Details for gene: MDM2


This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]


Symbol
MDM2
Name
MDM2 proto-oncogene
Entrez ID
4193
Ensembl ID
ENSG00000135679    (more details)
KEGG ID
hsa:4193    (more details)
OMIM ID
618681
Uniprot ID
Q96DS0  
GO ID
hsa:4193    (more details)
Chromosome
12
Strand
1
Start
68808177
End
68845544
miRNA Interactions
hsa-miR-30c-5p (RPM: 3890.0396) / hsa-miR-15a-5p (RPM: 139.425) / hsa-miR-1277-5p (RPM: 3.0234) / hsa-miR-29b-3p (RPM: 118.8178) / hsa-miR-20a-5p (RPM: 55.9816) / hsa-miR-212-3p (RPM: 7.7608) / hsa-miR-548at-5p (RPM: 0.3546) / hsa-miR-195-5p (RPM: 125.6474) / hsa-miR-29c-3p (RPM: 661.3514) / hsa-miR-3658 (RPM: 0.0008) / hsa-miR-30d-5p (RPM: 9562.1366) / hsa-miR-30a-5p (RPM: 15590.711) / hsa-miR-15b-5p (RPM: 133.5752) / hsa-miR-29a-3p (RPM: 1246.9046) / hsa-miR-30e-5p (RPM: 2305.0396) / hsa-miR-124-3p (RPM: 4110.4386) / hsa-miR-26a-5p (RPM: 45169.4864) / hsa-miR-16-5p (RPM: 2473.4704) / hsa-miR-106b-5p (RPM: 35.4204) / hsa-miR-126-5p (RPM: 3089.0568) / hsa-miR-340-5p (RPM: 285.763) / hsa-miR-424-5p (RPM: 9.04) / hsa-miR-27b-3p (RPM: 22876.2392) / hsa-miR-1290 (RPM: 0.1162) / hsa-miR-26b-5p (RPM: 2999.0356) / hsa-miR-135b-5p (RPM: 25.9152) / hsa-miR-942-5p (RPM: 2.297) / hsa-miR-106a-5p (RPM: 7.9736) / hsa-miR-1297 (RPM: 0.0024) / hsa-miR-30b-5p (RPM: 1466.5144) / hsa-miR-27a-3p (RPM: 980.3062) / hsa-miR-377-3p (RPM: 4.0398) / hsa-miR-541-3p (RPM: 0.7484) / hsa-miR-5582-3p (RPM: 0.0138) / hsa-miR-335-3p (RPM: 837.9252) / hsa-miR-3613-3p (RPM: 0.8106) / hsa-miR-338-3p (RPM: 158.4942) / hsa-miR-450b-5p (RPM: 4.6184) / hsa-miR-19b-3p (RPM: 197.0578) / hsa-miR-19a-3p (RPM: 25.4064) / hsa-miR-381-3p (RPM: 109.8078) / hsa-miR-4326 (RPM: 2.7166) / hsa-miR-497-5p (RPM: 49.4968) / hsa-miR-4697-3p (RPM: 0.084) / hsa-miR-758-3p (RPM: 5.044) / hsa-miR-374a-5p (RPM: 52.6724) / hsa-miR-339-5p (RPM: 44.716) / hsa-miR-107 (RPM: 234.4574) / hsa-miR-103a-2-5p (RPM: 0.387) / hsa-miR-92a-3p (RPM: 16961.15) / hsa-miR-3926 (RPM: 0.0072) / hsa-miR-300 (RPM: 0.0012) / hsa-miR-944 (RPM: 13.3166) / hsa-miR-590-3p (RPM: 4.5954) / hsa-miR-223-3p (RPM: 14.321) / hsa-miR-513a-5p (RPM: 0.3656) / hsa-miR-129-5p (RPM: 135.1492) / hsa-miR-3662 (RPM: 0.0344) / hsa-miR-92b-3p (RPM: 8345.0264) / hsa-miR-205-3p (RPM: 1.669) / hsa-miR-103a-3p (RPM: 2034.8158) / hsa-miR-5006-3p (RPM: 0.4468) / hsa-miR-582-5p (RPM: 8.1398) / hsa-miR-96-5p (RPM: 1417.2834) / hsa-miR-148a-3p (RPM: 10339.6222) / hsa-miR-4738-3p (RPM: 0.3144) / hsa-miR-767-5p (RPM: 20.579) / hsa-let-7b-5p (RPM: 3396.2052) / hsa-miR-579-3p (RPM: 0.0084) / hsa-let-7f-5p (RPM: 17066.6836) / hsa-miR-4504 (RPM: 0.0652) / hsa-miR-129-2-3p (RPM: 79.8688) / hsa-miR-624-5p (RPM: 0.5246) / hsa-miR-654-5p (RPM: 2.4606) / hsa-miR-3127-3p (RPM: 0.1826) / hsa-miR-4705 (RPM: 0.444) / hsa-let-7c-5p (RPM: 4028.6728) / hsa-miR-1301-3p (RPM: 47.2112) / hsa-miR-148b-3p (RPM: 970.7614) / hsa-miR-152-3p (RPM: 242.0024) / hsa-miR-4786-3p (RPM: 0.0288) / hsa-miR-664b-3p (RPM: 4.7274) / hsa-miR-378a-5p (RPM: 22.027) / hsa-miR-361-5p (RPM: 182.4758) / hsa-miR-589-5p (RPM: 54.2348) / hsa-miR-365a-3p (RPM: 22.318) / hsa-miR-1270 (RPM: 4.4328) / hsa-miR-9-5p (RPM: 3525.806) / hsa-miR-452-5p (RPM: 23.696) / hsa-let-7i-5p (RPM: 2025.2084) / hsa-miR-186-5p (RPM: 1645.2832) / hsa-miR-5010-3p (RPM: 1.8422) / hsa-miR-98-5p (RPM: 1660.0964) / hsa-let-7e-5p (RPM: 3790.2074) / hsa-miR-153-3p (RPM: 53.4548) / hsa-let-7g-5p (RPM: 3559.4376) / hsa-miR-519d-3p (RPM: 0.0042) / hsa-miR-877-3p (RPM: 0.509) / hsa-miR-221-3p (RPM: 758.7978) / hsa-miR-365b-3p (RPM: 22.318) / hsa-miR-488-3p (RPM: 11.3394) / hsa-miR-30e-3p (RPM: 538.304) / hsa-miR-30a-3p (RPM: 889.1386) / hsa-let-7a-5p (RPM: 32160.4734) / hsa-miR-32-5p (RPM: 14.5562) / hsa-miR-484 (RPM: 434.5276) / hsa-miR-542-3p (RPM: 2.7294) / hsa-miR-3619-5p (RPM: 0.0804) / hsa-miR-30d-3p (RPM: 57.136) / hsa-let-7f-1-3p (RPM: 9.5776) / hsa-miR-3190-5p (RPM: 0.0008) / hsa-let-7b-3p (RPM: 92.0818) / hsa-miR-7-5p (RPM: 19.3682) / hsa-miR-1305 (RPM: 0.128) / hsa-miR-5580-3p (RPM: 0.0162) / hsa-miR-577 (RPM: 1.8138) / hsa-miR-664a-3p (RPM: 65.4214) / hsa-miR-610 (RPM: 0.032) / hsa-miR-548s (RPM: 0.1718) / hsa-let-7a-3p (RPM: 33.7298) / hsa-miR-876-5p (RPM: 0.4744) / hsa-miR-432-5p (RPM: 29.044) / hsa-miR-127-5p (RPM: 9.9124) / hsa-miR-19b-1-5p (RPM: 0.1482) / hsa-miR-513b-5p (RPM: 0.2552) / hsa-miR-374b-5p (RPM: 72.7188) / hsa-miR-410-3p (RPM: 194.4724) / hsa-miR-10a-3p (RPM: 0.0878) / hsa-miR-4729 (RPM: 0.049) / hsa-miR-214-3p (RPM: 21.2784) / hsa-miR-520a-3p (RPM: 0.0858) / hsa-miR-545-5p (RPM: 0.3484) / hsa-miR-1296-5p (RPM: 36.5114) / hsa-miR-5680 (RPM: 0.2512) / hsa-miR-1225-3p (RPM: 0.001) / hsa-miR-204-5p (RPM: 265062.0076) / hsa-miR-143-3p (RPM: 93089.5152) / hsa-miR-548ah-5p (RPM: 1.0636) / hsa-miR-656-3p (RPM: 3.3332) / hsa-miR-5696 (RPM: 0.3778) / hsa-miR-101-5p (RPM: 15.2398) / hsa-miR-21-5p (RPM: 5494.851) / hsa-miR-4728-5p (RPM: 0.1204) / hsa-miR-105-5p (RPM: 5.4344) / hsa-miR-500a-5p (RPM: 1.3064) / hsa-miR-203a-3p (RPM: 1346.5646) / hsa-miR-766-3p (RPM: 5.2956) / hsa-miR-142-5p (RPM: 245.4844) / hsa-let-7d-5p (RPM: 1078.3154) / hsa-miR-580-3p (RPM: 0.1496) / hsa-miR-145-5p (RPM: 548.8656) / hsa-miR-548l (RPM: 0.078) / hsa-miR-4635 (RPM: 0.0156) / hsa-miR-362-3p (RPM: 1.4456) / hsa-miR-4511 (RPM: 0.216) / hsa-miR-18b-5p (RPM: 0.3398) / hsa-miR-5192 (RPM: 0.0024) / hsa-miR-18a-5p (RPM: 3.6074) / hsa-miR-1252-5p (RPM: 0.4902) / hsa-miR-193a-3p (RPM: 13.6064) / hsa-miR-589-3p (RPM: 1.3938) / hsa-miR-185-5p (RPM: 29.191) / hsa-miR-181b-3p (RPM: 2.493) / hsa-miR-1-3p (RPM: 26.3428) / hsa-miR-873-5p (RPM: 18.2502) / hsa-miR-4711-3p (RPM: 0.0032) / hsa-miR-4742-5p (RPM: 0.1632) / hsa-miR-1185-2-3p (RPM: 0.191) / hsa-miR-193b-3p (RPM: 184.968) / hsa-miR-1343-3p (RPM: 3.6608) / hsa-miR-219a-5p (RPM: 0.9656) / hsa-miR-605-5p (RPM: 0.3176) / hsa-miR-1229-3p (RPM: 1.3764) / hsa-miR-1185-1-3p (RPM: 1.5496) / hsa-miR-1233-3p (RPM: 0.4168) / hsa-miR-940 (RPM: 4.614) / hsa-miR-4470 (RPM: 0.0068) / hsa-miR-378c (RPM: 29.1044) / hsa-miR-4786-5p (RPM: 0.6678) / hsa-miR-4521 (RPM: 0.5154) / hsa-miR-142-3p (RPM: 8.3404) / hsa-miR-378a-3p (RPM: 1540.7796) / hsa-miR-338-5p (RPM: 16.892) / hsa-miR-30b-3p (RPM: 13.9872) / hsa-let-7f-2-3p (RPM: 13.1322) / hsa-miR-33a-5p (RPM: 5.9422) / hsa-miR-671-5p (RPM: 10.1036) / hsa-miR-23b-3p (RPM: 2125.0486) / hsa-miR-342-5p (RPM: 28.1628) / hsa-miR-628-5p (RPM: 28.0514) / hsa-miR-496 (RPM: 1.0276) / hsa-miR-4797-5p (RPM: 0.017) / hsa-miR-23a-3p (RPM: 613.2568) / hsa-miR-130b-5p (RPM: 60.0122) / hsa-miR-376a-5p (RPM: 4.9822) / hsa-miR-2113 (RPM: 0.0968) / hsa-miR-1287-5p (RPM: 8.4442) / hsa-miR-149-3p (RPM: 0.3876) / hsa-miR-3620-3p (RPM: 0.8762) / hsa-miR-19a-5p (RPM: 0.3142) / hsa-miR-1260a (RPM: 220.2948) / hsa-miR-192-3p (RPM: 0.4144) / hsa-miR-508-5p (RPM: 0.6) / hsa-miR-378d (RPM: 8.7748) / hsa-miR-196b-5p (RPM: 0.2478) / hsa-miR-3179 (RPM: 0.0296) / hsa-miR-660-3p (RPM: 0.609) / hsa-miR-499a-5p (RPM: 5.597) / hsa-miR-224-3p (RPM: 2.0554) / hsa-miR-641 (RPM: 12.2284) / hsa-miR-25-3p (RPM: 1063.0626) / hsa-miR-3929 (RPM: 0.0406) / hsa-miR-708-3p (RPM: 46.9334) / hsa-miR-5682 (RPM: 0.013) / hsa-miR-4726-3p (RPM: 0.0088) / hsa-miR-421 (RPM: 76.7678) / hsa-miR-873-3p (RPM: 8.911) / hsa-miR-556-3p (RPM: 0.5384) / hsa-miR-3617-5p (RPM: 1.88) / hsa-miR-561-3p (RPM: 0.023) / hsa-miR-556-5p (RPM: 0.386) / hsa-miR-522-3p (RPM: 0.0056) / hsa-miR-4683 (RPM: 0.0052) / hsa-miR-224-5p (RPM: 33.3102) / hsa-miR-222-3p (RPM: 1699.0194) / hsa-miR-625-5p (RPM: 10.5462) / hsa-miR-526b-5p (RPM: 0.2456) / hsa-miR-29b-2-5p (RPM: 5.083) / hsa-miR-505-3p (RPM: 14.5424) / hsa-miR-744-3p (RPM: 3.4814) / hsa-miR-548b-3p (RPM: 0.1786) / hsa-miR-374a-3p (RPM: 56.346) / hsa-miR-3117-5p (RPM: 0.018) / hsa-miR-5009-5p (RPM: 0.0384) / hsa-miR-651-5p (RPM: 2.417) / hsa-miR-17-3p (RPM: 13.6088) / hsa-miR-545-3p (RPM: 0.0276) / hsa-miR-376c-3p (RPM: 10.6544) / hsa-miR-1271-5p (RPM: 29.1658) / hsa-miR-9-3p (RPM: 123.624) / hsa-miR-146b-5p (RPM: 934.8654) / hsa-miR-342-3p (RPM: 685.7862) / hsa-miR-196a-5p (RPM: 0.311) / hsa-miR-3685 (RPM: 0.0826) / hsa-miR-1278 (RPM: 0.2792) / hsa-miR-146a-5p (RPM: 774.8698) / hsa-miR-330-3p (RPM: 21.3424) / hsa-miR-4306 (RPM: 0.006) / hsa-miR-155-5p (RPM: 106.9134) / hsa-miR-425-5p (RPM: 187.631) / hsa-miR-628-3p (RPM: 10.2162) / hsa-miR-93-5p (RPM: 357.1536) / hsa-miR-192-5p (RPM: 3146.8498) / hsa-miR-532-3p (RPM: 21.9476) / hsa-miR-3614-5p (RPM: 0.263) / hsa-miR-483-3p (RPM: 2.3898) / hsa-miR-629-5p (RPM: 7.1172) / hsa-miR-17-5p (RPM: 83.6404) / hsa-miR-431-3p (RPM: 4.2164) / hsa-miR-20b-5p (RPM: 24.4036) / hsa-miR-16-1-3p (RPM: 0.0972) / hsa-miR-181a-2-3p (RPM: 1451.5764) / hsa-miR-504-5p (RPM: 27.4444) / hsa-miR-3125 (RPM: 1.2126) / hsa-miR-4644 (RPM: 0.0058) / hsa-miR-363-3p (RPM: 298.497) / hsa-miR-3916 (RPM: 0.1044) / hsa-miR-188-3p (RPM: 0.727) / hsa-miR-335-5p (RPM: 265.7294) / hsa-miR-4685-3p (RPM: 0.7634) / hsa-miR-34a-3p (RPM: 0.9902) / hsa-miR-27a-5p (RPM: 7.3838) / hsa-miR-140-5p (RPM: 21.3322) / hsa-miR-1255b-5p (RPM: 0.0196) / hsa-miR-1322 (RPM: 0.1004) / hsa-miR-550a-3p (RPM: 2.5866) / hsa-miR-15a-3p (RPM: 0.0624) / hsa-miR-3692-3p (RPM: 0.0008) / hsa-miR-186-3p (RPM: 0.0884) / hsa-miR-296-3p (RPM: 8.5012) / hsa-miR-4433a-3p (RPM: 0.0012) / hsa-miR-660-5p (RPM: 107.579) / hsa-miR-616-3p (RPM: 0.3382) / hsa-miR-3199 (RPM: 0.1412) / hsa-miR-1228-5p (RPM: 0.2916) / hsa-miR-935 (RPM: 3.3072) / hsa-miR-3609 (RPM: 6.639) / hsa-miR-374b-3p (RPM: 5.4276) / hsa-miR-615-5p (RPM: 0.0058) / hsa-miR-1260b (RPM: 243.165) / hsa-miR-1255a (RPM: 0.3384) / hsa-miR-3145-5p (RPM: 0.2498) / hsa-miR-181c-3p (RPM: 135.7028) / hsa-miR-5008-3p (RPM: 0.203) / hsa-miR-208a-3p (RPM: 0.0064) / hsa-miR-500a-3p (RPM: 426.0306) / hsa-miR-208b-3p (RPM: 0.919) / hsa-miR-487b-3p (RPM: 27.5062) / hsa-miR-4649-5p (RPM: 0.0842) / hsa-miR-218-5p (RPM: 36.775) / hsa-miR-10b-5p (RPM: 14052.6542) / hsa-miR-10a-5p (RPM: 408.7974) / hsa-miR-210-3p (RPM: 361.0562) / hsa-miR-331-5p (RPM: 4.2262) / hsa-miR-423-3p (RPM: 1928.5158) / hsa-miR-383-5p (RPM: 1.9172) / hsa-miR-181a-3p (RPM: 391.4974) / hsa-miR-200c-5p (RPM: 0.9464) / hsa-miR-98-3p (RPM: 19.7302) / hsa-miR-6873-3p (RPM: 0.12) / hsa-miR-7110-3p (RPM: 0.0382) / hsa-miR-95-5p (RPM: 0.9772) / hsa-miR-6785-5p (RPM: 0.0412) / hsa-miR-6883-5p (RPM: 0.0016) / hsa-miR-6720-5p (RPM: 0.0746) / hsa-miR-6871-3p (RPM: 0.027) / hsa-miR-6508-5p (RPM: 0.0712) / hsa-miR-6849-3p (RPM: 0.0148) / hsa-miR-7106-5p (RPM: 0.007) / hsa-miR-6817-3p (RPM: 0.0036) / hsa-miR-1273h-5p (RPM: 0.1102) / hsa-miR-939-3p (RPM: 0.04) / hsa-miR-6505-5p (RPM: 0.6144) / hsa-miR-6780a-5p (RPM: 0.2598) / hsa-miR-6779-5p (RPM: 0.1952) / hsa-miR-7703 (RPM: 0.3104) / hsa-miR-6879-3p (RPM: 0.0316) / hsa-miR-552-5p (RPM: 0.0208) / hsa-miR-6516-5p (RPM: 0.859) / hsa-miR-6799-5p (RPM: 0.0034) / hsa-miR-7843-3p (RPM: 0.002) / hsa-miR-6758-3p (RPM: 0.0132) / hsa-miR-4433b-3p (RPM: 0.0038) / hsa-miR-6865-3p (RPM: 0.0874) / hsa-miR-6888-5p (RPM: 0.0256) / hsa-miR-6859-5p (RPM: 0.856) / hsa-miR-6729-5p (RPM: 0.0606) / hsa-miR-6808-3p (RPM: 0.0008) / hsa-miR-7850-5p (RPM: 0.0048) / hsa-miR-6500-3p (RPM: 1.2556) / hsa-miR-6864-5p (RPM: 0.1318) / hsa-miR-6089 (RPM: 0.0044) /
