTTCTGGAATTAGCAGTGATAGGTGTACAACCAACCATGTAAATGCGCTAAATGCCGCTGAATTGTGCACTTTAAAAGGGTGAATTTTAGCCGGGTGTGGTGGTGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGTGGAAGGATCACTTGAGCTCAGGAGGACAACGCTGCGGTGAGCTATGATTGCACCACTACACTCCAGCCTGGGTGGTAGAACAAGACCTCATCTCAAAGATAGATTTATATATATATATAAAAAGTTGAATTTTATGGGATTCTCCATTTTAAAAAGGTGACTGGGAGGGACCTGTGCGCTCTCCTGAGGGGCGAATGGAGCCCTGGGGGAGAACGCCTTGGCACCTTCCCTGGTTGATGAGTTTATTGTCTCAGAACCCCCTTCAAAACCCACAGCCCAGCAGTTTGAGCTTCCAGGAGCCATAAGTGCTTCAGGAAGAAAAAGACTATGATTGTGATTCTCATGTTCCTGCTATGCGTCCCCCTTTGCAGGTGCCCTCCAGGCGGGGGGTGATCAGGCTGCTTGTGTGTTTCAGGTGCTTCTGTACACGTCTCTCCCTGACTTCTGCCATAAGTTTCTACCCGGCTACGTAGGAGGCATCCAGGAGGGGGCCGTGACTCCTGCAGGTAGCCTCCTCCCTTCCACCCTCCCCAGGCTCCCGTTCTCATCCCTTTCTCTCAGGGGCCAGTCCTCCCCAGCGCTGCTTTGTCCCTAAGACTTGTCACAGGATAGAAATCCATTTTGCTTGGATTTTTCACAGCACCAGGCCTCAAAACCATTGAGGGCAGCTGGGGCCATCCCACACCCAGGTTAGAAATCACTTTCCTGGGTAAGGAGGGAATGGATGGCCCAGCTCCTTCCCAGCCCCATAGCAGGGGATGCACTCGGCCCATGAAGCTTCCTGCAGAGACCACCATGCAGAGACCACCATTCCTCGGGGCTGTCCGTGGGAGACCTTGTCTGTTCATTCCTTGCCATCATTGAGAACCCACGAGGAGCCTGGCTTTGTGCCTCTCACGTGGGTGCAGACTGGAACCGCATCCCAACTCTGCCCCCAGAAGCTCCCTGTTTTGAGGGGTGGATGGGCTGAGGTGCTCCCCAACAATTACAGAGGGGGCCAGGCATACCACAGGGGCATCCTCACTTGCTTCTGCCCCTCAGCCCTGACCTCCCTATCAGACTGCACACCTGTCACTCAGCCTATGGCCAGTTAACGAGATGCAGAACCAAAGGATGGACTCAGCCTCCCCTCCCTCTTCCTAGGAGCAGGTAGTTCCTTGGCCAAGGGTATAGGGGCCTCAGAGATGGTTCCTGGGGCCCCAGATGAGGGTCCGCAGCAGCAGAGGCCCAGAAAGTGACCAGGGCCCCCGCCAGGCATGCTTCAGCCCAGCCAAGCTCCTCACTGCGGGTTGGGAAAGCGCCTTCATTTCTGAATCCTTCATCTGCAGGGGTTGTGAACAAGTATCAGATCAATGGCCTGCAAGCCTGGCTCCTCACGCACCTGCTCTGGTTTGCAAACGCTCATCTCCTGTCCTGGTTCTCGCCCACCATCATCTTCGACAACTGGATCCCACTGCTGTGGTGCGCCAACATCCTTGGCTATGCCGTCTCCACCTTCGCCATGGTCAAGGGCTACTTCTTCCCCACCAGCGCCAGAGACTGGTATGTTCTTAGCAGCGGGTCCAGCCTGATGTAGAAAGTGCAAACTTCACCCCTGGCCTTTCTTGCTGCCTGGGGCAGGTGGTTGTAAAGCCCTGAGCACTGAGAATCCGTGGAAGAGGAGGAGGGGGATGGAACTTGCTTCACCCTGGGGAACATCCTTTCTGAATGTTTGGTGGCTTCTCCAGCCTTGGCAAGAATGCAGCTGAAGATGGCCAGGTCAGCTGTGGTGGCCAAGTCATTGCCTTTAGGGCTGGCGTGGGGGTAAGGAAGCCAGGAAAAACTTCTGGCTTGGGGCACAGGCAGCCCATTGCCTCTTTCTTTGGATAAGCTGGTGAGGCCCAAAACAACCTTAGTGAAGAGTCTTATTGTCCCTGTGGCTTTAATTAACAGCTTCCCAGGAGAGCCCTGCTGGCTTGTACCCATTCCCATGGCTGGACAGTGGTGAGCCACTCATCTCTGTCCACTCATCCATTCACCTGCCCATCTCCCCACCCACCCATCCACCCCCCTACCCATTCATCTACCTACTCACCCATCATCCACCTACCCATTGCCCCATCCCATTCACCCACCCACCAATGCATCATCCATCCACCTATCCATCACCCACATCCACCCACCCATCATCCATCCATCTACCCTCCCATCACCCATTCATCCATCTGCCCATCCACCTACCCACCCACCTACACATCTAGCCACACACCCATCCACCTGCCCATCTCCCCATCCTTCCACCTACCCACCCACCCATCCATCATCCATCTCATCCACCTGCCCATCCACCCTCCACCCCGTCTGTCTACCCACCCGTCATCTATTTGTCCATCCACCTATCCACCTACCCACCCACCTACACATCTAGCCACCCACCCATCCACCTGCCCGTCATCCATCCATTTACCCATCCATCCACTCTATCAGGGCCTGTAATGGCATGTGCCGAGGGGAAGGAATGCATCATCTCATCCAGGTCAACCTCCTGCCTGAGCAATGTCCGCAGCTCCTGACCGGCCTCCCTTACCCTCTCAGGCCCTCCTAGCCTGCTCCCTCTGGCTTCCTGGGTGACACTTCTGAACACACCTGATCCCTGCCACCCTGCACCCCAGCTCAACCCTGCCTATCATATATCCATCCACCTGCTCCTCTCCCCATCCCATTCATCCATCCTTCCACCCACTCACCCTGTTATCTATCCATCCATCCATCATAAACCAATGTTTGGGGGGTTCTCTTGTGGACAGTTGTAGGCAGTGGGACTTACAGTTCAGTTTGGGGGATCCAAAAAACCCCAGTGTGGTTTACACCTAGGCTCTTGGGAAATGTTTCTGGAGGATGACACTTTGTAGCTTGTGTGTTATCAGATAACGAGGCTGGCCTTCAATGGCTCCTGGAAATCATCCTCGCTACCTTATAATCATGTAGACTTTGTGTGTTTTGCTTCTTTCTACTTACCCTACCTGAGGGAACTGGACATGAAAATAGGATTTTCTAGTTAACACAGAAATTGTTGTGTGTCCTCAGCCAGCTAGACCTAGTCAGGGTCTCCACAGGGGTTATCTCGGCTGATGCTCTGGCCCTCCGGGGATTGGGGGATTCAGGTAACTGGTCAAAGAACTTGTCCTGCACATGCTGGAAGCCGGGCCCAGGGTGCGTTTGTCATTCTCTACGTTGGCGTGATTTATAATGTCACTCACCCATGAGGGCCCACGTGCCCTGCGTCGGCTTCAAACCGTGTGCTTGGGCCCCAGAACGTAATCTCAGTGCAATCAAGCCAGTTCTTCAGCTCACCTGTGCCATGCGTCAAGGGCATCTGGAGAAGGGTAGAGAGAAACCCAGGTACCAGCCCAGGGCCGGTCTCCCACCCTTCCCGGGTGCAGAGCAGGTGCCCCTGGGCTTCTGCCTAAGGAAGTCTCTGCTGAGCAGCAGCTGAATGCAAAGCAAAGTGAATGAGGGCGCCAGGAACCAGCCGACAAGCATTCCAGCCGTGGGGGTCCCAGCGGCTCATGGCCAGCTTCTGCCTGCGCCGTCTCACGTTACCCTTTAGGACCCTGGGCCAGTGCTGGGCTCTCGCTAAGTAAGGTGGCTTCATCTTGTGAGATATGCTCATCCACTAAATGTATCTTTTATTTATATTTTTAAGCAAATTCACAGGCAATTTCTTTTACAACTACATGATGGGCATCGAGTTTAACCCTCGGATCGGGAAGTGGTTTGACTTCAAGCTGTTCTTCAATGGGCGCCCCGGGATCGTCGCCTGGACCCTCATCAACCTGTCCTTCGCAGCGAAGCAGCGGGAGCTCCACAGCCATGTGACCAATGCCATGGTCCTGGTCAACGTCCTGCAGGTGCCTGTCATGGCTGGAGAGGGTGAAACGCCGATGCCGGCAGGCTCTGGGGGAACCCGCAAGCCAGAGCGTATTCCCATGACCTTAATCTACTGCTTGTAAAAGAGAGTCAGCTGCCCTCCCCAGGTGTCACCAGGAAGCAGCCGGCGAGCACTTGGTGAAGGAAGCCATCCTTGGGTGCCTGTCTCTGCCAGCCCTGGGAGGGGAGGAGGCAGGTTCTACGCAGCCAGGCGTGGTCCAGGAAGGTCTCCCTTGGGGATTACACCTGGGTAGAATCTGGGGGTGTGTGGGAGTTAACCTGGTAGAGTGGAGGCAAGAGTGCATGCTCCAGGAACCCCCTGTAGGGAGAGAGGGTGGCAAGTCTGGGACACTCAGAAACATCCCGCATCCTGACCAGAGAGCGTTCAGGAGCTCAGAGCCAGGTGAGGCTGGAGGCCTCATGGAAGTCTTCCTCTTTATCTTAAAAGCAGCAAGACCCAGAAAGTGTGTGCTGAGCTGGGGTGCAGGGTGGCAGCGATCAGGTGCATTCGGAAGCGTCACCCAGGGAGCCAGCGGGAGCTGGCTAGGAGAACCCGAGAGGGTGAGGGAGGCCTGTCAGGAGCTGTGGACGTTGCTCGGGCAGGAGGTTGACCTGGATGGGATGAATGTATCCCTTCCCCTTGGCACGCGCCATTGCAAGCCCTGAGAACCTGGGCTGGGAGAGATGCCAGGGCCATGGGCTCGGGGTGGTTCTGAGGACAAGGAAGCCCTTAGCCCTGCCCATGACCCAGGCAGGAACAGCCCCAGCCGCAGGGAAGGAACAGCCCCAGCATTGAGGAAGTTGCTGAGCAGCTCCCGAGCACCCCCTGCTGCATCTGCGTGGAGTGTGATTTCCCCGAGGTCCATGGGGGCCCCAGGAGGGCCGGGGGTGGTCAGCGGCTGCTTCTGTCTTGCAGGCCATCTACGTGATTGACTTCTTCTGGAACGAAACCTGGTACCTGAAGACCATTGACATCTGCCATGACCACTTCGGGTGGTACCTGGGCTGGGGCGACTGTGTCTGGCTGCCTTATCTTTACACGCTGCAGGTGAGGAGGTGGGCAGAGCTGGCCCAGCGGGGCATTTGGCAGACACATGCTAAGCTTTCTCCTTGCAGAAGCGTCTGTCCTTGGGGGCACCAAAGCTGCCCCCTGTTTCTAGGAAGAAGGGAAGGCCTCGTGTATTAGCCAGCTCAGCCAGCTTGGGCCAGCAGCCAGGGAGGTGGCCTTGAGTATGTCCCTAACATCTGCAAAGTAGGGCAGATGCCGGCTCAGGGCTGGATGGGGCAGTGGAGGTGGAGGTGGGTCAGTGCGGGCACTGGCAGGAGGGGTCCTCTTCATTCCTGCCTCCTAGGATGTGCTGGGCACTGGGGCAGGGCTGCCCTGGGAGTTCCAGGACAGTAGGGGATAGCAAGTGGCCTTGTCATTGGCATCAAGCCCCCCACTCCCCTCCCAGCTCAACGAGAGCAGCCCTGCTCTGATTTGGGGAGAGTGCTGGGCTCCCAGGTAAGGTGGCTGCTTGACCAGATGCCACCTGCCCATTTCAAGAGCAACGAGCCCCCTGGGGACAGAAATAACTCACCCCAGGGCACTTGCTTAGCAGAACGGTGGGGTGGCCTGCCCCAAGAGGCTGTGCCCAAGTGGAGAGAACCAACGTGGAGAGGCTGTCACCTATTCAGGATGTGACAGGCCCGGCATCACCTGTGACAGCCAGTCCTGTGGGATGGAGGTGCGGGTGTCCTGGAAAACCAGGATTCCCACAGCAGAGGGGGCCAGTACCAGGTGGAGGGTGCAGAGCCCCAGCTGGCCCCATGCTCACACCAGGTCCTTGGAGCCCCCCGCATGGCCCACCCGGCCCCATTTCTCCACCTGGCTGGCTGCAGGTCTGCTGGTTCCCTGGTTTTATAAACTCCATTTTCCAAGGATGTGAAAACGTAGCAATAGGTCCCACTATATAATAGCTCTTACTTGCTTTAGCCTCTGTGTGTGTCTCGAGATGTACATTTTTTATACTATATATTAGGTTTCTCCCAAGAAGCAGAATCAATAGAGGGGTGGAGGGTATACGTGTAAGAAAGAGATGTATTTTTCAACTCATGTGATTGAAGAGTGACAAGTCCAAGATCTTCAGGGCAGCCTGGAGCCCCAGGGAAGAGTTGATGCTGTGCTTAAATAGAAGGTCACTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACACAGGCTAGAGTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCATGCCACCACGCCCAGCTAATTTTTGTACTTTTAGTAGAGATGGGGTTTCACCATGTTAGTCAGGCTGGTCTCAAACTCCTGATCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCATGGCCAGAAGGCCACTTTTTAGCAGATTCCCTCTTCTTTGGGGAAGGTGGGTCTTCTGTCTCTTAAAGCTGTCAACTGATTGGATGAGGCCCACCCCCATTGTGAAGGGTCATCCACTCTGCCTGGTTGACTGATTAACATATGAACCTCATCTGAAAAATGCCTTTACAACTAGTGTTTGACCAAATATCTGGGAACAATGGCCTGGCCAAGTGGACACGTTAAATTGACCATCACAATATTAAATTCAGATTATATTTTTAATACTGTTACATATTTGATGTTTATGCTATATGTCATATATATAGGGGGTATATATACACACACACATACACACACAGACAGGTAGAAGGCAGGTAGAGTTACTCATTTAATGACCACAACAGCCCTCAAGGTTGGTGCTTTTATTCACAGAAGAGAACACGGAGGCAAGGCGTGTGTCAGAGGCAGAGCTGGGGTTTGACCCCAGGCCGCTGGGCCCCCGAGCCCACACTCCTGTCCTCTCCCTGGGCAAAGCACCGCTTGACCCCTTCCCCCTCGCCCCCCAGGGTCTGTACTTGGTGTACCACCCCGTGCAGCTGTCCACCCCGCACGCCGTGGGCGTCCTGCTGCTGGGCCTGGTGGGCTACTACATCTTCCGGGTGGCCAACCACCAGAAGGACCTGTTCCGCCGCACGGATGGGCGCTGCCTCATCTGGGGCAGGAAGCCCAAGGTCATCGAGTGCTCCTACACATCCGCCGATGGGCAGAGGCACCACAGCAAGCTGCTGGTGTCGGGCTTCTGGGGCGTGGCCCGCCACTTCAACTACGTCGGCGACCTGATGGGCAGCCTGGCCTACTGCCTGGCCTGTGGCGGCGGCCACCTGCTGCCCTACTTCTACATCATCTACATGGCCATCCTGCTGACCCACCGCTGCCTCCGGGACGAGCACCGCTGCGCCAGCAAGTACGGCCGGGACTGGGAGCGCTACACCGCCGCAGTGCCTTACCGCCTGCTGCCTGGAATCTTCTAAGGGCACGCCCTAGGGAGAAGCCCTGTGGGGCTGTCAAGAGCGTGTTCTGCCAGGTCCATGGGGGCTGGCATCCCAGCTCCAACTCGAGGAGCCTCAGTTTCCTCATCTGTAAACTGGAGAGAGCCCAGCACTTGGCAGGTGTCCAGTACCTAATCACGCTCTGTTCCTTGCTTTTGCCTTCAAGGGAATTCCGAGTGTCCAGCACTGCCGTATTGCCAGCACAGACGGATTTTCTCTAATCAGTGTCCCTGGGGCAGGAGGATGACCCAGTCACCTTTACTAGTCCTTTGGAGACAATTTACCTGTATTAGGAGCCCAGGCCACGCTACACTCTGCCCACACTGGTGAGCAGGAGGTCTTCCCACGCCCTGTCATTAGGCTGCATTTACTCTTGCTAAATAAAAGTGGGAGTGGGGCGTGCGCGTTATCCATGTATTGCCTTTCAGCTCTAGATCCCCCTCCCCTGCCTGCTCTGCAGTCGTGGGTGGGGCCCGTGCGCCGTTTCTCCTTGGTAGCGTGCACGGTGTTGAACTGGGACACTGGGGAGAAAGGGGCTTTCATGTCGTTTCCTTCCTGCTCCTGCTGCACAGCTGCCAGGAGTGCTCTGCCTGGAGTCTGCAGACCTCAGAGAGGTCCCAGCACCGGCTGTGGCCTTTCAGGTGTAGGCAGGTGGGCTCTGCTTCCCGATTCCCTGTGAGCGCCCACCCTCTCGAAAGAATTTTCTGCTTGCCCTATGACTGTGCAGACTCTGGCTCGAGCAACCCGGGGAACTTCACCCTCAGGGGCCTCCCACACCTTCTCCAGCGAGGAGGTCTCAGTCCCAGCCTCGGGAGGGCACCTCCTTTTCTGTGCTTTCTTCCCTGAGGCATTCTTCCTCATCCCTAGGGTGTTGTGTAGAACTCTTTTTAAACTCTATGCTCCGAGTAGAGTTCATCTTTATATTAAACTTCCCCTGTTCAAATAAGTGGCTGTGTGGTTTCTGACTGGTGAATGGGCCTGACTCGTGAATGGGCCTGACTGCAGGTCTGACTGGTATACGTGGGCTCTGTTTCTGGTATGAGAAGGGATGTCTGAGAGAGATGCTTGGGTCTCGGCGTCAAAGCATTGGGTGCCCGTGGGTGCGTGGCGCCACCCTGCCCCTCTCCCTCCCATGTCAGCCCTTTGCTGGGGCTGTTTTTGGGTTGAATGTGGAGAGTATTCCATTCCCCCCCAAGGAGATGAAACCAGGCTTGGCCACCTGCCCCCGGCAAGTGAATGGAGAAGCCAGAAAGAGTGCCAGGTTTGTCTTGCACCTGGAGAAACAAGAGTTTCACACAGGCAGCCCAGTGCCCATGCCAGGGCAGGGGGCCAAGCTCAGAGTGGCTTCATTGCTTCACATGAGAACTGGTCCCACAGCCAGGCCGCCTCCCAGACAGCCTGGAGGGTATCGGAACTGTGACCCGCCCAGGCTGACTGCTGAGCCCTAGTGTTCGTGCACTGGTGCCCCACCACTACCTGTTTGAGGATATGGGCCTGAGGGGTCCCGTGCATCTGTGCTGGACACACACCACAAGAGTGATTCAAATGCCGGGGAGACGGGAGCACACTGCCCTGCATGGCTCTGAGCGGAGTGGACCCTGCCTTTTCTTCCCAGACATTGCGTAAATTCAGTTCACAGAGGCTGGGGTGTGGTCACTGTGAGCTCAGATCCGGGCCTCCCTGCCTGCGTTGGAATCCTGGCCCCAGCATTTAAGAGCTGTATGACCTTCAGGGGACCTACCCTCTCAGTGTCTCAGCTTCCTCTTTTGAAAGATGAGGGTCATTATTATCTTCCTGCCTTGATGTGAGAAGGGCTTTCCAGGCCAATTTGCTGGGAGAGCTCTTGGTTCAGATGTGGACCTGCCTCTGAATTGGCTGAGGTTAGCTTTTGGTTTGGTTTCTGTTTGAGCAGCTTTGTGCTGGGCTGCAGGTTCCTCTTCCATGCACTGTGTGTTTGTACAATGGGTTCTGCAGGTGCAAGGCTGTGGCCCAGGCTCTGTCCCACCAGACACGTCTGCCCTCACTCATCCCCAGATGGAGCCAGCTTCTCTCTGGGCGAGAACAGGGTGATCCAGGAGCTCAGATTAGACAGTGCCAGCCTCTACCATTCTCCATGTACAGAGAGCATTCTGTTCCCAGTGAAGCCACAGTGCCTGATCCCTGGGAAGCTGGCCTGGCCTTTGCCCCCTTCCAGAATGAAGGACGGCTCGGACCAATTGCCAGGGCCATCTGAACTGTGCTTTACAGGGCATGGCACTGCCCTCTGATAAGGGGCAGGCATCCAGTACCCCAGGACAGGGTCAGGGCAGGAATCCAGTGGGCACATTCAGAGAGGCTATTTTCCCATGAGTAGATTCAATCCTGATACACCCCACCCTCTCCAACCTCAACCTTCGAAAGCGAGGTGAGGCCTTTCTCAGAAACCACCCTGCTTGCTGTTGGCTCCAGCAGATCTGCTTTCTGGTCCACATTTAACAATCAATTGCTCAGCACATATCTCTGTCCTGGGAGGAGCTGCGCAGATTGCAGGCACTGTCTTTGATGGCACAGCTGATTTCTTGGGAAACTGAGGCCTGGGGTTTAAAGCAACTCACCCCAAATGACAGAACTAGCAACTGGTAGAGGCCAAATTTAAACCTAAGGAGGAGAGGCAAAGGGGCAATGTAGGTCACAGAGTACAATGTTTGGGTTAGACAGGAGAATAAGTTTCTGAGATCTGTGGCACAGCATGGTGGGTGACCATAGTTCGGAATGTATTATATATTTCAAAATTGCTAAGAGTAAATTTTCAGTGTTCTCACTATGCCCACAAAAATACACAGATGAAGTTATGGATATGTTAATTAGCTTGATTTACTCATTCTGCAATTTACACATGTATCAAAACATCACATTGTACCCCATAAATATAAACAATTATTGTCAATTGAAAATACCATTAAAAAATATAAATGACCAATGAAGATCTGAAAAGCTGTTCAATTTCCCTAGTAATTAGAGGGAGGAAAGTTAACATCACGTGATCCTTTGGCAAACTTGATCACATTGGCAAACTTTATTGCAGCAGTAACTCCCAGCATCACCAAGGTCAACAAGAAGCCAGTGTTCTCCTAAACAGTACGTAGGAGTTCTGTTCATTCACGTCAAGAAATTTACCCTGAAGAAATCAAGGGAGGAGGAATATGTTTCAATAACAATGTTGGTGCAAGTATGGTAGATAATAAAGTTTTCTGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAATGTGGGCAGATCACTTGAGTTCAGGAGTTTGAAACCATCCAGGGCAACATGGCGAAACCCCATCTCTGTAAAAACAATTAAAAAATTAGTTGGGCATGGTGGCACATGCTTGTAGTCCCAGCTATTCAGGAGGCTGAGGCAGGAGGATCACCTGAGCCTGGGGAGGTTGAGGCTGTAGTGGACCGTGATTGTGCCATTGCACTCCAGCCTGGGCCAACAGAGCAAGACCCTGTCTCAAAAAAAATAAAGTTTTCATATGAAATATATACATAAAAGGATATATACCAAAACATAAACATTAATGCTATTCATAGCTGCATAGCGGAGGTAATAGATAGTGGTTTTTTTCTGTATTTTTGATAAATGTTATTTTTCAGCAACACTTCTGCAGGATTATAGTAGTGGTGAGGAAGGCTGCTTGCACCTGGACAGATACAATGCATTTGTTTTTAATAAACTAGACCTTCCTGCCCTAAGCAGGCCAAGGAGGAGGAGGAGGACTTCTGGCCAGGAGGGGGGTTTCCACGCAGGCACTGGTGCCACCGAGGGCCGACTGGGCTTGGTTTCACCACGTTGCCTGCAGGGAGGGCTGTTTCAGGAGCAGGAGTCAGCCCTTCTTGTCTGGAGTACTGTCAGAGGTGGGCGTCAGTGATAGCGACAGGAGGCAGCCAAATGCCCAGCAGACAGAGGTGGATCCCCGGTGAAGCCCCACCTCCAAGCCAAAGACAGTTTAAAGCCTGAAAGCCAAGCTATCCTTGGACTGGACTGACAACTTGTCTTGCTGTTTGGTGCACTTCCCTCTGATGGATCCCCACCCTTCACCTATTTTACATATACCCAACCTTTCCTAATTGGTTTCCTACACTGTTGTGTCCACCTTTGAGTGGCATCTTTGCTTTAACCTTTTGTTTGTTTGTTTTGGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCTGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCACCACCATACCCGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCTAACCTCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCTAGTTTTAACCTTTTACTGCATACTCACAAGCCAATCAGCATGCACTCCCCATCCTGTACCTATAAAGACTCCAGACTCATTCAGTAGAGGGGAGACGGCCTGACTTTGGGGAAGATGACCTGCCCTTCCTGGCCCCTCTCTAGCTCCCCTCTCCACTTAGAGCTGTTTTGGTTGCTCAGTAAAATTCTCGGCCTTCACCATCCTTCAAGTGTCCATATGACTTCATTCTTTTTGGATGCTGGGCAAGAGTGGGACCCAGCTAGTGTGAGTACCCAGAAAGGCTGTCACACTAGCCCTTTGCCCTTGCCAGTGGAGGGCAGCCACCCCACATGACAAGGCAGGGGGACAACTGAGCTGCTAACACACCACCACCCACAAATGGCAGAACTAAAGGAGCACTGTAACACTGCCTCTGGGGCTTTGGGGTCACAGGCACCCTCACCTGGGTGCTGCAACACGCCTAGTCTGGCCACGGGTCCTGCATGGAGCTTGCTCCTGTGTCTGCACTTGGAATGGCCGGCCGGATCCCACACTCACATGCTCACATGCTCCCTCCCACAAGGGGTTGAGCACAGTGAGCTGAGTAGACGGGGCGCCCCTGCTGTGAGTCCCGTGAAAGGACCAAGAAAAACCCTGCATTATCAGGAGAGGGAACGTCAGGCCACAGCCCGGCCAGATTTTCTGGTCAAGAGGCCTCATTGAGGAGAACATTCCATGCAGACTTGAGATCTAAGTCCCCTCTGTGTGTTTATTTCATCAGGATGGGCAGATTATTCTCCCTGAGTGCCTCCTCAGCTCACAGATCCACTCTTGCCCCTTTCCCAAACCTTGGTCTCCAAATCTGTTAGGAAATCTGGATGTTACCTGGGAAGACCAAGACCGCAGTGACTGGGAGCTGGGGACGGGATGGGTCTGGCTTTTGGAAACTCAATGCCTCAAATTCAACAATGAGCCACAGACGTGGACCAGCTCTTTGTTGTTCCAGGAAGTGGTCAGGGGTGGGGGTTTGCACAGGGTGAGTGTGGTCACCTGGACACACAGGGAAGCTGCAAGATGGCTGTTAGCAAGAGGCAAGTACCAGGCAAGTCCACCTGGCTCACAGCTTTAAACACCTCCACGGCTTGGTGACTCCAAGGTTTCATCTCCAGCCATGCCTTTGTCCTGAACGCCGCTCATGAGTCCACATGCTCCCTCTACACCTCACTCAGCATCTGAAAGGTTACTCGACTTCACCCCCTCAATCAGTACTGACCTTTTCCCATAAATGTCAGTTGCTCTAACCGAAAACCAGGTATCATCCCTGACTCCCCTCCCTCACGCCACGTTCCATCAGAGGGCAAGCCTGTGGCTGTGCCCATGAAATGTCCAGGATCTGACCGCTTTCCATCTACCGGGTGCCCCCGTCCCAGGCTCTGTCCTCTCTTAGCCTCAGCGCATGTCTCCCTGCCTCCTGCCCCCGCCCACAGTCTGTTCTCGGCTCAACAGCCAGACTATCCCATCAAAATGTGAGTCACATGCTGTCACTCCACTGCTCAGAACTTTCCAAGGTCTTCTCATGTTGCTCAGAATAAAAGCCAGGGTCGTTCTGAGGGCCTCAGCCGCCCTGTGGACTGTCAGACCTCTCTTGCTGCAGCCTCCCATATTGACACAGCAATAGCCATGCCCACCACCTCCCTGGGCCTCTGGCACTGCTCCACCTCAGTCAAAGCCCAGTTAGAACTACTGATGCAAATCCCCACAGCCAGGATCATCAAGACATCGGCCGCCAAGCTTTCTGGCCAGGGATTTCAGTTGCAGAACTGTTTGCAACACTTAGCTGCAATGGAAGTGCCAATTCTGGAACTGGTTTCCTTGTTGTTGGCTCACTTCTTCCTACCCCTGAGCACACTTGGAAGGCTACAGACTTAGATAAGTGAGGAGGAGGCGGGAGGCATTTGAATTACATGGTTATTATTTTTTTCTTTAACTGGGAGTGAACTCCACTCTGTCTTGAGAAAGAATTCTTGACTTGCCTTGCAGATGAGAAATGCTGCTGTGGAGGCTGAGTAGAGGCAGGAAGAGCTGCCTTCCCTTTAAGACTTGGAGATGACCCTGGGGAGGGCAGCAAAGGCGTCTGCAGAACCATCTGGGCTGTTTCCCCCTGGACAGGACTGCAGGGAGCTGCAGGGAGCTGCAGGGAGGTTCACCACGGCCCTCTGTACCTTGGAATACACTAAGATCTCCAGGGTGTGGTGGTCCTATGCCCACACATCCCACTGTTAGGAGTGTCCTCACAGTTATATCCTGCCATGTGCGAAATGGCTGCAAGTTCAAGGCTGTGCATTGCAGTGTCCTGTGCAAAAAAACCGTGAAAAGATCGGGAACAAGTTATGCAAATCAAGAGGTGACTGTTTAATTAAGTGCATCCACATGATGGAATGTTATAAAGCTCTCAAAAAGAATAGGACAGTCAACTGATGATGAATCACATTAACTTAATAAGGAAGAAAAACCACTTTATTATATGAAATAGATGGAGAAAAAAGGACACTAATTCATAATAAAAACGCAAAGACATCCATAGAAAACCTACAGCTAACTTCATATTTAATGATGAGATATTGGATTCTCTCATCATAAGATCAAGAACATGGCAAGAATTTTCACTGCCACTTCTTCCAAATTACATTAGAGATCCTA

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