Involved Diseases
retinoblastoma /
Involved Pathways
PI3K-Akt signaling pathway / Transcriptional misregulation in cancer / Epstein-Barr virus infection / MicroRNAs in cancer / Endocytosis / FoxO signaling pathway / Cell cycle / p53 signaling pathway / Shigellosis / Thyroid hormone signaling pathway / Pathways in cancer / Proteoglycans in cancer / Bladder cancer / Viral carcinogenesis / Chronic myeloid leukemia / Glioma / Prostate cancer / Melanoma / Ubiquitin mediated proteolysis / Cellular responses to stress / Cellular responses to external stimuli / Generic Transcription Pathway / RNA Polymerase II Transcription / Gene expression (Transcription) / Cell Cycle / Disease / Diseases of signal transduction by growth factor receptors and second messengers / Metabolism of proteins / Post-translational protein modification / Cellular Senescence / Transcriptional Regulation by TP53 / Regulation of TP53 Activity / Regulation of TP53 Activity through Phosphorylation / Regulation of TP53 Degradation / Regulation of TP53 Activity through Methylation / Regulation of TP53 Expression and Degradation / Stabilization of p53 / p53-Dependent G1 DNA Damage Response / p53-Dependent G1/S DNA damage checkpoint / G1/S DNA Damage Checkpoints / Cell Cycle Checkpoints / Signal Transduction / Transmission across Chemical Synapses / Neuronal System / Neurotransmitter receptors and postsynaptic signal transmission / Trafficking of AMPA receptors / Glutamate binding, activation of AMPA receptors and synaptic plasticity / Oxidative Stress Induced Senescence / Oncogene Induced Senescence / SUMOylation / SUMO E3 ligases SUMOylate target proteins / SUMOylation of transcription factors / PIP3 activates AKT signaling / PI3K/AKT Signaling in Cancer / Deubiquitination / Ub-specific processing proteases / Intracellular signaling by second messengers / Transcriptional regulation by RUNX3 / Regulation of RUNX3 expression and activity / AKT phosphorylates targets in the cytosol / SUMOylation of ubiquitinylation proteins / Constitutive Signaling by AKT1 E17K in Cancer /
Sequence
GGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGTACTGGCCCGGCAGCGAGCGGTCACTTTTGGGTCTGGGCTCTGACGGTGTCCCCTCTATCGCTGGTTCCCAGCCTCTGCCCGTTCGCAGCCTTTGTGCGGTTCGTGGCTGGGGGCTCGGGGCGCGGGGCGCGGGGCATGGGGCACGTGGCTTTGCGGAGGTTTTGTTGGACTGGGGCTAGGCAGTCGCCGCCAGGGAGGAGGGCGGGATTTCGGACGGCTCTCGCGGCGGTGGGGGTGGGGGTGGTTCGGAGGTCTCCGCGGGAGTTCAGGGTAAAGGTCACGGGGGCCGGGGGCTGCGGGGCCGCTTCGGCGCGGGAGGTCCGGATGATCGCAGGTGCCTGTCGGGTCACTAGTGTGAACGCTGCGCGTAGTCTGGGCGGGATTGGGCCGGTTCAGTGGGCAGGTTGACTCAGCTTTTCCTCTTGAGCTGGTCAAGTTCAGACACGTTCCGAAACTGCAGTAAAAGGAGTTAAGTCCTGACTTGTCTCCAGCTGGGGCTATTTAAACCATGCATTTTCCCAGCTGTGTTCAGTGGCGATTGGAGGGTAGACCTGTGGGCACGGACGCACGCCACTTTTTCTCTGCTGATCCAGGTAAGCACCGACTTGCTTGTAGCTTTAGTTTTAACTGTTGTTTATGTTCTTTATATATGATGTATTTTCCACAGATGTTTCATGATTTCCAGTTTTCATCGTGTCTTTTTTTTCCTTGTAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGTATTTTTGTCTCGTGTAACTTTTAAGAATAATTTATTTTATGAAGTGATAAACTAAATTTCGTATACCTCAATTGTAGCATGGCTCTGTAAATAAAATTGTATGTGCATAGCTTAAAGTGTGCTACCTCTGGCGTAACTGCGTGGAGTTAAAAACTGTTAAGAACTGGTCAGTATTTTTTTAGCCATTTGCCACATTTGCTTTAAAAATTAGTTCCATTACATTGTTAAGCGTGGTTGAAGTTACGTTTGTTACGTGACTGATTTTTTTTTCCTTTTTGACCTCCCAGTATTTAATTTTTAAAAATGGTTTCTAAAAGTCAAAAAAGTTATTCGTGCTTGTTTTAAAGATTTTTGTCATTAGAGAAATTTTAAAGTAAAACCTGAAAATTCCAGGCTTTTTGCTCCATGTTTCCTTTTAGATTTTTTGTGTGCGTACCCACATATATTTACATTTGAATTTAAATCTATGTTATTGTCCTGTTTGTTGTACTAACAAGATGAAACTGTAGTTGTTCTGTGACTTGCATCCTTGTCAATAAATAAAGTCTACAGAATTCTTTTTAATGGCTGCATAGTATTCCACAGCATGAGTATACCATTTTAAAAATTATTTATGCCTTTACTGATAGGTTTTTAAAAATTGCCTCCTGTTTTTGAGTATTACAGATAGTGCCGCTTTGTACATGCATCCCGTGTGACTATTTCTGTAAGAAAGATTTTATAGAATTATAGGCTGGCCTCGGTGGCTCACCCCTGTAATCCCATCACTTTGGGAGGCCAAGGCGGACCGATCACCTGAGATGAGGAGTTCAAGACTAGCCTGGCCAACATGGTGAAAACCTGTCTCTACTAAAAATACAAAAATTAGTCGGGCATGGTGGCGCGCGCCTATAATCCCCTGCTGAGGAGGCTGGGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCGGTGAGCCAAGATTGCGCCATTTCACTCCAGCCTGGGCGATAAGAGCGAAACTCCGTCTAAAAAAAAAAAAAAGAAAAGAAAAAGATTTTAGAGAATTAGAACTCCTGAGTTCTCAATTTTACTATTTGATTGCTACTGGTAACTTGCTCACCAAAAGGCTCTAACAGTTTCACTCCTGCCAATACTGAATATCACCAATCTTTAATTATTATTATTATTATTTTTTTTGAGGCGGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAATCTCCGTTCCCCGGGTTCACGCCATTCCCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGATCTTGATCCCCTGACCTGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACTGCGCCTGGCCTCTTTTATTATTATTACTATTTTTTTGATAAAAGGTACTGTACCATTGTTTAAATTCATTTTTCTCTAGTTTCTTGGTGAGGCTGGGCACCTTTCCTTTTTGTTTTTGTTTTTGTTTTTTTTGAGACAGAGTTTCACTCCTGTTGCCCAGGCTGGAGTGCAATGGCGAGATCTTGTCTCATTGCAACCTCTGCCTCACGGGTTCAAGCGATTCTCTTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGCATGCGCCACCACGCTCAGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTTTCCATGTTGGTCAGGCTGGTCTTGAACTCCCAACTTCAGGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAATCACTGCACCAGGCCTCCATTTTGTTAAGTCATTTATTTCTTCTGGGACTTGCCTAGTCTTATCTGTCCATTTTCCTTTTAGTTTTTTAAAATTTTTCTTAGTAATTGGAGTAGCTCTATGTGTTTCAAGTATATTTAACTTTTGTTGTTTACTAATGTAGCATTTAATTTTATGTTGTCTTTTCCCCATTGAGAACAATTCTGTGAAGTAAAATTTGTTGGCTTTTGAATTTCATATCATGCTTTGGAAGAACTCTCCTGTCCCAAGATCTTGCAAATATATTCCTATATTTTCTTCTAGATTTAAATTTTTTAAATATTTAGATCTTCACCTGTAATTTACCTTCTTGTTCTTCAATGTAAGATTACAAATGCTATTATCTTTTATAGCTGTTTTCTCATTAATACATGTCTTTTAAGTCACTAATATACTGATGGCTTTCCATTACAGATTTTTTTTTTTTTTTTTTTTTGAGACTGAGTCTTGGTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGCTTCCTGGGTTCAAGCAATTCTGCCGCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCTCCACACCCGGATAATTTTTGTACTTTTAGTAGAGATAGGGTTTCACCATGTTGTCCAGGCTGGTCTTGAACTTCTGACCTCCTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTAAAGGCATGAGCCACTGCGCCTGGCCCACACCTGGGTAATTTTTGTATATTTAATAGAGACGGAGTTTCACTGTGTTGGCCAGGCTGGTCTCACACTCCTGACCTCAGGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGACCTGAGCCACTGCACCTGGCTTCCATTACAGATTTTTACTTTGAATTATTTTATCTAATTTGAAGCTAATATAGCATATAATAAAAATTCAGGAGAAAAAAGGTTATTTTTAAATCTTTTTTGAGAGAGTCCATTCTTTAGCCTGAAAGTAAAGTGCATATGTAAGCACAGTTAAAAAAAAAAAAAGTGATCAGAAAAATTAATAATTCAATTCTATATGTATTTTAAATTTTTCAATTGTTAAATAATATTTGTTTTATTGATTAGCTGGAAATAGGCAATTTTTAAAAATCTGTTTTTAAGGCATCCCCAATGGGGGTGCTGTCAGATTTTAAAGTTAGACAGAGGACCGGGGCATATTAAAGAGAGGTGCAGAGGTACCAGTTTGTGTGGTAGTGGCAAGCTGTAAAGATACTTGAGTTTTGCAGATTTTGATAAACCAAAAGGAAGGGAGAAAGTGCATAGTATATTACATTCCCCTCCCCCATGACAATTATTTTTCTCAAGACCATTTGTAAAACCTCTAGATAAGGGGCAGGCAAATGTTAGCCTGTCAGCCAACTTTGGCCTGTTACCTGTTTTTGTTTTAGTTTTTAAATTTTTTTTGTAGAGGTGGAGTCTCTCAGTGTGGCCCAGGCTGGTCTTGAACACCTAGCCTCAAGCAAACCTCTAGCACTGTCTCCCAAAGTGCTGGGGTTATAGGCAAGAGCCACCTCTCCCAGCCAGCTGCCTTTCTTTCTGTAAGGAAAATTTTACTGGAATGCAACCATGCCCGTTGGTTTACATAGTAGCCATGCTTTTTACTTGGATAGAACCATTTGTATGAAAAGCTTAAAATACTTACAGTCTGGCTCTTTACAGAAAAAAATTGACCCCTAATCTAGTTGGCAGGCTCCTTGCATACAGGTCATATGTCTTATTTGTAATTTCTTTTGCAGTACCTACCACTGTCCAGTGCATAGTAGAAGCTCAATAAATGTTTGTCAAGTAGATATTTGAAATGTAGACTAACTAAGAGGCAGCATGATATAGTAGGAAGAAAATGCTGAGTTGTAGTTGAGGGACCTGGGTTGTTATCTCTGATCTGTTCTTAATTACCCTTGTCAGCTTGGGTTAGTTAGTTAGGTTCTCTAGCCTTCAGGAACCTAATCTTTAGAAAGAGAAGATTGATAACAGGACCCACTCTAAAGATTTATTCATTTCTCTTTGATTCTCTAAGTTAGCTTGCAATAAGCTCGTTGGATCAGTACGGTAAGCTCATTGGATCTCAGTAATTTATGGTTGTTTGTAAGGCAGTAAGCAGGTAATATAAATAGCTGAAGGAAAAAGTAATCTTTGCTCTTTTGGATTGGATACTGTCTGTGATCACAACTGATACTTGATGATTCCATGATACTTGCATAATGATTAGATCCTCCCCAGCATTTTTTCCAAATCCCCTTTATTGAACTTGATGGATATGTTTGCTGCAGGGCCTATAGTTCTGGGATAATTTTGGAAGTATAATAGCAGTTCTTTTCTCTTTATAGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTAAGCTGAATCAAGAGATAAGTAGTATCTCACTAGTTACATGTAGCCATACTTAAAGTTTTCAAGACCATGTGGAGAAATTGGCCATATAGAAGGATTTTTCATTAAGCAGCAACATTTAATTTTGTGGTCGTTTGGACTATATTTTAAAGCTGAAAATTCTAATTATACTCGAGTTTCATTTCTCAGCTAGGAACTCAGATAAATGGAAGCCCCGTAAGGGTGCTTGACCATTTTATGCTGTCAACCCTTTGGTAGACTCCTTCCCAGAATCATGTTTTTAAATGTATGAAATAAAATGTATAGAATTACAAAGGAAACATACTAAAATACGGTTACCAAAATAGTAAACTAGTTTGTGATATGTGTGCTTTTGTTATTAACATAATAAATACTAAGATTTAGAAGAAGATATAATAAATATAATGTTTTTTTGTTTTTTGAGACGAAGTCTCGCTCTGTCACCCAAGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCTAGATTCAAGCCCTTCTTCTGCCTTACCCTTCCAAGTAGCTGGGATTATAGGCACCTGCCACCACGCCTGGCTAATTTTTTGTCTTTTTAGTAGAGATGGGGTTTCTCCATGTTGGCCAGGCTGGTCTTGAACTCCTAGTCTCAGGTGATCCACTTGCCTTGGCCTCCCAAAATGCTGGGATTATAGGCATGAGCCACCATGCCTGGCCAATAAATATTATCTTGATATAGTGAGGAATATAAGTCATATTTTGAAATGTTTGCCATAAGTACAGTATGATAGGAAAACACCTCTGATTTTTGTTGGTGATGAAATCACAGGTATTAATACTGTTGTGATTTGTTGCCTACATTTATAATCGAAGGAAAAGCTAAATTCTAGTTAGAAGTTTGTGAAAATAAGAATAGAATTTTTTTTTTCCCATCCAAATTAATGGACCCCCTGAATTCTATCCAAGGACTTCTTGGGCATCCCTGGATCCCAGGTTAAGAACTTCTGCACTAGAGATACATGAGTACAGTATACTGATCTTTCTGGGATAGAGGTGAGCTGATTCATGACCATATATTCTATCTAATGGTTCCAGCATTTTAATGCATTCCCCACCTTTAAATTTGTGCACAGAAGCATGATTTTCAGTGACAGATTGAGCAACCTTAGGCAGAATTTCAGTGTGATTGAAATATGCCTGTTCTCTGTCTCTCCCACTTAGTTTATGGGACTCAGATTACTTAAAACATTTAAGTTTCTTTCTTACAACGGTATAGTGGGGCAGGAAGAGCTTCCATTTTTCTTTTTCCTCTCCAGCTATACTTTTAGAAACTTCCTTAAAGGATGTTTGGTAGAATAAATCTAAGTTCTCTTCCTTTTTCCTTTCCCACTGCTGGACAGCAATCTGTCCAATCCACAGTCACATAAGAATATTCCTTTAAGGCCGATGCCTGCTTAGCCAGTTAAATCCAAAGACAGTGTTTGTAGGAAAGGGCCAGGTTAAATGGTATTTTTAAGGCTAATTTGGGATTGACCTTATTATCATTGGATAATCAGTTAAGGAAACAAAAAAGTATGGATTTAGCAGTAGATAGAAATGAGAAAATTGGCCAAGGCCATCATAAAGACTTAGAATGCTTATGCTAAACTATGTAACAGTAGTGTATGTATTGTCTGATATAGTTCTCAGTTATAGGATCTTTGTTCTGGGGCACACAGGAAGGTAGTGAAAGCTAGTATGGGTAGTAAAAAGAGCGTTGGATTAAGAGTCAGAAGAGCTGGGGCCAGTTTCTTCTTCTTTTTTTTTTTTTTTTTTTTTTTTATGTGACAGTTTCTCACTCTCTTGCCCAGGCTGGAGTGCAGTGGCATGATCACTGCTCGCTGCAGCCTGGACCTCGTGGGCTCAGGTGATCCTCCCACCTCAGTGTCTGCAGTAGCTAGGACTACAGGCTTGTACCACTATGCCTGGCTAATTTTTGTATTTTTTTGTAGAGATGGAGTTTCACTATGTTGCCCAGGCTGGTCTGGAACTCCTGGGCTCAAGGGATCTGCTTACCTCGGCCTCCTAAAGTGCTAGATTTACAGGTGTGAGCCACTGTGCCCAACGCAATTTCTTCATTTCTAATACAGTGATAATAATCTTATGAAATATCAGAATGAGATAATACTTATAAAAGTACATTGTAAACTGTAAAATGCCATATGTATTTAGGTAGTTGTTAATAGGTTTATATCTGGATATCTTAAAAATGTATTGCCAACTTCTTGTCTTAATGCAGCACAGGGAATATAATTTAACTTTTATTAATGGTTCAAAGTCATTATTTTGATTATTTATCATAATATGGAGTAAATTGATACCTTAGAGGGTTTATTTCATTCTCAGAATTCTCTCAAACTGTTTTGTAGCTGTCATTGATTGATTGTTTTTCTGTCTTCCTCCTCTGGTGACCTCAGAGGCTATTGAGGTTTATAGTATTTATGACTATTTACTAAGTGGCTCCAGACCACTGCCATATTTTAGTTGATTTTTGTTTCTGCAACTTTTTTGGCTATCAGTTTTTTATTTTGCTGCCTTTTCCCTTCCTAATATGTTAGTATCTAAGTATCTGGGCAGAGTTAAAGTCTACAAGGAAAAAAACCTCACATTTTAAGGTTTGCTTAAGTAAATAGAGAAGCAGTTATTTCTGCTTCTGTCAAATTAAATGGAAAAGGCTTAAAAGTAGCTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGAAGTCTCACTCTGTTGCTTAAGCCGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAGCCTCCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCTAATAGCTGGGATTACAGGTGTCTGCCACCATGCCTGGCTAACTTTTGTATTTTTAGTAGAGATGGGACCAGGATGGTCTTTATCTCCTGACCTCGTGATCCATCCGCTTCGGCCTCCCGAAGTACTGGGATTACAGGTGTGAGCCACTGCGCCCAGCCAAAAGTAGCTTCTAAGTACAAAATGGTTGTTCTACATAGTTGTGGATATGGTTCCTGGTTGTTTACCCCTATTCAGATAAATAGGATATTATTAAATGTATTTACAACTAACATTTAGTTTTCTTTAATGCTCAGAAATCATATTTGTATTTCAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGTAATTCTTCAGTTTAGTCCATTGTAAAAAGCCATCTGGGCTAACATTTCAGTTCACCTCTACCCTCATTCACTTTTGTCAGAGAAAAACTGTTGAAACATATTAAAGACATGCTGAAACTTAATTTTTTAGCTCTGCGGCATATTATTTGAGAACCTGAGCTCTGGCATCTTATAAACCAGTGTTTGAAACCTAGCCCAATCATTTACTAGTTTTGTGACTAGATAAATTAACCTTTTTAAACCTGCTTCCCCATTTATAAAATAGGGATAATTAAATACTTCATGTGGAGGTTAAAGCTCTTGAAGAGAGACGTTGTATAAAAAAGCATAGTTTTGGGCACATACAAAGCATTCAAGTATTAGCTGTAGCTATTATAACTTTTTATTCCAGAAACAGTATACCACCACGTGGTAAAGGCTTACATTTGAGCCTTAGTTATTTTGGAGATCATTTTCATTGTCACCTATCATTATGGCACTTAACCAGCAGAATTTAACCCAGGTAATATTTCTAGAAATAGGCCTGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGAGAGGCCAAGGCGGGTGGATCACCTGAGGTTGGGAGTTGGAGACCAGCCTGACCAACATGGAGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTGGGTGTGGTGGTGCATGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGTAGAATCACTTGAACCAGGCAGGTGGAGGTTGTGGTTGAGGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACGAGCAAAACTGCATCTGAAAAAAAAATTTTTTTAATATATATTTTTCTAAAATTATTCTTTTTTTTGTTTGTTTGTTTTGAGAGGGAGTCTTGCTCTATGGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCCGTCTCCTGGGTTCAAGTGATTCTCCTGCCTCGGCTTCCCGAGTAGCTGGGATTACAGGTGCCTGCTGCCATGCCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACGATGTTGACCAGGCTGGTCTTGAGCTCCTAACCTTCGGTAATCCACCTGCCATGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCAACCACACCCGGCCTACATTTGGAATTCTTTGTCACATTTGGTTTAGCACAGGCAATCCGTGTTGAGCCTTAGCATTCATTACATTAATAAATGGAATGAATACGTTCACCTGAGACAATTAACTAGCTTCTGCTAGTATTTAATGCTCAATAGTATAGCTGAAAAGATGATAATTAAATGGGATTTTATTTTATTAAAAAACATAACTTCCTCAGCTGAGCAAGGGATTTTATAACTTTAAAACAACCTTATTATTGTAAACATAGTATATATTATTATTGAACATTAGGAGATGACAGAAAACTAAGAAAAGTAAAGGAAAAAAAAGGACTGTAGTTTGTTAACAAAAGGTATTTTTACCAGTCATTTGTGTATTATGTGCAACTGTGTGTTTTAACCTAGTTATGAATATAGTACTATATTTAAATTTCATCTAGCTTCTTAATTTGTATTATAATTTGTATATTATATATTATAATATACATATAATATAATTATATATATTACAAATATATGTATAATTATTATTTTTTATTGATGAGTCACTTCTGTTTAATATCCATATATGTTGTCATTTTATACGTGGCCTTGGTATATATGGTTTAATTTTATAAATTTTAAAAATAACTATATTGGTATATTGGTGATTTCTTTACCTATTGAATATTGAATCTTCTATTTTTTTTCTTTTTTTTTTGAGATGAAGTCTTGCTCTGTTGCCCAGGCTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCACACTACTATGAGCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACTTCAAGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGACGTGAGCCACTGTGCCTGGTCTGAATATTGAATCTTCGGATAATGTTTGGAAGTATGATTTCCTTGGACTTGAATTCTAAATGTTGAGAGATAAGAAATAGGAGAAATTACTGACTTGAAAAGGATATGAATTAAAAATATTGTGGGTTTAGGTTGCTGTATCCTTATTCCCAAGGATGAAAAAAGATAGTTGGGATTCATATTTCCTCTTAATATTGAGTGAGAAACAATATTTTGTGACAAACACTCTCTTAAATCCTTAGTTTAAAAACAAAAGGAAAAATCCATTGTGACATCAACGAATACTGGGGTAAATGAATTATCCTCCTGTTAGGATATAAACTTCATGAGGGCATATACATTTCTGTTTCATTCTTTGTTTTCCCCCGTGTCTGGTACATAGTACCAGTGACTGGTACGTGGTAGGTTTTCAGTCTGTATTTATTGAATGAATGAGTACTGCTTTATCTGTTAATAAGTTTCTTTTTTTTCTTCCCTGAGTCGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTTGGCTCACCGCAACCTCTGCCTCCCGGGTTTAAGTGATTATCCCGCCTCAGTCTCCTGAGTAGCTGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTTATATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAGCTCCAGGCCTCGGGTGATCTGCCGGACTCGGCCTTCCGAAGTGCTGGGATTACAGGTGTCTGTGAGCCACTGCGCCCGGCCTCTGTTAATACGTTTTAAGATCAAGAAAGGAAGTTGAAGCTTGATGAAAGTCAAGATTATAATCAAATTCCTATTTAATGGATTTTGCGTAACTCAATAGTTTTTTTGGCAGTTTGTATTTAATGGATTTTGCATAACTCAATGCTTTTTTTTGGCAGTTTGCTACTAAGCACAGAGCTAAAAACATTCCTGTTTGAAAATAAGTATGTTCAACCTCTTCCTGCTTGCATACTCATTTTTTGGGGGTCTTCTGGTAAAGTCCAAACAAAGCACATTTCAGGAATTGGTAGTGTGAAATCTTTCAGCTAGAGAGACTTTAGTAATTATTAAAAGTAGCTGTACATAATCATTGTGCTACTAATTATTGTGCTTTTAAGTGCCTACAAGCTTGCCAATGATAAATTTGGTTTTGAATGTGTGCAGTAGTTCATACTAAGTATGTATGTAGAAGTCTGGTTAGATCCAGCTTAATACAAATTTTTATTCTAAAATGTACATCTCTTGTTATTTTTTTTTTTTCTGTCTACAAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGGTAAGTTAATTTTGAGCATCATGGATAAATACCATAAAAACGTTTTAAAGACATTTTTGTTTATGTGCATATGTTTTATAATTGTGATTCTCTTTAAAAGTTGCTTTAATTAAATATTGTAATAAAAGTATGATAAATTTATTAGAAGTACATATGAACTAAAACCACATACTGAGGTTCTAATGTAAAGTTAAATATCCTGTTAGATCAATTTAGACTTGGGATATCAGAGTTAGGATTTATTTTGAAAGGTCTGTAATTTCAAAAGCTCCTGTTTAGGAGTGATCTACCTTGAAAATGTATTGAAAGGCTTTGGGAAATAATATTGTTACCTAGGTAGGACCATGTGTAAGGATGAAGGATGAGTCTTTTTCTTTGGTTATAGACAAAATTTTGTTTACCAATTTGTGGAAGTGGAATTTTATGTTCCTACTTCCGTTTCTTAACTGGTTATTTTTGGGTCACATCTCTCTTTAATAAGCTGATAAAAGCATTGGGTTCTTGTTCCAGAAAGATGCACATGTATATATACATGGGTAAGTCAATAAGTGTTTTACAACCTACTTTCCATGAGAAAAGCCCTGATTTATGTGCTTGCTGACTTCCATAGTATAATACTCTCATTTGAAGGCTAAAAACATGGAGTTGGGAAGAGATGTACACAGTTTGCTTTTTTTTTTTTTTTTTTTTTGAGAAGGAATCTTGCTCTGTCACTCAGGCTGGAGTGTAGTGGCATGATTTCGACTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTTCTGCCTCAGCCTCCCGAGTAGATGGGACTACAGGCGTATGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGAGGGGGTTTCAGCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTGTGATCTGCCTGCCTCGGCCTTCCAAAGTCCTGGGATTACAGGTATGAGCCACTGCACCCGGTCTCACAGTTTGCTTTTGAGTGCTGCTTAGAGCTGTCTCTAATACACTACACTGCTCCTAAAGCCCATCCTCGAACTACAGTTAAGAAATGCTCTTAGGCCAGGTGTGATGGCTCATGCCTATAATTCCAGCACTTTAGGAGGCTAAGGCAGGAGGATCACTTGAGCCGAGGAGTTCAAGACCAGCCTGGGCAGCATGGCAAAATCCTAACTCTGCAAAAACTACAAAAATCAGCTTGGTATAGTGGTGCATGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGGAGGATTTTTTGAGGCTGGGAGGTCAGGACTGTAGTGAACTGTGATCATGCCATCCAGTCCAGGTGACAGAGCAAGACCTCATCTCTTAAAAAAGACAAAAACAAAACAAAACAAAAAAACACCTCTCAGGAGCTTGTTTAGTTCCTAGAATGAATTGACCACTCCCTTGTACTTCCTCTATTCCATATTCAGATTTTATTGTAAAATTGCTTTGTTTTACTTGTGGGTTTTTTTGTTTGTTTTTGAGATGGGCTCTCACTCTGTCACCCTGCTTGAAGTGCAGTGGTAATCTTGGCTCACTGCATCCTCCACCTCCAGGGCTCAAATGATCCTCCCCCTCAGCCTCCCAAGTTGCTGGGACTACAGATGTGCTCCACCACGCCTGGCTAATTTTTCTGTATGTTTGGTAGAGACGGTGTTGCTATGTTGCCCAGGCTAGTCTTGACCTGAGCTCAAGAGATATTCTCACCTCGGCCTCCCAAAGTTTAGGGGTTACAGGCATGAGCCACTGCGTCTGGCTGTTGCACTTGTTTATATTTTTGTTACCTGTGTCCTATTCAGGTTTGCATTGTGCATCACACACTATAGTGTTTTATTAATATGGTATTTAATAAATGTGTTGAATTGAATACTTATTCTTCCAAAGTTAGGATTTAAAGCCCAGAAAAGTATCTCCATTTTATCCCAAAATAAAAGTAGTTATTAGGCTGATGATTTGGCATTTTATTGTTTTAAAGCTCTTTTTTTTTTTGAGCTTTAGATTGTATCCTTTTTATTTCCTTTTTTTTTAATTATTATACTTTAAGTTTTAGGGTACATGTGTACAATGTGCAGGTTGGTTACATATGTATACCTGTTGTTTTAAAGCTCTTTAAGAAATTGTGTGATAGCTAAATATACAATTGTAGTATTTGTAGTAGTAGTTTGAGTTTTCTGAAGTATGTAACCCTGATGTATTCATTCCTTCATTTGTTTAAATAAACTTTGGCACATTACTAGAAAAATTGTATTATTGAGATGGAAACTTACAAATTACTTATTTGCAGTCTGAGTTTGGTTTAGATATCAGTAGAATTAACTTCAGAACTCCTATTCCATGTTCTCAACTTTGTCACTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTCGGATCACTGCAACCTCTGCTTCCCGGGTTTAAGTGATTCTCCTTCCTCAGCCTCCCGAGTAGGTGGGATTACAGGTGCCTGCCACCACGTCCGGTTAATTTTTGTATTTTTAGTAGAGAAAGGGTTTCACCATGTTGACCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAAGTGTGAGCCACTGCACCCACCCAGCCTAGGGCTTCCTTTTTATTACATCTTTTTTGTAGCATCTGTTTATACTAATCCAAAATTCCTGGACAATATAACCTATTATGTACAACTTAAGAAAATTAGTGTAATGCCTTACCCATAGTATAAAGAGAAAATTAATCTATGATAATGCATAATTTCAAAATGTTAATGTCCAGGCATGAGTTCACTGTTAAGATGAAAATGTTTCCAAGGGGGGTAGTAAAGGGTATTTGATGATAATTGTCTGTATATCCCAACTCTGAAACTTTGACTTTTGAGCTCAAAGTCTGTATATCCAACTACAAATGAAACCTATGTGCCTGAATAACTCAGTTTGTTATCTTCCCATCCAATCTGTTTATCTTTCTAAAGTTTCTCTTTTAGTGAATGGTACCACTCATTTATTCACCCAAGTTGGAATCTTGGAATCATCTTAACTCCTTTCTTCCTTGCCTTCTATATCAAATACCAGGTCTTGTTGGTTTTTACCTATTTAATTTCTCTGGAATTTGTTTTCCATGCCTTAGTTTAGGCTTTAATAGTTTTTAGTTTGTATTATTGCAATTGTCTAATACTGGTTTTCCTGCCTCTGCCCTCTTTTTCTTATGTTTTGCTAGAGTGATTTGTCACTCTTCTGCTTAAAATTACCATTTAGGGGTTCATTATTGCTCTCTGGATGTAATATTTTCTGTGAGCTAGAAATCAGTTTCATTTCTTGGACAAAAATCCTTTTTAATGGTGAGTGGCTGCAACATCGCATTAAGGAAGATTCTGAAGTATCTGCGGGGAAGAATGCAGTGATAAGGGAATGACAGCATGAGTCCTGCTTTGGCTAGACCACAGGATCCTTTACAGTCTGAACCTGCCTACATTCCAGTAATAATGAACTGCTTGTGGTGTCCTGCAACAGGAACTGTTGTTAGTTTGCTTTTGGATACTTTTTCACATGGCGTTTTCTTGGTCTGGAATGGCCTTTCCTAGCCCTATTTTCATATTGTCCTACAAAATATTTCCTGATTCTTTGTTTCTCAGACACTCCCTGTCCCTACCAAAATAATGACTCTCCTGTCTCTCTGCTAATTTATCTAACAGTCTTTTAATGTCTTGATTATACTTTACTCTTCTACATTAAAGTTGAATTATTTTATTTACATCTGCAACATTTAGTATGAGGATGCCACCTGGAAAATACATGTTTAATGTTTATTGAAAGGTTAAATTGCATAAGGGTTTGTGTTAGACTGATAGCATATCTACTGAGTAGCGCCCCGCCGCCCCCCGCCCACCACCAAGTTTCTGATCCTTTTTCTTTTCTCTCAGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGTAATCTAAGTAAATTTCTCATTCTAATGTAATATTATTTGCAAATTGGAAAGGTTATTTACAACAAGTTAGCTTACTGGTTATGTTAAGTTTGTTGTATTTTATTTTTTTCCTAAATGCTTAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGGTATATATGAATATTTATTTGACGCATTCACACAGCTTTTTGATATTCTTTCTCTAATGAAATTAGTGCTTTTAGACTTAATTAAATTGTTCCCTTTTTTTGGTTGAGATGAATTAACCTCTGAGTTTTTTTCATTCGTGATTTTATTTGATTTACAAATTGCTTATTTAGCAATATTTTTCTGGCTGACTACAGCAGGCACAGTTTACTGTGCCCCACTGGAGTTTATAGTTAGCCAACTCTCTGTTAAGATAGTAGGAGGTGGCTGGGGTGTGGTGGCTCACGCCTGGCTCACGCCTGTAATCCCGGCACTTTGGGAGGCCGAGGCTGGCGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACGTGGTGAAACCCCATCTCTACTAAAAAAAATACAAAAAGTAGCTGGGCCTGGTGGCGCACACTTGTAATCCAGCTACTCAGGAGGTTGAGGAAGGAGAATCACTTCAACCCGGGAGGTAGAAGTTACAGTGAGCCGAAATTGCGCCACTGCACTCCAGCCTGGGTAACCGTGTGAGACTTCGTCTAAAAAGAAAGATAATAGGAGACAGGCATATAAACTCTATTTTCACCATTATTCTTAGTCACCTTAACAGTTAAATTTTTAAATTGTTATTTTTAATAAATGGTAGTACATACCTATGAGTTTTAAAACAGAAAGTAAATAGCATTTTAGAAATGAAGAGATAAGGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGTCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGGATGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACTGGGGAGGCAGAGCTTACAGTGAGCCGAGATCACGCCACTGCACTCCGCCTGGGCGACACAGTGAGACTGTCTAAAAAAAAGAGAGAGAGAGAAAATAGTTGACAGAGAGAAAATAGTTGAGAACAGTTAGTAGACGTAGTAGACGAGAAGGCTGTTGCCTGAGGAAGTCGCAGTAACTAAGACCGTATGATTCAGATGAAAGAGAATGTCAGATCAGTGAAACAGAATAAATGAACCCAGACCAGAATCTCGTACATGCGGGCAGAAGACAGGAAGGGCAGAGGTGTCTAGGGCAGAGGTGGAACTAGAACAAATGGTAGTTACTTGGGGAAAAGGTGAAGTTAGATCTGTACCTTATGCCAAAATGAATTTCAAATGAGTTTAAAAGTTAAATGAAAAATAGAATACAACATATTTGAAAGATAGTCACTTTAAATTTGACTGTTAATATCTGTATTACATAAAAAGTCTTCCCAAATCAATAAGGAAAACATTAAAACTTCAAATAGCAAAAAGGGCAGACAGTTCACAAAAATTTCTCACAGTAAATACGAATGACTAATAAATATGGGGAGAGGGTGAATTTTGGTGATTTTTAGCTTTACAGATAGTAAAAAATGCCAAAAGGGTGTCCTTTTGATCTATCAAATTAGTAAAAATAAAATTTTTACTCATCCTTACTCATCAGTGCTAATAACTTGTGTATTAGCACTGATAAACTGTTGGTCTGTAAATTGGTAAAAGTGGGTAAAAATTGATTAAATTTTTCGGATTATAAAAAAGCTTAGATGGCCTGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGAAGGCCGAAGCGGGTGGATCTCTTGAGGTTAAGAGTTCGAGACCAACCTGGCCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGTGTGGTGGCAGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGATGTGGAGGTTGCAGTGAACCAAGGTCGCACCACTGCACTCCAGCCTGGGGTACAGAGTGAGACTCCCTCTTAAAAAAAAAAAAAAAAGAAAAGAAAAAAAAGTCTTAGAGTTCTTAACATTATCCTAGTAACTCCATTTCTAGTAATCTATCCTAAGGATGTAATAAAAAATTCAAAGATTTATATGTAGAGATACTAATTACAGCATTATTTATAATTGCAGCCCGGCCAAGATCACCTTTTTAAAAATAGGGAACACAAACATGATTAAGAACTCACGTGCAGAACTTGTGATCTCGATAAAACGTAAAAATCCCGGCCAGGTCCAGTGGCTCACGCCTGTAATCCCAGCACCTTGGGAGGCCGAGGAGGGAGGATCACGAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAAATTAGCCGGGCACAGTGGTGGGCACCTGTAGTCCCAGCTATTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGTGCCGAGATTGTGCCATTATACTCCAGCCTGGGGGACAAGAGTGAGACTTTGTCTCAAGAAAATGATAAAAAAAGTCCTTTCAGAAATCTGTGATACTATCTCATTTTAATTTTTGTCATTCTCATGGGTGAAAAATGATATCATTTCACTTTGCATTTCTTTGATCCCTAGGAGGTAAGAGTTTTTTTTTCTATTACTCAAGTACATGACTCAAGATTTTTCATATGTTTATTAGTCATTTGTATTTCTTCTGTGACTTGCTTTTTCCTGTTTCCTTAAAAGAAAATACAGTCTATCTTGATTTGGTAGGACTTTGTATAATATGTATACTATGGGTAATTTTTACTATATATGTTGCAGATATTATCTTCGAATTTGACCTTTGCCTTTTAACTTTTGTTTGGTATTTTATTTTGTCATGTAAACCTTGACATGGTCTAATCTTGATAGTCTTTTTATTGAGGACTTTGCAGTATTATGAAATACTTCTCCACCCCAGCATTATAAGAATATTTTGTTATAGGTACTTGAATGGTTTTGTTCTTTATATTTAGATCTTTAATCCACCTGGAATTCATTTTTATGTCTAGTATAAGGTAGTATTCTCATTTATGTCTAACGGATTTGTCTAACATTCTGACCCATTCAGAGATAATTTATTATTTAAAATGAAATGGAAACTTTTTACTGGTTTTGATTTCTGTTTAAAATATAGGGTACTGAAGAGCCGGGCTTAGTGGCTTAGGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATCACTTAAGGCCAGGAGTTTGAGACCAGTGTGGCCAACATGGTGAAACCCTGTCTCTACCAAAAATACAAAAATTATCCAGGCATGGTGGTGTGCACCTTTAATCCCAGCTACTTGGAAGCTGAAGTCACAAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAATGAGCTGAGAATGTACCACTGCACTCCAGCCTGGGTGGTCGAGTGTGACTCTGTCTCAAAAGAAAAAGTGTAGGGTACTGAAGAAATTGAAACATTAAGAATACCATATGAGTAAATTAAACACTTTGGCTCTTTTCGGAAAAAAACAGATGAGCTCTTATATTTTAAAGTTTGGTTTTGACAGAAAAAAATTCCTAGATTTTTTGGTTAATAAAAACTTTATTAGATAGATTAAATTGTGATGTATGGAGATAAAGTTCTGAAAGAAGAATAGAAAGCTTTTTAAAAATAGTATTCTCAGCCTAGGCAACATGGTGAAACCCTGTCTATGCAAAAAATACAAAATGGTGCATTCCTATGGTACCGTTCCTATGGTACCAGCTACTCGGGAGGCTGAGGTTGAGGTGGGAGGATCACTTGAGCCCATGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCTCTGTACTCCAGCCTGGGTGACAGAGCAAGACCCTTTCTCAGACAATAAATAAATAAACAAATAAATAAATACACACAGATAGTGTTCTGCTGTAACAGTTGGACAGATTCAATAAAACAGTGTTAACTTTTGAACTAATTTTATTGAAACTAAGTTTCTGTACAAATAGGTACTCAAAACAGCTCAATTTTCTAAATCACAGTACAGCAATTTATTTTTTTTCCTTACATATCCAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGTAATGTTCTCATTTTAAGTAAGGCAAGACTCTTACTGTTCAAAGTCTAGTCCTGGCAGTCCTAATAAGGATACGGATAGAATGTACATGTGTCTTACGAGATTGATAGAAAACACAGTGCTAAATTTTACTTTAAAATAAAACTACTATATTGATCTCCACCTTCAACCCAAGGTATTGTGAGAAATGTGGAAAATAGTGGAGTAACACCGGTATTGGTAAAATTAGTAGTAGTATTAGTAATTATCAATGTCACTGTATGTATTAGAGAATATTTGTGGACCACTGCACCAATAGTACAGTCAAATAAATTGGAGTATAGAGTTGTTTGAGAATTTGAGAGTTACACTTTTTAAAAAAGGAACAAAACCAAAAATTTGGTTCAGTTAAATATTTTAGCATTTTAAGGCAAATTTGACTATTTAGAGTAAAAATATATTTTATTACAGCCATCAGCAAAAAAGTCAGCATAGTCTGAACTTAACATTTGCCAAATAGGTCTAGACATCAGGTAAGTTCTATTTACTTATGCTGTAAAATACAGGTTTATACTGGGCTGGGTGCGGTGGCTCATGCCTGTAATCAGTACTTTCGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCATGGCCAACAAGATGAAACCATGTCTTTACTGAAAATACAAAAATTAGCCAGGCGTGGTGGCGCATGCTTGCAGTCCCAGCTACTTGGGGGCCTGAGGCAGGAGAATCGCTCGAACCCAGGAGTTGGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCTAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAATGCAGGTTTATTATTGCATGGATGACGGGAGAGTATCAGTACTTTCTCATTACTAATACAGACTTCCAAAATATTAGTGAGCAGCATTTCTTAAGAGATGTCACTGAAAGAAGTTTGGTAAAAAATTTTTTTGTTAACAAGAATGCTTGACAAATGGAATATTTTGTTTTGTATGTCTTTAATCAAGCTTGTCCAACCCATGGCCTGTGGGCCATATGCCAGGATGGCTTTGAATGTGGCCCAACACAAATTCATAAACTTTCTTAAAATATTATGATTTTTTTTTTTACAATTTTTTTTCTGCTCATCAGCTATTGTTAGTGTATTTTATGTGTGGCCCAAGACAATTCTTCCAATGTCGCCCACGGAAACCAAAGGATTGGATACATTTTTTGGTAATATGGCAGTGTCTCATGGCCATTATTCTGGGTATTAGTAATCATTGTATAGTACTCTAGAAGATGTAGGAAGTGGAACCAATTGTGATAGTAATCCTAGTCTTTTACCTATTCTTGTTACTTCCTGTATTATCTTTTTTTCTCTTCCAAAGCAGTGATTGTATGAACGCATACCTGCCCTCTAGAGTTACTGTACCTAACGGAGCTGTTACTTATGTAGACCGCTAGATGGCATGATGAGCTCCTGCTCAGTCTGAGAGCAGGTTCTTCATTTGTAGATATTTAAGTTTATACCAAATTCCATACAGTTGAGATGGCACTGCAGATACAGTGGTAGTCAAGGTAGATATGGTTCTTGCCTTCATTGGGAGATAGATCATTAATGACAAAAATGAAAACATTTAATAAATCCAGTGGAAAAAATAGGCTCTTGAGCGGAAATATATGTGATAAAATTGAATCCAATTAAAACTTGATGAGTATCCAACCTACAAGTTTGGTTAAAAAGAGAATTATTATACCCTATTTATTTATTTATTGAGATTGAGTCTCTCTGTCTCCCAGGCTGGAGTGCAGTGGTGCAATCTTGGCTCACTGCAACCTCCACCTCCCCGGTTCAGGCGATTCTCATGTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCTCCCATCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAGCTCCTGACCTCAAGTGATCTGCCTGCCTTGGCCTCCCAAAGTGTTGGGATTACAGATGTGAGCCACCTGCCCGGACCCCTATTTAATGTATAGTTTTTGTTAAAGTTATATCAGAATTCTAGCTGAATGATATTTAGAGTCCTTGTTCCTGCTTTGTACCTGGGACACTGCCTTGTTACTGATATGGCTTTGAGGAGTAGAGGAACACCAGGTTTTTTGTTTTGAGTTGAATTAGATAAAACGACACGGACACACGTGGAGTGGTTTTAAGGAGCAGAGCGTTTAATAGGCAAGAAGGGAGAAGGCAGAAGGAAGAAGCTCCCCCTTACACAGACAGAGGGAGGGGGGCTCTAAAGCTGAAAGAGGAGACCTTACATTCTGACAATACTAGCCAGTTTTATGTGACGGCTGGAGGGGGTGGTGTCTTATTTGCATAGGGCTCAGAGGATTGGTTTGACCAGGCATGTCATTTAGCCCTCAAGAAAACTGGCCCTCCCACCCCAGTCCTTTAATACACAAATGCAGGATGCCATGACATTTTACACACGGGGTTATGTGGGGGCGGCCATGCTGTTAGGTACCTGATGGAGCAAGGGCAAGAGGACAACGGTGGGAATCGCCATGTTGGGTGGACCCTCTTGCATTTGCATCTTAAAGGTTGCCAGCCTTTAAGAGCCAGGGCTTTTATGCTAGACAAGAAATTTTTCTGGAGCTACGAAAAACCTTCCAAGGACCACTTTTCCTCTCCATTTGCCTAAAATAATTTCTTAATAACTCGTGTGGAGTAGAGGGGTATTTCTTTTTTTCTTTTTGTTAGTCCTGTCCTGCATTCTCTTAAAAAATCCTATCTATAAAAAATCTCAGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGAAGGCCCAGGCGGGCGGATCACCTGAGGTCAGGAGTTCAGGACCAGCCTCGCCAACATGTTGTGAAAACCCATCTCTACTAAAAATACCAAAAATTAGCTGGGCATAGTGGCGGGCACCTGTAATCTAGCTACTCAGGAGGCTGAGACAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTGCAGCCTGGGCAACGAGAACGAAATTCCATCTCAAACAACAACAACAAAATCTCGTTTTTCAGGTTAAGTCCCTAGTTGTGAAAGCTTTTGGTAGGGCCAGTTTTTTTTTCTTCTTCGTTTTAATTTCCCTCATTTGAGAATGTTGTAGTCATCATTGGGTGTCATCATTCACCAGTTTGTGAAGGGAGTTAAAGGAAAGTGCATTCCTCTCCCATCTTTTCTTTCTTTGGGGTTTAATAAATTGTGGGAAACTAAGACTGTGTTCTAGACTGTACACCATGCAGTTTATATTATGATCTTCTGTCATCTTTGCAGCCTCAGATTCCATTTTTAGCTAAGACTGGGGTTTTAAATAACTTGTTTAAGGTTCCTACAACTAATTGTCACAATTGGAATTCAAACAATTCTAGGTATTTTTGACTACAAAGATCTAAGATCTTTGCAGAGCAAGCCTATCTGATGCTTAAAAAAATATATATTTTTTAAATTTTTGAGACAGTCTCTCACTCCGTTGCCCAGGCGGGAGTGCAGCGCATGATCATGGCTTACTGCAACCTCAACCTCCTGGGTTCAAGCAATCCTTCCTCCTCAGCCTTGAGAGTTAGCTGGGACTACAGGTGTGCACCACCACACCTGGCTAATTTTTTTTACTTTTTTTTTTTCAGAGATGAGATCTTGGCCTGTTGCCCAGGCTGGTCTCAAACCGCTGGGCTTATGTGATTCTCCTGCTTTGGCTCCCAGAGTATTGGGATTACAGGCATGAGCCACCACCTCCAGCCTGATGCTTTTTAAATATATAGTATTTAGGTCTGGTGCAGTGGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGCGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTATAGTCCCAGCCACTGGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGTGGAGCTTGCAGTGAGCCGAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAATATATATATATATATATTTATATTTAAATAATGTATAAATATATAATATATAATTATAAATCTATTATATATTAATGTATATTATATATTACATTGTTATATATATTTATATAATTATATATTTATATAAATATAAATATATATATTTATATAAATATAAAAATATAATTATATAAATATAAAAATATATATTTATGTAAATATAAATGGGCAGGCACCTGTATATATTATATATATTACTATTTATATAAATATAAATATATATTTTAAATATTTATTTTATATATTTTAAAAATATATATAGAGAGAGATAATTTAATAGTTTCTGGGGCATTCTTTTGCGAACATTAGCCAAAACTTTAAAAACCACTCCCAATATTGCATTTTTTCATGGTATTTTTTATAGTATTTTTATAGTATCCTAGGACAGGAGTTGGCAAACTTTCTGTAAAGAGCCACATAGTTAATTATTTGGGCTCTGCCGGGCCATGGTTTCTGTCACAGCTACTCAGCCCCGCTCTTGTAATGCAGGAGCAACTGTAGACAACAAGTCAACAAATAGGCATGGCTGTGTTCAATAAAACTTTATTTATAAAAGTCGATGGGTGATGGGCCACAGTTTGCAGACCCCTACCGTAGAGTATGTTTTCTGAGATTTAATGTTTCTTGTGATTTACCCCCTTATTCTAAAATTAGTGCACTAAAGACTTTAGTTAGTTGAAGTATTTGGTTTGTTGGGTTACTTTGTTAGTGTTAATTGTATCCTAACTTGACTTGTGATTCTAATCTGATTGGTAGTAGAGCCCTTGTTAGGAATTTGAGCTGCAACTTGATGAATGTTGCTTTTACTCTCCTTCCTAACATTACTCTAAAAAAGTCTTTTGATGTCAGAGGCTGTAAAATAATATACTTTGTTTCTGTTTTTAAAACTGATACAGATATGGAAATCATTTAATCTAAGCTCCTTTTCTAGATGAAGTAGCTACAGCCTTTAGAAGTTAAATGATATGGGCTGGGCGAGGTGGCTCACAGGTGTAATCCCAGCATTTTGGGAGGCCGAGGTGGCGGATCACTAGAGGTCAGGATTTCGAGACCAGCCCAGCCAACATGACGAAACCCCGTCTCCACTAAAAACATAAAAATTAGCCGGGTGTGGTAGTGGACACCTGTAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATAGCTTGAACCCCGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCATTTCATCTTGGGTGACAGAGCAAGACTCTTGTCTCAAAAAAAAAAAGGGCCGGGCATGGTGGCTCACACCTGTAATCCTAACACTTTGGGAGGCCAAGGCGGTTGAATTGCTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAGCCCTGCCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTTGGGAGGTGTAGGTTGCAGTGAGCTGAGATCAGGCCACTGCACTCCAGCCTGGGTGATGGAGCAAGATTCCATCTCAAAATAAATAAAATAAGTTAAATGATGTTGTTTAAGGTTAAATTAGCTACTTAGTGGCAAGTGTAGAATAAGCCATATCCCGACTTCTAGACTTTTTCCAATTGTAGCCTTCTGCTTATATATGCTCCTACCCTTAGCCACTGACAGCAAATATTATTGCCCTGAAGGTCTTACTAGGTTCTTATACAATTTATTGAAGTCCTGAAACGAAGAATCAGATGAGCAGCTACAGAATTTTTTTTAATTGTCTAAAGGCTCTTTAAAAGAAAATCTCAAAGTTTATTAAAAAACATAAGTATCTATGACTCGAGACATTTTTCTAAGAAAAAAAACCCATAAGTATTACAAGTGTTGTGTCTTGTTACGTGTATTCTACCAATTTGGACATAGAAAGATGAGTGACAGGTTTTAGCTCAAAGTATATATAATTCAGATGAGAAACATGCCTGCAAAATTATGTTTTGCATAATTTATGTGTGAGACTATATAATTCATTATTATACAAGTAGTAAGGATAATTAAAGGTGGAAGAGCCTTTTCAGTTATGGTATTGACAAAGGCTTAGTCAAAGAAGGATGAATAGGATTTTGAAACTGAAATTATTCTAGTTAGAGGGGGAAAGTGTGGAAGTTGAAATGCCAAGATTAGTTGAGGAAGCAATCTAGATCTGGCGGGATTATCCATATTTAGTAAGGGAGGAGGGGTGTCTAGTTGAAGACAGACGAAGATGTTAATACAGTCACACTGTAGGTACTTTCGATGCCAAGAGGCTTTGGTGTTTTTCCTTTATGCAGTGGGGTTTTGAACAGGGAAAATAATGTAGTAATAACCTTGAAACCTTAATCTAGTTTCAGTATGCAGGATGGATCTGAGGAGGAAATGTGCGTGGCAACCGGCTCCGGGATGGCTGGCTGGGGGGCCTAGTCTTCTGCCCGCCGATCTCCCTCGGGAAGTCCCGGATCAGAGCAGCAGGCCCATCCCCCAACTGTTACACCCTGCTGGCAGCAGCAGAGGCACAGGGATGAGTTAGGAAACAGATACAGAGGTCAAGAGGTGATGTTTATTAAGTTATATATTTTTTTCTTGTTTTAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTAGTATTTTTTTTCCCCTCTAATTATATTGGAAAATTATTAAATATTTTCTATGTTCATTGACTTTGAGATTGAAATAATATTATTCAGATTTCACTTGAAATCTTTACCTCTTGATTTGTTTAAACTAACACATTGGTTTGTGGACTTGAGGATTTCATAGTTCTTTATCATCTGATTTATATTATTATATTACTACTAATTGCCAAGAAGTCAATAGACCTCAATGAACATGCTTATTATAATGGTCTGTTCACTTTTAAAAACATATAATTCAACTACTGTTTTAATATTAACTTACTTTCTATAAAAGTAAAACATGCATACAGTTAAAGTCAAGTAGTACCCTTAGAGATCTGTTTCCCAGAAGTGACTGCCTTTAACATTTCTAGCTATTTCCCTATTATTTAATATCTCCATATTAGTTATTTATGAAGTAAAACCACCTAGCTGAATGTTTTGTTTTATTCATCCTAAACATCCTTTGTATTGACTTTTACCATTGTGGGTAAGGATTTCTCTCTCCTCCATTTTTTCCCCCTTTACACTCACTTACTCTATTTGATATTGTCTAAGGCTTTCTCATATATTGTAGTACATGATATTTGTTTAGGACTTATTACTAGGAAGCCTTCTGATTGAAGGAAATAGGGCGATGAATTGATGCTAATGAATGTGTTTTATTAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGTAAGTATACATCTACTTTTTTAAGAAATAAAAATTTCATTAAGGTCAAGATTAGGAGACTATATCTAGCTTCTTTCTGAAATGAACTGATTTTTATAAAGTTAAAATGTTTTTGTAAAGTCTGAATAATTTAAAGCATTTTTCTTTTATTTGTTGTGATGAGACCTGTAGCTATAATTTTTATTTTTAGGTGCTGGAATTTGAACTTTTTTTTTTTTTTTTTTAAACAGGGTCTTACCCTTCTCCCAAGCTGGAGTGCAGTGGTGCAATCTCAGTGCACTGCAGCCTCCACCTCCCAGGTTCAAGTGATTCTCGTGCCTCAGTCTCCTGAGTAGCTGGAATTACAGGCATGCACCACTATACCCCACTAATTTTTTTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCATGAACTCCTGACCTCAAGTGATCTGCCCACCTTGGTCTCTCAAAGTGCTGGGATTACAAGCATGAGTCACTGCCCAGCTGAATTTGTACATTTTGATGTTATTTTGGAAAATTTCAGTGTATCTCCAGTATACTCATCACCCAGCTTTAACTATTACCAACATTTTGCCAACCTTGTCAAACGTAAACTTTTTTTTTTTTCAATTGAGATAGGGTCCTGCCCTGTCTTCCAGGCTGGAGTGCAGTGATGTGATCATGGCTCACTGCAGCCCCCACCTCCCAGGCTCAAGTGATCCTCCCACCTCAGCCTCCTGAGTAGCTGGAATAACAGGTGCATGCCATCACACCCCAGCTAATTTTTGTATTTTTTGTAGAAATGTCACCATGTTGCCCAGGATGGTCTTGAACTCCTGGGCTCAAGTGATCCACCTGCCTCAGTCTCCCAAAGTGCAAGGATTACAGGTGTGAGCCATCACACCCAGCCAAATGTAAACATTTTTATTACTGATTTGTATTATAGAATGTGGTAGGATTTGCCATTAAAGAAATTAACACTTAAATGTTTACATCTCATGCATACTTCACTGAGTTCCTGAGGTATTATAGGTTTTTTTAAAACTATTGTGCTTTAGTTTTTGTTCTTAATATTGCCTTTATTATATTTGAATAGGAAATAAATTCCATTTTTTCTGAGTTATAGACAGTTACTAATTATTCAAGTGCAAAAAAGGATGAAAATTCAAGAGTTTCCAAAATTTTTACTGTATTAGAAAATAAATAACTAATTGAATCATTTGATGTCAAGTTGAGTAAAATATTTTAGATACTTTTAATTTTTTAAATCTATTTTAAGACTCAAATTATTTTAGATATTCATCTTGGAATTTATTGGACTTTTTGATGCACTTTTACTCCCATATTGCAAGACCTTTTTCTTTGGTTTTATGAGCTGTGAAAAACCCCCTTCTATAACTTGAAAAAAGAAGAATGAATAGTCTATCTTTATTGCTCCTGTCTTAACATCATTTGTGAGGCAATCTCAAAATGGTTACGGAAATACCTCTTACTTAAGAGTTTTCACTTGTTAAATGTCCTCAGGCAAGAACCATGCTTCAGCTAAGGCAAGAAGATAGGTTATGTAAAAAGGCTGGGGATGTGGGAGAGTTTGTTATCCAAATTGCATGGTGGAAAGGTTTGTGGGATAAAACGTTGGGAAAAGGAAGAAGCATTGAGCAGTTACAAAGATGAGAACACAGGAAAGGATAGACAGGTAAAGGAAAGGATATTACGGTTAGTGACCAAGGATGATAGGTTTTAGCAGCAATACTTGCTGTGAAAAATGTTTTAGCATTTCTCTTGTGGATGGAGTTAGGGAATACTCAGTTAAGCCATGGTTTTAGAGTACTTCTAAGGTAGTTCTAGTCACTGGTGGATTAGGAAGTCTTTCTCGAGGAGGCAGGTTTCATCTAGATTGATGGGATGGACTCTTGGAATAGCGCCTAGGGTTGAGCCTTTAAGGGAGTGGATATAGGCTGCATGACAGAGTAAAAGATCCCATAGACTTGCTTCAACTAAAGGAAGCAACTGCATTTGTATCCTGAAACAGATAACTTTATAGGTACATGATTAATATCACATCACAGTTAATATATTTTTAGTTTAGAATTTTTCAGGATGGTAAGGGTGAAAAAAATGGGTGTACTTACTCTACTTTAGGAGAGACTGTTACATATTGACCTTTAAAAATCTGTTTTGTGTATAATTGAGACATATAACGTGATGTTTTGACACACATGTAAATAGTGAAATGATCACTACAGTCAAGCAAATTAATGTAATCCATTATCTTGAATAGTTAACCTTTCTTGTGTGTATGGTTAAAATACCTAAAATCTATTCTTTTAGTAAATTTCCAGTATACCAATATATAACTAACTATAGTCCTCATGCTGTTTACAGTGACTATTTTATATAAAACATGAAACACTGAATATTGAGCCCTATGATATACTTTACCTTAGACATAGCAAAGTTGCTAGCATTCCTGTGACTGAGCAGTTAAAGGGTTACAGAAACTGACTGTGTGTCTTATTTCATTGAAGGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCTTCTGGGTTC

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